Javad Behravan

Research Interests

  • Breast cancer, glioblastoma and acute lymphoblastic leukemia (ALL)
  • Vaccine development
  • Immunotherapy
  • Phage based nanomedicine

Google Scholar

Group(s): 
Application Areas→Cancer; Technology Areas→Drug Development, Therapeutics, Vaccines; Discipline Areas→Biochemistry, Biology, Bionanotechnology, Biotechnology, Cell Biology, Genetic Engineering, Immune Engineering, Nanotechnology, Pharmacology, Tissue Engineering; Faculty→Science
Jonathan Blay
519-888-4567 x21375
Location: 
PHR 3002

Research Interests:

  • cancer therapy
  • colorectal, breast, prostate and lung carcinomas
  • cancer tissue microenvironment
  • chemokine pathways
  • tumor-initiating cells
  • proteins

LinkedIn

Research Gate

Group(s): 
Application Areas→Cancer, Healthcare Systems; Technology Areas→Cell Therapy, Diagnostics, Drug Development, Gene Therapy; Discipline Areas→Biochemistry, Biology, Biomedical Engineering, Biotechnology, Cell Biology, Synthetic Biology; Faculty→Science
D. Edwards
519-888-4408
Location: 
PHR 6002

Research Interests:

  • Effect of food, beverages, herbal products and other drugs on drug metabolism and disposition
  • Investigation of the interaction between grapefruit juice and prescription medication
  • pharmacokinetics
  • drug metabolism

  • pharmacogenomics

  • drug interactions

  • bioavailability/bioequivalence

LinkedIn

Group(s): 
Application Areas→Disease Modelling, Environmental Biotechnology, Neurodegenerative Diseases, Personalized Medicine, Targeted Drug Delivery; Technology Areas→Biomarkers, Biomaterials, Disease Modelling, Drug Development; Discipline Areas→Biomedical Engineering, Biomedicine, Pharmacology; Faculty→Science
M. Foldvari
519-888-4567 x21306
Location: 
PHR 3003

Research Interests:

  • Intelligent drug delivery system design (dermal, transdermal, transmucosal, ocular, and intranasal) for Dermatology, Ophthalmology, Cancer, Immunology (Glaucoma, neural degenerative disorders, HPV, LSIL/CIN I, cervical cancer, Scleroderma)

  • Non-invasive drug delivery technologies, biomolecular devices

  • Gene therapy, protein, and vaccine development

  • Nanomedicine, pharmaceutical development

  • Nanotoxicology (nanomaterials, bioimaging, biomarkers)

LinkedIn

ResearchGate

[Global Impact] [CBC] April 30, 2018 "Working with gene therapy to treat glaucoma"

[Waterloo Stories] July 5, 2012 "Revolutionary drug delivery"

Group(s): 
Application Areas→Infectious Diseases, Neurodegenerative Diseases, Optometry, Personalized Medicine, Targeted Drug Delivery; Technology Areas→Biomaterials, Drug Development, Gene Therapy, Imaging, Microfluids, Therapeutics, Vaccines; Discipline Areas→Biomedicine, Bionanotechnology, Biotechnology, Genetic Engineering, Nanotechnology, Regenerative Medicine, Stem Cell Engineering, Toxicology; Faculty→Science
Aravindhan Ganesan
519-888-4567 x21325
Location: 
PHR 3010A

[Science Direct] August 10, 2018 "Revealing the atomistic details behind the binding of B7–1 to CD28 and CTLA-4: A comprehensive protein-protein modelling study"

[Nature] August 27, 2019 "Comprehensive in vitro characterization of PD-L1 small molecule inhibitors"

Group(s): 
Application Areas→Cancer, Diabetes, Neurodegenerative Diseases, Virtual Reality; Technology Areas→Computational Modeling, Drug Development, Therapeutics; Discipline Areas→Biochemistry, Bioinformatics, Biophysics; Faculty→Science
T. Holyoak
519-888-4567 x31559
Location: 
ESC 249

Research interests: 

  • GTP-dependent phosphoenolpyruvate carboxykinases
  • IgA1 protease family of bacterial proteases
Group(s): 
Application Areas→Cancer, Diabetes, Infectious Diseases, Inflammatory Diseases; Technology Areas→Computational Modeling, Drug Development, Imaging; Discipline Areas→Biochemistry, Bioinformatics, Biology, Biophysics; Faculty→Science
J. Honek
519-888-4567 x35817
Location: 
ESC 327

Research Interests:

  • Methionine chemistry and biochemestry (amino acid methionine and its roles in proteins, cellular pathways and its functions)

  • Bionanomaterials, bionanotechnology (for novel drug carriers, molecular foundations for nanodevices)

  • Medicinal chemistry

  • Enzymology
  • Bioorganic chemistry
  • Protein structure and function

ResearchGate

[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners

Group(s): 
Application Areas→Cancer, Environmental Biotechnology, Industrial Biotechnology, Infectious Diseases, Targeted Drug Delivery, Toxicology; Technology Areas→3D Printing/Additive Manufacturing, Biomarkers, Biomaterials, Computational Modeling, Drug Development, Imaging, Polymer, Therapeutics; Discipline Areas→Biochemistry, Bioinformatics, Bionanotechnology, Biophysics, Bioprocessing/Biochemical Engineering, Biotechnology, Cell Biology, Chemistry, Genetic Engineering, Nanotechnology, Pharmacology, Polymer Chemistry, Toxicology; Faculty→Science
L.Jones
519-888-4065
Location: 
OPT 228

Research Interests:

  • Clinical trial design
  • Contact lens performance
  • Drug delivery
  • Ocular biomaterials
  • Proteins at interfaces

LinkedIn

ResearchGate

Google Scholar

University Research Chair

Office of Research - Technology Transfer & Commercialization:

Group(s): 
Application Areas→Aging, Industrial Biotechnology, Optometry, Pathogen Detection, Personalized Medicine, Targeted Drug Delivery, Toxicology, Wearable Devices; Technology Areas→Biomarkers, Biomaterials, Diagnostics, Drug Development, Imaging, Medical Devices, Microbiome, Polymer, Sensors, Surface Coating, Therapeutics; Discipline Areas→Biochemistry, Biology, Biomedical Engineering, Biomedicine, Biophysics, Biotechnology, Cell Biology, Industrial Biotechnology, Nanotechnology, Pharmacology, Polymer Chemistry, Toxicology; Faculty→Science; University Research Chairs
Subha Kalyaanamoorthy photo
519-888-4567 x35804
Location: 
ESC 234

Research Interests:

  • Design/discovery of potential therapeutics to target various diseases
  • Understanding the structure and pharmacology of membrane proteins
  • Development of in silico methods/tools for sequence, structure and functional analysis
  • Inferring the structure-function evolution of proteins
  • Protein engineering for biotechnology and pharmaceutical applications

[American Chemical Society] January 23, 2012 "Exploring Inhibitor Release Pathways in Histone Deacetylases Using Random Acceleration Molecular Dynamics Simulations"

[Wiley Online Library] July 27, 2013 "Ligand release mechanisms and channels in histone deacetylases"

[Royal Society of Chemistry] December 19, 2013 "A steered molecular dynamics mediated hit discovery for histone deacetylases"

[Nature Methods] May 8, 2017 "ModelFinder: fast model selection for accurate phylogenetic estimates"

[Royal Society of Chemistry] October 24, 2017 "Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction"

Group(s): 
Application Areas→Cancer, Cardiovascular, Data Science, Industrial Biotechnology, Neurodegenerative Diseases, Stroke; Technology Areas→Biomaterials, Computational Modeling, Drug Development, Machine Learning/AI, Polymer, Therapeutics; Discipline Areas→Biochemistry, Bioinformatics, Biomedicine, Biophysics, Environmental Biotechnology, Industrial Biotechnology, Pharmacology, Synthetic Biology; Faculty→Science
Zoia Leonenko

Research Interests:

  • Biophysics of lipids and lipid-protein interactions

  • The role of structural changes and physical properties of lipid template in controlling biological processes and diseases

  • Biomedical nanotechnology (lipid films, molecular mechanism of Alzheimer's disease)

  • Drug development and delivery systems, antimicrobial peptides in lung disorders

  • Fluorescence and atomic force microscopy

  • Kelvin probe force microscopy and single molecule force spectroscopy

LinkedIn

ResearchGate

Google Scholar

[Global Impact] May 2018, studying Alzheimer's at a molecular level to find a cure

[YouTube Lecture] October 1, 2014 "Scanning probe microscopy in biomedical research"

Group(s): 
Application Areas→Aging, Diabetes, Disease Modelling, Environmental Biotechnology, Industrial Biotechnology, Infectious Diseases, Inflammatory Diseases, Mental Health, Neurodegenerative Diseases, Pathogen Detection, Personalized Medicine, Targeted Drug Delivery, Toxicology; Technology Areas→Biomaterials, Disease Modelling, Drug Development, Imaging, Medical Devices, Sensors, Surface Coating, Therapeutics, Vaccines; Discipline Areas→Biochemistry, Biology, Biomedical Engineering, Biomedicine, Bionanotechnology, Biophysics, Biotechnology, Cell Biology, Electrical and Computer Engineering, Environmental Biotechnology, Nanotechnology, Pharmacology, Physics, Polymer Chemistry, Toxicology; Faculty→Science
John Mielke
519-888-4567 x38843
Location: 
BMH 2107

Research interests: 

  • Neurobiological embedding of adversity
  • Biological characteristics that influence outcome from brain injury
  • Drug development, biomarkers
  • Stroke; biological characteristics that influence outcomes from brain injury

Google Scholar

Group(s): 
Application Areas→Stroke; Technology Areas→Biomarkers, Drug Development; Discipline Areas→Biochemistry, Biology, Biomedicine, Cell Biology, Pharmacology, Physiology, Public Health; Faculty→Applied Health Sciences
P. Nekkar
519-888-4567 x21317
Location: 
PHR 5002

Research Interests:

  • Drug discovery
  • Rational drug design and medicinal chemistry
  • Cancer therapy
  • Treatment of neurological disorders (Alzheimer's, Parkinson's)
  • Drug discovery/rational design
  • Synthesis and biological evaluation of novel organic molecules and peptides/peptidomimics as therapeutic agents

ResearchGate

Google Scholar

[Science News] October 22, 2018 "Nekkar lab determines that depression medications can help treat Alzheimer’s disease"

​[Pharmacy News] July 29, 2015 "Waterloo pharmacist examines drug therapies for Alzheimer’s disease"

Group(s): 
Application Areas→Aging, Cancer, Inflammatory Diseases, Neurodegenerative Diseases; Technology Areas→Biomarkers, Biomaterials, Computational Modeling, Diagnostics, Drug Development, Medical Devices, Therapeutics; Discipline Areas→Biochemistry, Biology, Biomedical Engineering, Biomedicine, Biophysics, Cell Biology, Chemistry, Pharmacology; Faculty→Science
D. Spafford
519-888-4567 x38185
Location: 
B1 172D

Research Interests:

  • Calcium channel analysis for target drug delivery for treatment of pain, arrhythmias, angina, and potential benefits in treatment of epilepsy and cancer.

  • Structure, function and pharmacology of calcium channels and sodium channels

  • Structure and function and analysis of NALCN cation channel  and anti-calcium channel toxins

  • The Spafford Neurobiology Research Laboratory studies voltage-gated calcium channels, molecular physiology, biophysics, cell biology, protein biochemistry, fluorescence microscopy and tissue cultures.

LinkedIn

ResearchGate

​Google Scholar

[Science News] April 25, 2014 "Waterloo discovers a key regulator in the pacemakers of our brain and heart"

Group(s): 
Application Areas→Biomechanics, Cardiovascular, Neurodegenerative Diseases, Stroke, Targeted Drug Delivery; Technology Areas→Biomarkers, Computational Modeling, Disease Modelling, Drug Development, Imaging; Discipline Areas→Biochemistry, Biology, Biomedicine, Biophysics, Biotechnology, Cell Biology, Pharmacology, Physiology; Faculty→Science
S.Taylor
519-888-4567 x33325
Location: 
C2 388

Research Interests:

  • Medicinal chemistry/enzymology (treatment of prostate and breast cancer, diabetes)

  • Nanomedicine; development of novel antibiotics

  • Bionanomaterials; synthetic polymers and methodologies

  • Peptide, charbohydrate, nucleoside and nucleotide chemistry

[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners

[Science News] February 4, 2015 "Chemists develop new method to improve the discovery of antibiotics"

Group(s): 
Application Areas→Cancer, Diabetes, Infectious Diseases, Targeted Drug Delivery, Wound Care; Technology Areas→Biomaterials, Drug Development, Polymer, Therapeutics; Discipline Areas→Biochemistry, Biomedicine, Bionanotechnology, Chemistry, Pharmacology, Polymer Chemistry, Synthetic Biology; Faculty→Science
S. Wettig
519-888-4567 x21303
Location: 
PHR 4012

Research Interests:

  • Gene therapy and drug delivery systems (prostate and ovarian cancer treatment)

  • Polymeric nanomaterials, biopolymers

  • Novel surface active compounds (gemini surfactants)

LinkedIn

ResearchGate

Google Scholar

[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners

[CBB researcher story] July 21, 2015 "Vectors for gene therapy and improving drug solubility"

Group(s): 
Application Areas→Cancer, Targeted Drug Delivery; Technology Areas→Biomaterials, Drug Development, Gene Therapy, Polymer, Surface Coating, Therapeutics; Discipline Areas→Bionanotechnology, Chemistry, Nanotechnology; Faculty→Science
M. Moo-Young
519-888-4006
Location: 
E6 1008

Research Interests:

  • Biopharmaceuticals (therapeutics, treatment of autoimmune diseases, prevent rejection of organ transplants)

  • Industrial biomanufacturing and biotechnology (fermentation, food ingredients, enzymes, biofuels)

  • Environmental management (bioremediation of carcinogenic environmental pollutants, filtration, chromatography)

The Royal Society of Canada Fellow

[YouTube Lecture] September 29, 2014 "Biofuels and Waste Treatment"

[YouTube Lecture] September 19, 2013 "Industrial Biotechnology: Current developments and trends"

[UW Eng-e-news] August 14, 2013 "Engineering Life-enhancing research"

[Waterloo Stories] May 3, 2013 "Can bacteria help create a cheaper fuel for our cars?"

[CBB researcher story] December 6, 2012 "Bringing Bioengineering and Biotechnology to its Fullest Potential"

Group(s): 
Application Areas→Environmental Biotechnology, Industrial Biotechnology; Technology Areas→Biomaterials, Computational Modeling, Drug Development, Polymer, Therapeutics, Vaccines; Discipline Areas→Biochemistry, Bioprocessing/Biochemical Engineering, Biosystem Engineering, Biotechnology, Environmental Biotechnology, Genetic Engineering, Industrial Biotechnology, Physics, Polymer Chemistry, Synthetic Biology, Tissue Engineering; Faculty→Engineering; The Royal Society of Canada Fellows
Madjid Soltani
Group(s): 
Application Areas→Cancer, Cardiovascular, Data Science, Disease Modelling, Environmental Biotechnology, Industrial Biotechnology, Optometry, Personalized Medicine, Rehabilitation, Wearable Devices, Wound Care; Technology Areas→Computational Modeling, Diagnostics, Disease Modelling, Drug Development, Imaging, Machine Learning/AI, Medical Devices, Microfabrication, Microfluids; Discipline Areas→Bioinformatics, Biomechanical Engineering, Biomedical Engineering, Biomedicine, Bionanotechnology, Biophysics, Biosystem Engineering, Biotechnology, Computer Science, Electrical and Computer Engineering, Environmental Biotechnology, Kinesiology, Mechanical and Mechatronics Engineering, Nanotechnology, Pharmacology, Public Health, Regenerative Medicine, Tissue Engineering; Faculty→Engineering

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