Our People - University of Waterloo

MASc thesis: Towards a Chemically Defined Medium for Sf-9 Cell Culture: Micronutrients Reduce Dependence on Yeast Extract 

MASc thesis: An In-Depth Look at Repeated Propagation of Multiple Viruses Simultaneously in Insect Cell Culture

Co-supervised by Brian Ingalls, Department of Applied Mathematics, Faculty of Mathematics

Co-supervised by Brian Ingalls, Department of Applied Mathematics, Faculty of Mathematics

Recipient of an NSERC CGS-D scholarship as well as a Ken O’Driscoll Graduate Scholarship in Polymer Engineering/Science for his work on plastic biodegradation.

Co-supervised by Brian Ingalls, Department of Applied Mathematics, Faculty of Mathematics

Co-supervised by Roderick Slavcev, School of Pharmacy, Faculty of Science and supported in part by the NSERC (Natural Sciences and Engineering Research Council) CREATE grant PrEEmium

Co-supervised by Roderick Slavcev, School of Pharmacy, Faculty of Science and supported in part by the NSERC (Natural Sciences and Engineering Research Council) CREATE grant PrEEmium

Co-supervised by Roderick Slavcev, School of Pharmacy, Faculty of Science and supported in part by the NSERC (Natural Sciences and Engineering Research Council) CREATE grant PrEEmium.

Nicholas is also an entrepreneur and has secured funding from GreenHouse in the cultured meat area: Entomatia

Co-supervised by Roderick Slavcev, School of Pharmacy, Faculty of Science and supported in part by the NSERC (Natural Sciences and Engineering Research Council) CREATE grant PrEEmium

MSc thesis: Design of a DNA-Encoded Human Papilloma Virus-Like Particle Displaying a Vascular Endothelial Growth Factor Antagonistic Peptide for Characterization in Mammalian Cells

MASc student, co-supervised by Roderick Slavcev, School of Pharmacy, Faculty of Science and supported in part by the NSERC (Natural Sciences and Engineering Research Council) CREATE grant PrEEmium

MSc Thesis: The Construction and Characterization of a Synthetic SARS VLP Comprised of Betacoronavirus Consensus Sequence-Encoded Viral Components

PhD thesis: Development of a Serum-Free Chemically Defined Medium for Adherent and Suspension Culture

MASc thesis: A flow cytometry based assay for the quantification of viruses using changes in infected cell granularity

PhD Thesis: Toward Optimization of the Baculovirus Expression Vector System - Development of Genetic Tools to Improve Biologics Production

PhD thesis: Development of Physically Modified Starch Microparticles for Uptake and Release of Drugs

Co-supervised by Frank Gu, University of Toronto

Co-supervised by Roderick Slavcev, School of Pharmacy, Faculty of Science and supported in part by the Natural Sciences and Engineering Research Council (NSERC) CREATE grant PrEEmium and Theraphage.

PhD thesis: Droplet Production of Biological non-Newtonian Fluids and Bioassay Applications in a Microfluidic Network

Co-supervised by Carolyn Ren, Department of Mechanical and Mechatronics Engineering

MASc thesis: Understanding the Sf9 – Baculovirus Expression Vector System: Exploring the Metabolic Basis of the Cell Density Effect through Nuclear Magnetic Resonance Spectroscopy and Flow Cytometry Analysis of Fluorescent Protein Accumulation

MASc thesis: Establishing the Virucidal Properties of a Copper-Nickel-Zinc Alloy using a Genetically Modified Insect Virus

MASc thesis: Generation and Characterization of Dual-Fluorescent Influenza Virus-like Particles (VLPs) in Insect Cells

MASc thesis: Towards the Development of a PhiC31Int-Competent Sf9 Cell Line

Video: 3 Minute Thesis

PhD thesis: Supplementation Strategies for Enhancing Growth and Product Quality in Mammalian Cell Culture Bioprocesses by Omics Analysis & Tuning glycosylation of Monoclonal Antibodies

MASc thesis: Investigation of excipients for the stabilization of HSV-2 vaccine candidate ACAM529

MASc thesis: Partial Characterization of yeast Hydrolysates for Insights on Chemically Defined Media for Sf9 Insect Cells

PhD thesis: Use and control of co-expression in the baculovirus-insect cell system for the production of multiple proteins and complex biologics

MASc thesis: Real time PCR protocol development for rapid low cost quantification of baculovirus and for monitoring progression of infection

PhD thesis: From metabolite concentration to flux analysis - a systematic assessment of error in cell culture metabolomics

MASc thesis: Tracking uptake, assembly and egress of ACAM529 Herpes simplex virus type 2 in complementary Vero cells for enhanced virus recovery

Co-supervised by Guy Guillemette, Department of Chemistry, Faculty of Science.

MSc thesis: Production of a camelid antibody in CHO cells and its potential for the in vitro modification of its N-glycan using N-acetylglucosaminyltransferase III produced in insect cells

MASc thesis: Characterization of alternative promoters to stagger and control multiple gene expression and protein production in the baculovirus-insect cell system

MASc thesis: Investigation of a novel hydrogel anion exchange material for the capture and purification of baculovirus vectors

MASc thesis: Investigation of Sf9 cell metabolism before and after infection using biovolume: A case for the improvement of adeno-associated viral vector production