Our People - Targeted Drug Delivery

M. Aucoin
519-888-4567 x36084
Location: 
E6 4012

Research Interests:

  • Viral vector drug delivery

  • Biological nano-particles (Virus-Like Particles or VLPs)

  • Vaccines, gene therapy, gene expression, genetic diseases

  • Baculovirus Bioprocessing

  • Process dynamics of virus-based systems for the production of complex biologics such as viral vectors and vaccines

  • Development of strategies using multiple viruses to obtain recombinant products in cell culture

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[YouTube Lecture] September 30, 2014 "Tools and strategies for complex biologics production in animal cells: applications to insect and mammalian cell culture"

[YouTube] January 26, 2011 "Research Profile: Marc Aucoin"

Group(s): 
Application Areas→Infectious Diseases, Targeted Drug Delivery; Technology Areas→Cell Therapy, Gene Therapy, Therapeutics, Vaccines; Discipline Areas→Biology, Biomedical Engineering, Bionanotechnology, Bioprocessing/Biochemical Engineering, Biotechnology, Genetic Engineering, Nanotechnology; Faculty→Engineering
C. Burns
519-888-4567 x33903
Location: 
DWE 2508

Research Interests:

  • Ecological Interface Design
  • Cognitive Work Analysis
  • Graphical interface design and visualization
  • Healthcare systems and clinical diagnostic systems

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[CBB researcher story]

[Office of Research] May 22, 2018, CBB Executive Director reappointed for third term 

[YouTube] February 5, 2010 "Research Profile: Catherine Burns"

Group(s): 
Application Areas→Aging, Diabetes, Healthcare Systems, Targeted Drug Delivery, Wearable Devices; Technology Areas→Medical Devices; Discipline Areas→Human Factors; Faculty→Engineering
P. Chen
519-888-4567 x31197
Location: 
DWE 1511

Research Interests:

  • Nano-Biomedical engineering, biochemistry, molecular cell biology

  • Colloid and Surface Science (surface chemistry, absorption kinetics, thermodynamics)

  • Polymer materials, CO2

  • Energy storage and conversion, battery systems and alternative energy

  • Drug and gene delivery, genomics

  • Lipid bilayer and cell membrane actions

University Research Chair

Group(s): 
Application Areas→Targeted Drug Delivery; Technology Areas→Biomaterials, Imaging, Medical Devices, Polymer, Sensors; Discipline Areas→Bioprocessing/Biochemical Engineering, Biosystem Engineering, Biotechnology, Nanotechnology, Polymer Chemistry, Synthetic Biology; Faculty→Engineering; University Research Chairs
D. Edwards
519-888-4408 or x84408
Location: 
PHR 6002

Research Interests:

  • Effect of food, beverages, herbal products and other drugs on drug metabolism and disposition
  • Investigation of the interaction between grapefruit juice and prescription medication
  • pharmacokinetics
  • drug metabolism

  • pharmacogenomics

  • drug interactions

  • bioavailability/bioequivalence

LinkedIn

Group(s): 
Application Areas→Disease Modelling, Environmental Biotechnology, Neurodegenerative Diseases, Personalized Medicine, Targeted Drug Delivery; Technology Areas→Biomarkers, Biomaterials, Disease Modelling, Drug Development; Discipline Areas→Biomedical Engineering, Biomedicine, Pharmacology; Faculty→Science
F. Safa Erenay
519-888-4567 x32521
Location: 
CPH 4323

Research Interests:

  • Mathematical modeling - Stochastic Modeling and Optimization, Markov Decision Processes, Partially Observable Markov Decision Processes, Dynamic Programming, Simulation Models.
  • Health Care: Medical Decision Making, Organ Transplantation, Cancer Screening, Health Care Delivery.
  • Production Planning: Multicriteria Scheduling

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Research Gate

Google Scholar

Group(s): 
Application Areas→Cancer, Healthcare Systems, Targeted Drug Delivery; Technology Areas→Computational Modeling, Medical Devices; Discipline Areas→Biomedical Engineering, Biosystem Engineering, Biotechnology; Faculty→Engineering
M. Foldvari
519-888-4567 x21306
Location: 
PHR 3003

Research Interests:

  • Intelligent drug delivery system design (dermal, transdermal, transmucosal, ocular, and intranasal) for Dermatology, Ophthalmology, Cancer, Immunology (Glaucoma, neural degenerative disorders, HPV, LSIL/CIN I, cervical cancer, Scleroderma)

  • Non-invasive drug delivery technologies, biomolecular devices

  • Gene therapy, protein, and vaccine development

  • Nanomedicine, pharmaceutical development

  • Nanotoxicology (nanomaterials, bioimaging, biomarkers)

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ResearchGate

[Global Impact] [CBC] April 30, 2018 "Working with gene therapy to treat glaucoma"

[Waterloo Stories] July 5, 2012 "Revolutionary drug delivery"

Group(s): 
Application Areas→Infectious Diseases, Neurodegenerative Diseases, Optometry, Personalized Medicine, Targeted Drug Delivery; Technology Areas→Biomaterials, Drug Development, Gene Therapy, Imaging, Microfluids, Therapeutics, Vaccines; Discipline Areas→Biomedicine, Bionanotechnology, Biotechnology, Genetic Engineering, Nanotechnology, Regenerative Medicine, Stem Cell Engineering, Toxicology; Faculty→Science
Emmanuel Ho
519-888-4567 x21372
Location: 
PHR 4002

Research interests:

  • Imaging, treatment, and prevention of diseases
  • Fabrication and characterization of innovative biomaterials for drug delivery systems (nanoparticles, medical devices, biodegradable films, hydrogels, etc.)
  • Vaccine development for protection against HIV and other diseases

Google Scholar

[Waterloo News] February 6, 2019 "Researchers find new treatment for Chlamydia"

[Waterloo News] April 16, 2018 "Developing new way to fight transmission of HIV"

Group(s): 
Application Areas→Cancer, Disease Modelling, Infectious Diseases, Inflammatory Diseases, Pathogen Detection, Personalized Medicine, Targeted Drug Delivery, Wound Care; Technology Areas→3D Printing/Additive Manufacturing, Biomaterials, Disease Modelling, Gene Therapy, Medical Devices, Microfabrication, Polymer, Surface Coating, Vaccines; Discipline Areas→Biochemistry, Biomedical Engineering, Bionanotechnology, Biotechnology, Cell Biology, Chemistry, Nanotechnology, Pharmacology, Polymer Chemistry; Faculty→Science
J. Honek
519-888-4567 x35817
Location: 
ESC 246

Research Interests:

  • Methionine chemistry and biochemestry (amino acid methionine and its roles in proteins, cellular pathways and its functions)

  • Bionanomaterials, bionanotechnology (for novel drug carriers, molecular foundations for nanodevices)

  • Medicinal chemistry

  • Enzymology
  • Bioorganic chemistry
  • Protein structure and function

ResearchGate

[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners

Group(s): 
Application Areas→Cancer, Environmental Biotechnology, Industrial Biotechnology, Infectious Diseases, Targeted Drug Delivery, Toxicology; Technology Areas→3D Printing/Additive Manufacturing, Biomarkers, Biomaterials, Computational Modeling, Drug Development, Imaging, Polymer, Therapeutics; Discipline Areas→Biochemistry, Bioinformatics, Bionanotechnology, Biophysics, Bioprocessing/Biochemical Engineering, Biotechnology, Cell Biology, Chemistry, Genetic Engineering, Nanotechnology, Pharmacology, Polymer Chemistry, Toxicology; Faculty→Science
L.Jones
519-888-4065 or x84065
Location: 
OPT 360

Research Interests:

  • Clinical trial design
  • Contact lens performance
  • Drug delivery
  • Ocular biomaterials
  • Proteins at interfaces

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ResearchGate

Google Scholar

University Research Chair

Office of Research - Technology Transfer & Commercialization:

Group(s): 
Application Areas→Aging, Industrial Biotechnology, Optometry, Pathogen Detection, Personalized Medicine, Targeted Drug Delivery, Toxicology, Wearable Devices; Technology Areas→Biomarkers, Biomaterials, Diagnostics, Drug Development, Imaging, Medical Devices, Microbiome, Polymer, Sensors, Surface Coating, Therapeutics; Discipline Areas→Biochemistry, Biology, Biomedical Engineering, Biomedicine, Biophysics, Biotechnology, Cell Biology, Industrial Biotechnology, Nanotechnology, Pharmacology, Polymer Chemistry, Toxicology; Faculty→Science; University Research Chairs
Behrad Khamesee
519-888-4567 x35095
Location: 
E3 3148

Research Interests:

  • Smart structures, actuators, biomechanics, assistive devices, human-robot interaction, wearable sensors (fitness, monitoring, fall prevention, Alzheimer's)
  • Ophthalmic instrumentation, senors, technologies and hardware design (MRI, CT, ultrasound)
  • Micro-energy harvester through human locomotion
  • Magnetically driven medical microrobots for drug delivery and microsurgery
  • Regenerative prosthetic knee, and cost-effective prosthetic leg (structural design, sensory system, and controller)
  • Micromanipulation using magnetic levitation
  • Auto-focusing mechanism for microscopy using electrorestrictive
  • ​Clean room applications 

Google Scholar

[Waterloo Stories] August 28, 2018 "New sensor could help doctors monitor patient progress from a distance"

[Waterloo Stories] March 2, 2014 "Charge your phone while you shovel - and shiver"

Group(s): 
Application Areas→Rehabilitation, Targeted Drug Delivery, Wearable Devices; Technology Areas→Actuators, Medical Devices, Robotics, Sensors; Discipline Areas→Biomechanical Engineering, Biomedical Engineering, Mechanical and Mechatronics Engineering; Faculty→Engineering
Zoia Leonenko

Research Interests:

  • Biophysics of lipids and lipid-protein interactions

  • The role of structural changes and physical properties of lipid template in controlling biological processes and diseases

  • Biomedical nanotechnology (lipid films, molecular mechanism of Alzheimer's disease)

  • Drug development and delivery systems, antimicrobial peptides in lung disorders

  • Fluorescence and atomic force microscopy

  • Kelvin probe force microscopy and single molecule force spectroscopy

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[Global Impact] May 2018, studying Alzheimer's at a molecular level to find a cure

[YouTube Lecture] October 1, 2014 "Scanning probe microscopy in biomedical research"

Group(s): 
Application Areas→Aging, Diabetes, Disease Modelling, Environmental Biotechnology, Industrial Biotechnology, Infectious Diseases, Inflammatory Diseases, Mental Health, Neurodegenerative Diseases, Pathogen Detection, Personalized Medicine, Targeted Drug Delivery, Toxicology; Technology Areas→Biomaterials, Disease Modelling, Drug Development, Imaging, Medical Devices, Sensors, Surface Coating, Therapeutics, Vaccines; Discipline Areas→Biochemistry, Biology, Biomedical Engineering, Biomedicine, Bionanotechnology, Biophysics, Biotechnology, Cell Biology, Electrical and Computer Engineering, Environmental Biotechnology, Nanotechnology, Pharmacology, Physics, Polymer Chemistry, Toxicology; Faculty→Science
J. Liu
519-888-4567 x38919
Location: 
ESC 140

Research Interests:

  • Biomedical diagnosis

  • Targeted drug delivery

  • Environmental monitoring

  • DNA-based biosensors and functional polymers

  • Nanomaterials, (gold nanoparticles, liposomes, magnetic nanoparticles, quantum dots, graphene hydrogels, hybrid nanomaterials)

  • Bioinorganic / Bioanalytical chemistry

University Research Chair

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[Waterloo Stories] February 27, 2013 "Waterloo researcher uses nano-materials to clean water"

Group(s): 
Application Areas→Environmental Biotechnology, Targeted Drug Delivery; Technology Areas→Biomaterials, Diagnostics, Sensors; Discipline Areas→Biochemistry, Biomedical Engineering, Bionanotechnology, Biophysics, Chemistry, Nanotechnology; Faculty→Science; University Research Chairs
Tizazu Mekonnen
519-888-4567 X38914
Location: 
E6 5010

Research Interests:

  • Polymer Science and Engineering
  • Renewable polymers: Processing and Chemical Modifications
  • Polymer blends, composites and nanocomposites

Google Scholar

Group(s): 
Application Areas→Industrial Biotechnology, Targeted Drug Delivery; Technology Areas→3D Printing/Additive Manufacturing, Biomaterials, Polymer, Surface Coating; Discipline Areas→Bionanotechnology, Bioprocessing/Biochemical Engineering, Industrial Biotechnology, Polymer Chemistry; Faculty→Engineering
Parsin Haji Reza
519-888-4567 x40172
Location: 
E7 6416

Research Interests

  • Early Cancer Detection
  • Eliminating Positive Surgical Margins
  • Non-contact Biopsies for Endoscopy 
  • Functional Brain Imaging 
  • Early Detection and Understanding the Age-related Vision Loss Problems. 

[Website]

[Linkedin]

[Google Scholar]

Group(s): 
Application Areas→Cancer, Cardiovascular, Neurodegenerative Diseases, Optometry, Targeted Drug Delivery, Wound Care; Technology Areas→Biomarkers, Diagnostics, Imaging, Medical Devices; Discipline Areas→Biomedical Engineering, Biomedicine, Bionanotechnology, Biophysics, Bioprocessing/Biochemical Engineering, Biosystem Engineering, Biotechnology, Electrical and Computer Engineering, Nanotechnology, Physics; Faculty→Engineering
George Shaker
+1 519-498-5173
Location: 
E5 4126

Research Interests:

  • Bio-wearable electronics and systems
  • Bio-electromagnetics, bio-technology, bio-sensors and energy harvesting systems
  • RF/microwave/millimeter wave/Terahertz (THz) circuits and antenna systems
  • Radio frequency (RF)/microwave packaging and Electromagnetic compatibility 
  • (EMC)/Electromagnetic interface (EMI) analyses
  • Vehicle and UAV wireless communications, navigation systems, and telematics systems
  • Complex propagation and scattering phenomena
  • Devices and novel electromagnetic materials and wireless sensors

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ResearchGate

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[Waterloo News]  June 28, 2018 "AI and radar technologies could help diabetics manage their disease"

[Engineering News] June 28, 2018 "Researchers developing a prick-free glucose monitor"

[RD Magazine] June 28, 2018 "AI and Radar Technologies Could Help Diabetics Manage Their Disease

[Engineering News] July 5, 2016 "Waterloo wins big with tiny power device"

Group(s): 
Application Areas→Aging, Data Science, Diabetes, Environmental Biotechnology, Fall Prevention, Healthcare Systems, Industrial Biotechnology, Neurodegenerative Diseases, Optometry, Personalized Medicine, Rehabilitation, Space, Targeted Drug Delivery, Virtual Reality, Wearable Devices, Wound Care; Technology Areas→3D Printing/Additive Manufacturing, Actuators, Biomarkers, Biomaterials, Computational Modeling, Machine Learning/AI, Medical Devices, Sensors; Discipline Areas→Bioinformatics, Biomedical Engineering, Bionanotechnology, Biosystem Engineering, Biotechnology, Electrical and Computer Engineering, Industrial Biotechnology, Public Health, Robotics; Faculty→Engineering
R. Slavcev
519-888-4567 x21301
Location: 
PHR 4003

Research Interests:

  • Drug discovery, delivery systems and nanomedicine

  • Gene therapy, microbial genetics

  • Oncology, Antiviral therapeutics design

  • Anti-bacterials

  • Acne cosmeceutical design

  • Phage-based biotechnology

  • Viral exclusion systems

  • Cosmeceuticals

  • Vaccine design (dementia), bacteriophage-based biotechnology, use of coliphages to design and construct vectors for the development of novel vaccines, pharmaceuticals and gene delivery systems, and the identification and application of novel phage genomic anti-bacterial genes with potential phage therapy applications.

  • Strategic management in Pharmacy; healthcare reform

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ResearchGate

Group(s): 
Application Areas→Cancer, Healthcare Systems, Infectious Diseases, Neurodegenerative Diseases, Pathogen Detection, Targeted Drug Delivery; Technology Areas→Biomarkers, Gene Therapy, Therapeutics, Vaccines; Discipline Areas→Biochemistry, Biology, Biomedical Engineering, Biomedicine, Bionanotechnology, Biotechnology, Genetic Engineering, Genetics, Nanotechnology, Synthetic Biology; Faculty→Science
D. Spafford
519-888-4567 x38185
Location: 
B1 173

Research Interests:

  • Calcium channel analysis for target drug delivery for treatment of pain, arrhythmias, angina, and potential benefits in treatment of epilepsy and cancer.

  • Structure, function and pharmacology of calcium channels and sodium channels

  • Structure and function and analysis of NALCN cation channel  and anti-calcium channel toxins

  • The Spafford Neurobiology Research Laboratory studies voltage-gated calcium channels, molecular physiology, biophysics, cell biology, protein biochemistry, fluorescence microscopy and tissue cultures.

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[Science News] April 25, 2014 "Waterloo discovers a key regulator in the pacemakers of our brain and heart"

Group(s): 
Application Areas→Biomechanics, Cardiovascular, Neurodegenerative Diseases, Stroke, Targeted Drug Delivery; Technology Areas→Biomarkers, Computational Modeling, Disease Modelling, Drug Development, Imaging; Discipline Areas→Biochemistry, Biology, Biomedicine, Biophysics, Biotechnology, Cell Biology, Pharmacology, Physiology; Faculty→Science
Photo: M. Tam
519-888-4567 x38339
Location: 
E6 1010

Research Interests:

  • Enhanced drug delivery systems, gene therapy

  • Associative polymers for environmentally friendly coatings

  • Sustainable nanomaterials (cellulose nanocrystals)

  • Atom Transfer Radical Polymerization (ATRP) and stimuli responsive polymeric systems

  • Polymer-surfactant interactions

  • Magnetic nanoparticles for novel separation processes

University Research Chair

Google Scholar

Group(s): 
Application Areas→Environmental Biotechnology, Healthcare Systems, Targeted Drug Delivery; Technology Areas→3D Printing/Additive Manufacturing, Biomaterials, Polymer, Sensors, Surface Coating, Therapeutics; Discipline Areas→Bionanotechnology, Bioprocessing/Biochemical Engineering, Chemistry, Environmental Biotechnology, Nanotechnology, Polymer Chemistry; Faculty→Engineering; University Research Chairs
S.Tang
519-888-4567 x38037
Location: 
C2 279B

Research Interests:

  • Nanomaterials, nanodevices, biosensors for applications in food processing, bioreactors and biotechnology, natural gas purification, fuel cell, and water purification

  • Nano-Bio Hybrids for Tissue Engineering and Medicine for drug delivery, tissue engineering and regenerative medicine

  • Bio-molecule assisted nanomaterial self-assembly

  • Health and environmental effects of engineered nanomaterials

Group(s): 
Application Areas→Disease Modelling, Environmental Biotechnology, Targeted Drug Delivery; Technology Areas→Biomaterials, Diagnostics, Imaging, Medical Devices, Microfluids, Sensors, Therapeutics; Discipline Areas→Biology, Biomedical Engineering, Biomedicine, Bionanotechnology, Chemistry, Nanotechnology, Regenerative Medicine, Tissue Engineering; Faculty→Science
S.Taylor
519-888-4567 x33325
Location: 
C2 388

Research Interests:

  • Medicinal chemistry/enzymology (treatment of prostate and breast cancer, diabetes)

  • Nanomedicine; development of novel antibiotics

  • Bionanomaterials; synthetic polymers and methodologies

  • Peptide, charbohydrate, nucleoside and nucleotide chemistry

[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners

[Science News] February 4, 2015 "Chemists develop new method to improve the discovery of antibiotics"

Group(s): 
Application Areas→Cancer, Diabetes, Infectious Diseases, Targeted Drug Delivery, Wound Care; Technology Areas→Biomaterials, Drug Development, Polymer, Therapeutics; Discipline Areas→Biochemistry, Biomedicine, Bionanotechnology, Chemistry, Pharmacology, Polymer Chemistry, Synthetic Biology; Faculty→Science
S. Wettig
519-888-4567 x21303
Location: 
PHR 4011

Research Interests:

  • Gene therapy and drug delivery systems (prostate and ovarian cancer treatment)

  • Polymeric nanomaterials, biopolymers

  • Novel surface active compounds (gemini surfactants)

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[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners

[CBB researcher story] July 21, 2015 "Vectors for gene therapy and improving drug solubility"

Group(s): 
Application Areas→Cancer, Targeted Drug Delivery; Technology Areas→Biomaterials, Drug Development, Gene Therapy, Polymer, Surface Coating, Therapeutics; Discipline Areas→Bionanotechnology, Chemistry, Nanotechnology; Faculty→Science
Evelyn Yim
519-888-4567 x33928
Location: 
E6 4014

Research Interests:

  • Stem cells, nanofabrication and advancement of biomaterials in healthcare technologies to repair, replace or regenerate damaged tissue and organ structures

  • Fabrication and application of nano-structure for biomedical applications in neural, vascular, and cornea tissue engineering

  • ​Biomaterial approach to study ex-vivo pluripotent stem cell expansion

  • Modulation of cell behavior with nanotopography

  • Topography-regulation of stem cells lineage commitment and differentiation

  • Differentiation of adult and pluripotent stem cells with nanotopography

Google Scholar

Group(s): 
Application Areas→Cardiovascular, Disease Modelling, Neurodegenerative Diseases, Optometry, Personalized Medicine, Stroke, Targeted Drug Delivery; Technology Areas→Biomaterials, Cell Therapy, Disease Modelling, Medical Devices, Microfabrication, Polymer, Surface Coating, Therapeutics; Discipline Areas→Biomechanical Engineering, Biomedical Engineering, Biotechnology, Cell Biology, Nanotechnology, Regenerative Medicine, Stem Cell Engineering, Tissue Engineering; Faculty→Engineering
A.Yu
519-888-4567 x36908
Location: 
EIT 4125

Research Interests:

  • Ultrasound imaging innovations: Complex flow imaging, High-performance beamforming platforms, Flow phantom design

  • Therapeutic ultrasound discoveries: Sonoporation, Micro/nanobubble cavitation, Wave-matter interactions, Cellular dynamics studies

Google Scholar

Group(s): 
Application Areas→Aging, Cardiovascular, Stroke, Targeted Drug Delivery; Technology Areas→Diagnostics, Gene Therapy, Imaging, Medical Devices, Therapeutics; Discipline Areas→Biomedical Engineering, Biophysics; Faculty→Engineering

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