Our People - Cell Therapy

Research Interests:

• Viral vector drug delivery

• Biological nano-particles (Virus-Like Particles or VLPs)

• Vaccines, gene therapy, gene expression, genetic diseases

• Baculovirus Bioprocessing

• Process dynamics of virus-based systems for the production of complex biologics such as viral vectors and vaccines

• Development of strategies using multiple viruses to obtain recombinant products in cell culture

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[YouTube Lecture] September 30, 2014 "Tools and strategies for complex biologics production in animal cells: applications to insect and mammalian cell culture"

[YouTube] January 26, 2011 "Research Profile: Marc Aucoin"

Research Interests:

• cancer therapy
• colorectal, breast, prostate and lung carcinomas
• cancer tissue microenvironment
• chemokine pathways
• tumor-initiating cells
• proteins

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Research Gate

Research Interests:

• Research, in vitro toxicology, and biotechnology of animal cell cultures
• Roles of nutrition, hormones and polypeptide growth factors on the growth and differentiation of fish tissues and organs.

Research Interests:

• Chemical process control - Robust control, Nonlinear control, Model Predictive Control (MPC)

• Systems biology - modeling, control and optimization of biological processes, metabolic flux analysis, dynamic metabolic flux models, run-to-run (batch to batch) optimization of pharmaceutical process

• Monitoring/Fault Detection of chemical and biological/biotechnological processes - Multivariate statistical methods for monitoring and fault detection, Inferential (soft) sensors

Research Interests:

• Orthopaedic biomechanics (ACL, knee mechanics)

• Biomedical device design

• Tissue engineering

• Implant design

Research Interests:

• Bioinformatics tools (protein structures, genome mapping, conducting homology searches)

• Protein structure prediction, and automated NMR protein structure determination

• Stem cell image recognition

• Deep learning, natural language processing and automated conversation, AI

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Canada Research Chair in Bioinformatics [Canada Research Chair Profile]

The Royal Society of Canada Fellow

[Waterloo Stories] April 5, 2013 "RSVP: Responding to a need"

[Waterloo Stories] July 6, 2012 "Solving life's big issues, one question at a time"

Research interests:

• Neurodegeneration
• Huntington Disease
• Autophagy
• Apoptosis
• Fatty acylation

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Research Interests:

• Molecular genetics

• Cell and Developmental Biology

• Stem Cell Biology & Cellular Differentiation
• Programmed Cell Death
• Live-Imaging Microscopy

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Research Interests:

• Medical imaging (processing, registration, cell segmentation, tracking)
• Computer simulations (biomedical, brain and soft tissue injury and biomechanics, architectural, remote sensing, natural phenomena, fine arts)
• Computational finance
• Scientific computing (numerical solutions of partial differential equations, iterative methods, and multigrid preconditioning, parallel computation on high performance platforms)

Canada Research Chair in Scientific Computing [Canada Research Chair Profile]

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Research Interests:

• Stem cells, nanofabrication and advancement of biomaterials in healthcare technologies to repair, replace or regenerate damaged tissue and organ structures

• Fabrication and application of nano-structure for biomedical applications in neural, vascular, and cornea tissue engineering

• ​Biomaterial approach to study ex-vivo pluripotent stem cell expansion

• Modulation of cell behavior with nanotopography

• Topography-regulation of stem cells lineage commitment and differentiation

• Differentiation of adult and pluripotent stem cells with nanotopography

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