Centre for Bioengineering and Biotechnology
University of Waterloo, East Campus 4, Room 2001
200 University Avenue West
Waterloo , Ontario, N2L 3G1 Canada
519-888-4567 Ext 32732
Translational research in healthcare and medicine
[Waterloo Stories] July 10, 2017 "Waterloo software improves care for kidney patients"
[CBB researcher story] July 21, 2015 "Data management in Health Care"
Intelligent drug delivery system design (dermal, transdermal, transmucosal, ocular, and intranasal) for Dermatology, Ophthalmology, Cancer, Immunology (Glaucoma, neural degenerative disorders, HPV, LSIL/CIN I, cervical cancer, Scleroderma)
Non-invasive drug delivery technologies, biomolecular devices
Gene therapy, protein, and vaccine development
Nanomedicine, pharmaceutical development
Nanotoxicology (nanomaterials, bioimaging, biomarkers)
[Waterloo Stories] July 5, 2012 "Revolutionary drug delivery"
Mobile health technologies and social media in medication management
Clinical and post-marketing phases of medication use
Improve medication use and primary care via emerging technologies (mobile apps, social media)
Pharmacy remuneration models and chronic disease management services in the community pharmacy setting
Usability of mobile health applications and wearable activity trackers for older adults living with chronic disease.
[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners
[Waterloo Stories] November 16, 2016 "The opioid crisis: How pharmacists can help save lives"
[Waterloo News] February 6, 2019 "Researchers find new treatment for Chlamydia"
[Waterloo News] April 16, 2018 "Developing new way to fight transmission of HIV"
CIGI Chair in Global Health Economics [CIGI Profile]
[AHS News] March 15,2018 "Part of international team examining medical testing in resource-limited countries"
University Research Chair
Office of Research - Technology Transfer & Commercialization:
Integrative kidney physiology
March 29, 2018 "Canada 150 Research Chair joins Department of Applied Mathematics"
Biophysics of lipids and lipid-protein interactions
The role of structural changes and physical properties of lipid template in controlling biological processes and diseases
Biomedical nanotechnology (lipid films, molecular mechanism of Alzheimer's disease)
Drug development and delivery systems, antimicrobial peptides in lung disorders
Fluorescence and atomic force microscopy
Kelvin probe force microscopy and single molecule force spectroscopy
[Global Impact] May 2018, studying Alzheimer's at a molecular level to find a cure
[YouTube Lecture] October 1, 2014 "Scanning probe microscopy in biomedical research"
We develop microrobots for medical applications. The goal is to develop more targeted, active, but less invasive strategies for drug or cell delivery with the help of wireless, autonomously moving microrobots. One strategy is to combine biological elements with artificial components in a biohybrid approach. The biological component (cells, molecules) can serve as power source, loading unit or structural unit.
One example is the "spermbot" - a sperm cell remotely controlled with magnetic fields: https://phys.org/news/2014-01-sperm-bots-desired-video.html
Another example is IRONSperm: a magnetically functionalized nonmotile sperm driven by magnetic fields:https://www.science.org/doi/10.1126/sciadv.aba5855
Inspired by the motion of sperm, we also develop small scale flexible magnetic robots for noninvasive surgery (coming soon). I am also interested in reproductive biology and research that elucidates reasons for infertility. We look into the mechanisms of sperm migration and some interesting phenomena, such as sperm bundling (publication online soon)
Proteins: energetics, kinetics, mechanisms, structure, dynamics, folding, function, evolution, engineering and design, thermodynamics, kinetics (ALS, Alzheimer's, Parkinson's, prions, cancer)
High resolution nuclear magnetic resonance spectroscopy (fluorescence, CD, NMR, FTIR, DLS)
Bioinformatics and computational modelling
Biocomputing and protein engineering
[Waterloo News] November 24, 2015 "New insights into protein structure could change the future of biomedicine"
[Chemistry News] August 20, 2014 "Chemist Elizabeth Meiering takes on the ALS ice bucket challenge"
[MaRS] April 26, 2018 "UbiLab team wins Healthy Behaviour Data Challenge"
[National Centre for Biotechnology Information] August 31, 2019 "Key factors for the assessment of mobility in advanced dementia: A consensus approach"
[Ontario Neurodegenerative Disease Research Initiative] September 26, 2019 "Wearable technologies to improve health outcomes in people with neurodegenerative diseases?"
Protein and DNA separation analysis towards disease diagnosis and drug discovery
Biosensing and Devices (bacterial, proteins, fluorescence)
Living cell analysis and water toxicity testing
Lab-on-a-Chip technology (point-of-care biomedical diagnosis , chemical detection, protein separation and identification, environmental testing)
Micro-scale fluid mechanics, droplet microfluidics and nanofluidics
Canada Research Chair in Lab-on-a-Chip Technology [Canada Research Chair Profile]
[Waterloo Stories] June 14, 2012 "Creating the tiny future of science"
[CBB Events] November 15, 2019 "Professor Shaker organizes a Health Canada Regulatory insights Workshop"
[CNN] November 11, 2019 "Scientists develop sensor to save children and pets from hot car deaths"
[Waterloo News] October 29, 2019 "Advancing healthcare through innovative technology"
[Inside Digital Health] June 3, 2019 "Study: Radar Monitors Sleep with Accuracy Comparable to Current Standards"
[Waterloo News] June 28, 2018 "AI and radar technologies could help diabetics manage their disease"
[Engineering News] June 28, 2018 "Researchers developing a prick-free glucose monitor"
[RD Magazine] June 28, 2018 "AI and Radar Technologies Could Help Diabetics Manage Their Disease"
[Engineering News] July 5, 2016 "Waterloo wins big with tiny power device"
Rehabilitation engineering and assistive technologies (gerontology, Osteoporosis, Alzheimer’s disease, fall risk in stroke survivors, and rehabilitation following traumatic brain injury)
Biomedical signal analysis
[Waterloo Stories] July 8, 2014 "GPS technology may help detect Alzheimer’s disease earlier"
Stem cells, nanofabrication and advancement of biomaterials in healthcare technologies to repair, replace or regenerate damaged tissue and organ structures
Fabrication and application of nano-structure for biomedical applications in neural, vascular, and cornea tissue engineering
Biomaterial approach to study ex-vivo pluripotent stem cell expansion
Modulation of cell behavior with nanotopography
Topography-regulation of stem cells lineage commitment and differentiation
Differentiation of adult and pluripotent stem cells with nanotopography
The University of Waterloo acknowledges that much of our work takes place on the traditional territory of the Neutral, Anishinaabeg and Haudenosaunee peoples. Our main campus is situated on the Haldimand Tract, the land granted to the Six Nations that includes six miles on each side of the Grand River. Our active work toward reconciliation takes place across our campuses through research, learning, teaching, and community building, and is centralized within our Office of Indigenous Relations.