Javad Behravan
Research Interests
- Breast cancer, glioblastoma and acute lymphoblastic leukemia (ALL)
- Vaccine development
- Immunotherapy
- Phage based nanomedicine
Jonathan Blay
Research Interests:
- cancer therapy
- colorectal, breast, prostate and lung carcinomas
- cancer tissue microenvironment
- chemokine pathways
- tumor-initiating cells
- proteins
David Edwards
Research Interests:
- Effect of food, beverages, herbal products and other drugs on drug metabolism and disposition
- Investigation of the interaction between grapefruit juice and prescription medication
- pharmacokinetics
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drug metabolism
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pharmacogenomics
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drug interactions
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bioavailability/bioequivalence
Marianna Foldvari
Research Interests:
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Intelligent drug delivery system design (dermal, transdermal, transmucosal, ocular, and intranasal) for Dermatology, Ophthalmology, Cancer, Immunology (Glaucoma, neural degenerative disorders, HPV, LSIL/CIN I, cervical cancer, Scleroderma)
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Non-invasive drug delivery technologies, biomolecular devices
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Gene therapy, protein, and vaccine development
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Nanomedicine, pharmaceutical development
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Nanotoxicology (nanomaterials, bioimaging, biomarkers)
[Global Impact] [CBC] April 30, 2018 "Working with gene therapy to treat glaucoma"
[Waterloo Stories] July 5, 2012 "Revolutionary drug delivery"
Todd Holyoak
Research interests:
- GTP-dependent phosphoenolpyruvate carboxykinases
- IgA1 protease family of bacterial proteases
John Honek
Research Interests:
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Methionine chemistry and biochemestry (amino acid methionine and its roles in proteins, cellular pathways and its functions)
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Bionanomaterials, bionanotechnology (for novel drug carriers, molecular foundations for nanodevices)
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Medicinal chemistry
- Enzymology
- Bioorganic chemistry
- Protein structure and function
[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners
Lyndon Jones
Research Interests:
- Clinical trial design
- Contact lens performance
- Drug delivery
- Ocular biomaterials
- Proteins at interfaces
University Research Chair
Office of Research - Technology Transfer & Commercialization:
Zoya Leonenko
Research Interests:
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Biophysics of lipids and lipid-protein interactions
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The role of structural changes and physical properties of lipid template in controlling biological processes and diseases
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Biomedical nanotechnology (lipid films, molecular mechanism of Alzheimer's disease)
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Drug development and delivery systems, antimicrobial peptides in lung disorders
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Fluorescence and atomic force microscopy
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Kelvin probe force microscopy and single molecule force spectroscopy
[Global Impact] May 2018, studying Alzheimer's at a molecular level to find a cure
[YouTube Lecture] October 1, 2014 "Scanning probe microscopy in biomedical research"
John Mielke
Research interests:
- Neurobiological embedding of adversity
- Biological characteristics that influence outcome from brain injury
- Drug development, biomarkers
- Stroke; biological characteristics that influence outcomes from brain injury
Murray Young
Research Interests:
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Biopharmaceuticals (therapeutics, treatment of autoimmune diseases, prevent rejection of organ transplants)
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Industrial biomanufacturing and biotechnology (fermentation, food ingredients, enzymes, biofuels)
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Environmental management (bioremediation of carcinogenic environmental pollutants, filtration, chromatography)
The Royal Society of Canada Fellow
[YouTube Lecture] September 29, 2014 "Biofuels and Waste Treatment"
[YouTube Lecture] September 19, 2013 "Industrial Biotechnology: Current developments and trends"
[UW Eng-e-news] August 14, 2013 "Engineering Life-enhancing research"
[Waterloo Stories] May 3, 2013 "Can bacteria help create a cheaper fuel for our cars?"
[CBB researcher story] December 6, 2012 "Bringing Bioengineering and Biotechnology to its Fullest Potential"
Praveen Rao Perampalli Nekkar
Research Interests:
- Drug discovery
- Rational drug design and medicinal chemistry
- Cancer therapy
- Treatment of neurological disorders (Alzheimer's, Parkinson's)
- Drug discovery/rational design
- Synthesis and biological evaluation of novel organic molecules and peptides/peptidomimics as therapeutic agents
[Science News] October 22, 2018 "Nekkar lab determines that depression medications can help treat Alzheimer’s disease"
[Pharmacy News] July 29, 2015 "Waterloo pharmacist examines drug therapies for Alzheimer’s disease"
David Spafford
Research Interests:
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Calcium channel analysis for target drug delivery for treatment of pain, arrhythmias, angina, and potential benefits in treatment of epilepsy and cancer.
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Structure, function and pharmacology of calcium channels and sodium channels
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Structure and function and analysis of NALCN cation channel and anti-calcium channel toxins
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The Spafford Neurobiology Research Laboratory studies voltage-gated calcium channels, molecular physiology, biophysics, cell biology, protein biochemistry, fluorescence microscopy and tissue cultures.
[Science News] April 25, 2014 "Waterloo discovers a key regulator in the pacemakers of our brain and heart"
Scott Taylor
Research Interests:
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Medicinal chemistry/enzymology (treatment of prostate and breast cancer, diabetes)
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Nanomedicine; development of novel antibiotics
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Bionanomaterials; synthetic polymers and methodologies
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Peptide, charbohydrate, nucleoside and nucleotide chemistry
[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners
[Science News] February 4, 2015 "Chemists develop new method to improve the discovery of antibiotics"
Shawn Wettig
Research Interests:
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Gene therapy and drug delivery systems (prostate and ovarian cancer treatment)
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Polymeric nanomaterials, biopolymers
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Novel surface active compounds (gemini surfactants)
[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners
[CBB researcher story] July 21, 2015 "Vectors for gene therapy and improving drug solubility"
