Marc Aucoin
Research Interests:
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Viral vector drug delivery
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Biological nano-particles (Virus-Like Particles or VLPs)
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Vaccines, gene therapy, gene expression, genetic diseases
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Baculovirus Bioprocessing
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Process dynamics of virus-based systems for the production of complex biologics such as viral vectors and vaccines
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Development of strategies using multiple viruses to obtain recombinant products in cell culture
[YouTube Lecture] September 30, 2014 "Tools and strategies for complex biologics production in animal cells: applications to insect and mammalian cell culture"
[YouTube] January 26, 2011 "Research Profile: Marc Aucoin"
Jonathan Blay
Research Interests:
- cancer therapy
- colorectal, breast, prostate and lung carcinomas
- cancer tissue microenvironment
- chemokine pathways
- tumor-initiating cells
- proteins
Niels Bols
Research Interests:
- Research, in vitro toxicology, and biotechnology of animal cell cultures
- Roles of nutrition, hormones and polypeptide growth factors on the growth and differentiation of fish tissues and organs.
Hector Budman
Research Interests:
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Chemical process control - Robust control, Nonlinear control, Model Predictive Control (MPC)
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Systems biology - modeling, control and optimization of biological processes, metabolic flux analysis, dynamic metabolic flux models, run-to-run (batch to batch) optimization of pharmaceutical process
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Monitoring/Fault Detection of chemical and biological/biotechnological processes - Multivariate statistical methods for monitoring and fault detection, Inferential (soft) sensors
Naveen Chandrashekar
Research Interests:
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Orthopaedic biomechanics (ACL, knee mechanics)
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Biomedical device design
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Tissue engineering
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Implant design
Ming Li
Research Interests:
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Bioinformatics tools (protein structures, genome mapping, conducting homology searches)
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Protein structure prediction, and automated NMR protein structure determination
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Stem cell image recognition
- Deep learning, natural language processing and automated conversation, AI
Canada Research Chair in Bioinformatics [Canada Research Chair Profile]
The Royal Society of Canada Fellow
[Waterloo Stories] April 5, 2013 "RSVP: Responding to a need"
[Waterloo Stories] July 6, 2012 "Solving life's big issues, one question at a time"
Bruce Reed
Research Interests:
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Molecular genetics
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Cell and Developmental Biology
- Stem Cell Biology & Cellular Differentiation
- Programmed Cell Death
- Live-Imaging Microscopy
Justin Wan
Research Interests:
- Medical imaging (processing, registration, cell segmentation, tracking)
- Computer simulations (biomedical, brain and soft tissue injury and biomechanics, architectural, remote sensing, natural phenomena, fine arts)
- Computational finance
- Scientific computing (numerical solutions of partial differential equations, iterative methods, and multigrid preconditioning, parallel computation on high performance platforms)
Canada Research Chair in Scientific Computing [Canada Research Chair Profile]
Evelyn Yim
Research Interests:
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Stem cells, nanofabrication and advancement of biomaterials in healthcare technologies to repair, replace or regenerate damaged tissue and organ structures
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Fabrication and application of nano-structure for biomedical applications in neural, vascular, and cornea tissue engineering
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Biomaterial approach to study ex-vivo pluripotent stem cell expansion
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Modulation of cell behavior with nanotopography
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Topography-regulation of stem cells lineage commitment and differentiation
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Differentiation of adult and pluripotent stem cells with nanotopography
