Contact Us:
Centre for Bioengineering and Biotechnology
University of Waterloo, East Campus 4, Room 2001
200 University Avenue West
Waterloo , Ontario, N2L 3G1 Canada
cbb.uwaterloo.ca
519-888-4567 Ext 32732
Research Interests:
[YouTube Lecture] September 30, 2014 "An engineering prospective on Cancer'
Research Interests:
Health informatics
Clinical problem solving, reasoning, and decision making
Cognitive methodologies for the analysis of human computer interaction, knowledge acquisition, and medical expertise
Cognitive aspects of computerized clinical practice guidelines
Research Interests:
Research Interests:
Biomedical optics
Tissue optics and spectroscopy
Ultrafast optics, coherence tomography, sensing, imaging
Confocal and fluorescence microscopy
Skin cancer detection
Atomic, Molecular and Optical Physics
Research Interests:
Research Interests:
Confocal microscopy and ophthalmoscopy, measurement of refractive error
Retinal image quality
Optical effects of refractive surgery, reflections from the retina
Optical properties of the eye, monochromatic aberrations of the eye
Refractive properties of the crystalline lens and their changes with growth and accommodation
Eye-imaging systems for treatment and diagnosis
Biophysics, bio-photonics, and Vision Science.
[Research2Reality] May 8, 2015 "Early Alzheimer's Diagnosis: Imaging the Living Eye"
[YouTube Lecture] October 1, 2014 "Optics of the Eye as a Window on the Brain"
[YouTube] February 12, 2013 "Melanie Campbell AAAS Profile"
[Waterloo Stories] February 12, 2013 "An early test for Alzhemer's disease"
[Waterloo Stories] January 22, 2013 "Early test for Alzheimer's may rely on the eyes"
Office of Research - Technology Transfer & Commercialization:
Research Interests:
Cancer research
Cell cycle, DNA replication, biomarkers and checkpoints
Genetics, yeast genetics, molecular biology
Protein factors
Kinases
Chromatin
[CBB researcher story] January 2, 2013 "How the Trout are Saving Us: Using Biomarkers to Improve Water Quality"
Research Interests:
Research interests:
[Science Direct] August 10, 2018 "Revealing the atomistic details behind the binding of B7–1 to CD28 and CTLA-4: A comprehensive protein-protein modelling study"
[Nature] August 27, 2019 "Comprehensive in vitro characterization of PD-L1 small molecule inhibitors"
Research interests:
[Waterloo News] February 6, 2019 "Researchers find new treatment for Chlamydia"
[Waterloo News] April 16, 2018 "Developing new way to fight transmission of HIV"
Research interests:
Research Interests:
Methionine chemistry and biochemestry (amino acid methionine and its roles in proteins, cellular pathways and its functions)
Bionanomaterials, bionanotechnology (for novel drug carriers, molecular foundations for nanodevices)
Medicinal chemistry
[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners
Research Interests:
[CBB researcher story] August 6, 2015 "Decreasing antibiotic resistance in bacteria"
[YouTube Lecture] September 30, 2014 "Model-based design in synthetic biology"
Research Interests:
[American Chemical Society] January 23, 2012 "Exploring Inhibitor Release Pathways in Histone Deacetylases Using Random Acceleration Molecular Dynamics Simulations"
[Wiley Online Library] July 27, 2013 "Ligand release mechanisms and channels in histone deacetylases"
[Royal Society of Chemistry] December 19, 2013 "A steered molecular dynamics mediated hit discovery for histone deacetylases"
[Nature Methods] May 8, 2017 "ModelFinder: fast model selection for accurate phylogenetic estimates"
[Royal Society of Chemistry] October 24, 2017 "Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction"
Research Interests:
Low-dose, low-cost x-ray imaging system (e.g. tuberculosis screening)
Circuit technology, Photon counting circuits for biomedical imaging
Large area digital medical imaging
Silicon Thin-film Applied Research
Device physics
Amorphous semiconductors and semiconductor devices
[Engineering News] November 12, 2018 "New X-ray technology to be tested on cancer patients"
[YouTube Lecture] September 30, 2014 "Bending the cost curve: Building a $1000 diagnostic X-ray imager for scalable and sustainable healthcare"
[Office of Research] "Paving the way for a digital X-ray and health-care revolution"
Research Interests:
[Waterloo News] June 23, 2016 "Nanotechnology and math deliver two-in-one punch for cancer therapy resistance"
[Waterloo Stories] February 11, 2015 "Study finds new lethal combination of cancer drugs shrinks tumors"
[Waterloo Stories] January 16, 2018 "Math can predict how cancer cells evolve"
Research Interests:
Research Interests:
microrobots
We develop microrobots for medical applications. The goal is to develop more targeted, active, but less invasive strategies for drug or cell delivery with the help of wireless, autonomously moving microrobots. One strategy is to combine biological elements with artificial components in a biohybrid approach. The biological component (cells, molecules) can serve as power source, loading unit or structural unit.
One example is the "spermbot" - a sperm cell remotely controlled with magnetic fields: https://phys.org/news/2014-01-sperm-bots-desired-video.html
Another example is IRONSperm: a magnetically functionalized nonmotile sperm driven by magnetic fields:https://www.science.org/doi/10.1126/sciadv.aba5855
Inspired by the motion of sperm, we also develop small scale flexible magnetic robots for noninvasive surgery (coming soon). I am also interested in reproductive biology and research that elucidates reasons for infertility. We look into the mechanisms of sperm migration and some interesting phenomena, such as sperm bundling (publication online soon)
[Google Scholar]
Research Interests:
Protein structure, functions, evolution (yeast, mammalian cell lines, plant-bacterial)
Bioinformatics, systematics and protein evolution
Research Interests:
Proteins: energetics, kinetics, mechanisms, structure, dynamics, folding, function, evolution, engineering and design, thermodynamics, kinetics (ALS, Alzheimer's, Parkinson's, prions, cancer)
High resolution nuclear magnetic resonance spectroscopy (fluorescence, CD, NMR, FTIR, DLS)
Optical spectroscopies
Bioinformatics and computational modelling
Biocomputing and protein engineering
[Waterloo News] November 24, 2015 "New insights into protein structure could change the future of biomedicine"
[Chemistry News] August 20, 2014 "Chemist Elizabeth Meiering takes on the ALS ice bucket challenge"
Research Interests:
[MaRS] April 26, 2018 "UbiLab team wins Healthy Behaviour Data Challenge"
Research Interests:
Research Interests:
[Science News] October 22, 2018 "Nekkar lab determines that depression medications can help treat Alzheimer’s disease"
[Pharmacy News] July 29, 2015 "Waterloo pharmacist examines drug therapies for Alzheimer’s disease"
Research interests:
Research Interests
Research Interests:
Biomedical applications of electromagnetics
Electromagnetic compatibility, interference, propagation mechanisms
Material measurements, metamaterials and its engineering applications
Energy harvesting
Surface and subsurface detection using near-field microscopy
Electronic packaging
Photonics
Radiating systems, theoretical and computational electromagnetics
Research Interests
[Linkedin]
Research Interests:
[Applied Mathematics Biomedical Research Group]
[Waterloo Stories] January 16, 2018 "Math can predict how cancer cells evolve"
Research Interests:
Drug discovery, delivery systems and nanomedicine
Gene therapy, microbial genetics
Oncology, Antiviral therapeutics design
Anti-bacterials
Acne cosmeceutical design
Phage-based biotechnology
Viral exclusion systems
Cosmeceuticals
Vaccine design (dementia), bacteriophage-based biotechnology, use of coliphages to design and construct vectors for the development of novel vaccines, pharmaceuticals and gene delivery systems, and the identification and application of novel phage genomic anti-bacterial genes with potential phage therapy applications.
Strategic management in Pharmacy; healthcare reform
Research Interests:
Medicinal chemistry/enzymology (treatment of prostate and breast cancer, diabetes)
Nanomedicine; development of novel antibiotics
Bionanomaterials; synthetic polymers and methodologies
Peptide, charbohydrate, nucleoside and nucleotide chemistry
[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners
[Science News] February 4, 2015 "Chemists develop new method to improve the discovery of antibiotics"
Research Interests:
Biochemistry and molecular biology of programmed cell death
Functional genomics of senescence (biological aging) and apoptosis
Comparative aspects of senescence and stress including the role of hormones and the involvement of free radicals
Applicable therapies for cancers, inflammatory diseases (arthritis and sepsis), and in the agricultural sector (enhance yield, develop tolerance to environmental stress and plant diseases, and increase the shelf-life of perishable produce)
The Royal Society of Canada Fellow
Research Interests:
Canada Research Chair in Scientific Computing [Canada Research Chair Profile]
Research Interests:
Gene therapy and drug delivery systems (prostate and ovarian cancer treatment)
Polymeric nanomaterials, biopolymers
Novel surface active compounds (gemini surfactants)
[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners
[CBB researcher story] July 21, 2015 "Vectors for gene therapy and improving drug solubility"
Research Interests:
Biomaterials and mechanics of biomaterials and tissues
Bone quality and fragility, collagen
Engineering of bone mimetic materials for skeletal reconstruction (3D printing)
Research Interests:
Biomedical image processing and analysis (prostate, breast, lung and dermatological cancer analysis, retinal photoreceptor and blood vessel analysis, musculoskeletal kinematic analysis
Remote sensing data processing and analysis (sea ice, underwater object, oil spill analysis)
Perceptual based video and image processing (noise reduction, compression, enhancement)
Computer vision and pattern recognition
Multimedia management systems
3D graphics and game development
Cognitive radio networks
Canada Research Chair in Medical Imaging Systems [Canada Research Chair Profile]
[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners
[Waterloo News] [CBC News] [Gadgets] May 16, 2018, Co-authors discuss the use of aerobic fitness data from wearable tech to predict illness
[Waterloo News] May 15, 2018 "Researchers combine wearable technology and AI to predict the onset of health problems"
[Global Impact] [570 news] [Youtube] April 11, 2018 "How AI is helping doctors diagnose Cancer"
[The Star] February 9, 2018 "How TheRedPin aims to take a swipe at the real estate industry"
[Waterloo News] June 7, 2017 "Artificial intelligence-driven imaging research makes diagnosing disease easier"
[Waterloo Stories] January 28, 2017 "Artificial intelligence and the Waterloo-Toronto tech supercluster"
[Waterloo Stories] May 20, 2016 "Breakthrough tech helps doctors more accurately diagnose cancer"
[CBB researcher story] January 9, 2013 "Improving Early Diagnosis to Save Lives"
[Waterloo Stories] January 9, 2013 "Making it harder for cancer to hide"
[YouTube Lecture] October 1, 2014 "Integrative systems for biomedical imaging and analysis"
Research Interests:
Data mining and bioinformatics
Machine intelligence, computer vision, intelligence robotics
Pattern recognition and discovery methods of genomic and proteomic data
DNA sequencing, colon cancer and leukemia gene and data analysis
[YouTube Lecture] September 19, 2013 "Pattern discovery and analysis of genomic and proteomic data"
Office of Research - Technology Transfer & Commercialization:
Research Interests:
MEMS/NEMS
Nanodevices and carbon nanotube-based sensors for biomedical applications (early disease detection)
Microassembly and micromirror devices for genetic microarray reading and tissue imaging
Lab-on-a-chip designs
Canada Research Chair in Micro and NanoDevices [Canada Research Chair Profile]
Centre for Bioengineering and Biotechnology
University of Waterloo, East Campus 4, Room 2001
200 University Avenue West
Waterloo , Ontario, N2L 3G1 Canada
cbb.uwaterloo.ca
519-888-4567 Ext 32732
The University of Waterloo acknowledges that much of our work takes place on the traditional territory of the Neutral, Anishinaabeg and Haudenosaunee peoples. Our main campus is situated on the Haldimand Tract, the land granted to the Six Nations that includes six miles on each side of the Grand River. Our active work toward reconciliation takes place across our campuses through research, learning, teaching, and community building, and is centralized within our Office of Indigenous Relations.