Contact Us:
Centre for Bioengineering and Biotechnology
University of Waterloo, East Campus 4, Room 2001
200 University Avenue West
Waterloo , Ontario, N2L 3G1 Canada
cbb.uwaterloo.ca
519-888-4567 Ext 32732
Research Interests:
Assistive Robotics and Rehabilitation Engineering
Research Interests:
[Office of Research News] March 12, 2018 "Received Early Researcher Award"
Research Interests:
[American Chemical Society] January 23, 2012 "Exploring Inhibitor Release Pathways in Histone Deacetylases Using Random Acceleration Molecular Dynamics Simulations"
[Wiley Online Library] July 27, 2013 "Ligand release mechanisms and channels in histone deacetylases"
[Royal Society of Chemistry] December 19, 2013 "A steered molecular dynamics mediated hit discovery for histone deacetylases"
[Nature Methods] May 8, 2017 "ModelFinder: fast model selection for accurate phylogenetic estimates"
[Royal Society of Chemistry] October 24, 2017 "Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction"
Research Interests:
[Waterloo News] August 19, 2015 "Wearable technologies will improve stroke rehabilitation"
[Waterloo Stories] February 4, 2014 "Finding your way after a stroke"
Research Interests:
Biomechanics engineering (injury rehabilitation, assistive devices for elderly, athletes, disabled)
Mechatronic and robotic systems
Multibody system dynamics
Computational methods for analysis and design
Advanced vehicle systems
Canada Research Chair in Biomechatronic System Dynamics [Canada Research Chair Profile]
NSERC/Toyota/Maplesoft Industrial Research Chair in Mathematics-Based Modelling and Design [NSERC Profile]
[Waterloo Stories] February 20, 2019 "Engineering innovation for wheelchair curlers"
[Waterloo Stories] August 5, 2016 "Rio Olympics 2016: Engineering speed for the Canadian track cycling team"
[Waterloo Stories] June 17, 2015 "Waterloo’s $10M dream facility for smarter, greener cars"
Office of Research - Technology Transfer & Commercialization:
Research interests:
Research interests:
Research Interests:
Research Interests:
Calcium channel analysis for target drug delivery for treatment of pain, arrhythmias, angina, and potential benefits in treatment of epilepsy and cancer.
Structure, function and pharmacology of calcium channels and sodium channels
Structure and function and analysis of NALCN cation channel and anti-calcium channel toxins
The Spafford Neurobiology Research Laboratory studies voltage-gated calcium channels, molecular physiology, biophysics, cell biology, protein biochemistry, fluorescence microscopy and tissue cultures.
[Science News] April 25, 2014 "Waterloo discovers a key regulator in the pacemakers of our brain and heart"
Research Interests:
Rehabilitation engineering and assistive technologies (gerontology, Osteoporosis, Alzheimer’s disease, fall risk in stroke survivors, and rehabilitation following traumatic brain injury)
Neuromotor control
Biomedical signal analysis
[Waterloo Stories] July 8, 2014 "GPS technology may help detect Alzheimer’s disease earlier"
Research Interests:
Stem cells, nanofabrication and advancement of biomaterials in healthcare technologies to repair, replace or regenerate damaged tissue and organ structures
Fabrication and application of nano-structure for biomedical applications in neural, vascular, and cornea tissue engineering
Biomaterial approach to study ex-vivo pluripotent stem cell expansion
Modulation of cell behavior with nanotopography
Topography-regulation of stem cells lineage commitment and differentiation
Differentiation of adult and pluripotent stem cells with nanotopography
Research Interests:
Ultrasound imaging innovations: Complex flow imaging, High-performance beamforming platforms, Flow phantom design
Therapeutic ultrasound discoveries: Sonoporation, Micro/nanobubble cavitation, Wave-matter interactions, Cellular dynamics studies
Centre for Bioengineering and Biotechnology
University of Waterloo, East Campus 4, Room 2001
200 University Avenue West
Waterloo , Ontario, N2L 3G1 Canada
cbb.uwaterloo.ca
519-888-4567 Ext 32732
The University of Waterloo acknowledges that much of our work takes place on the traditional territory of the Neutral, Anishinaabeg and Haudenosaunee peoples. Our main campus is situated on the Haldimand Tract, the land granted to the Six Nations that includes six miles on each side of the Grand River. Our active work toward reconciliation takes place across our campuses through research, learning, teaching, and community building, and is centralized within our Office of Indigenous Relations.