Our People - Imaging

Research Interests:

• Biomechanical properties of soft tissues
• Integration of imaging and mechanics
• Biomechanical-based image registration for surgery and radiotherapy
• Mechanics and structural applications of composite materials
• Smart devices and sensors

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​Research Gate

[YouTube Lecture] September 30, 2014 "An engineering prospective on Cancer'

Research Interests:

• Quantum devices (High and low Tc tunnel devices, nanobiotechnology-based devices)
• Biomedical engineering, MEMS/MOEMS and CMOS integration
• Lab on chip, medical diagnostic and microfluidic devices
• Remote sensing and radio astronomy

Research Interests:

• Multisensory integration
• Perception and action
• Psychophysics
• The vestibular system
• Virtual reality

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[Waterloo News] September 25, 2018 "Virtual reality motion sickness may be predicted and counteracted"

[ScienceDaily] December 15, 2018 "Aging warps our perception of time, study finds"

[Record] October 12, 2017 "Aging slows perception of falls: UW study"

Research Interests:

• Solid-state electron and nuclear spin based implementations for quantum information processing (QIP)
• Spin qubits in quantum dots
• Low temperature quantum transport
• Nanowires and novel materials
• Coherent control of quantum systems
• Electron and nuclear magnetic resonance spectroscopies

• Infrared imaging technology

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[Waterloo Stories] September 29, 2013 "Waterloo researcher loves the hands-on side of quantum science"

Research Interests:

• Treatment of neurological disorders (Alzheimer’s, Parkinson’s, and mental health conditions including schizophrenia and depression)

• Molecular pharmacology and pharmaceutical delivery

• Intracellular signaling pathways in neurons, and the role of cytoskeletal dynamics in the trafficking of receptors in neurons

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Research Interests:

• Biomedical optics

• Tissue optics and spectroscopy

• Ultrafast optics, coherence tomography, sensing, imaging

• Confocal and fluorescence microscopy

• Skin cancer detection

• Atomic, Molecular and Optical Physics

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Research Gate

Research Interests:

My research program combines a fundamental in-vitro research approach, examining the time varying response of the lumbar spine tissues, with in-vivo human research, examining biological responses to cumulative loading exposure from both pain generating and tissue altering/injuring perspectives. Work in my laboratories involves developing approaches to assess workplace cumulative loading exposure and injury in conjunction with in-vitro tissue mechanics studies investigating the injury pathways from repetitive loading. Currently, quantifying the influence of modifiers such as repetition and magnitude of exposure to establish the relationship between cumulative loading and low back pain is a major focus in my research. This knowledge will complement existing epidemiological data, linking cumulative loading and low back pain, for setting exposure limits and helping to prevent low back injuries.

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Research Interests:

• Imaging for Type 1 Diabetes
• Alzheimer Diagnosis
• Imaging of the Rear of the Eye
• Optical Properties of the Eye amd changes in the Eye's Optical Properties
• Two Photon Therapies
• Ophthalmic instrumentation, optical systems, quality and design

• Confocal microscopy and ophthalmoscopy, measurement of refractive error

• Retinal image quality

• Optical effects of refractive surgery, reflections from the retina

• Optical properties of the eye, monochromatic aberrations of the eye

• Refractive properties of the crystalline lens and their changes with growth and accommodation

• Eye-imaging systems for treatment and diagnosis

• Biophysics, bio-photonics, and Vision Science.

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[Research2Reality] May 8, 2015 "Early Alzheimer's Diagnosis: Imaging the Living Eye"

[YouTube Lecture] October 1, 2014 "Optics of the Eye as a Window on the Brain"

[YouTube] February 12, 2013 "Melanie Campbell AAAS Profile"

[Waterloo Stories] February 12, 2013 "An early test for Alzhemer's disease"

[Waterloo Stories] January 22, 2013 "Early test for Alzheimer's may rely on the eyes"

Office of Research - Technology Transfer & Commercialization:

• Imaging Amyloid Beta in the Retina
• Ophthalmic and Microscopy Imaging Technology

Research Interests:

• Nano-Biomedical engineering, biochemistry, molecular cell biology

• Colloid and Surface Science (surface chemistry, absorption kinetics, thermodynamics)

• Polymer materials, CO2

• Energy storage and conversion, battery systems and alternative energy

• Drug and gene delivery, genomics

• Lipid bilayer and cell membrane actions

University Research Chair

Research Interests:

• Biomedical and scientific imaging

• Computer vision and video analysis

• Image processing, segmentation/classification

• Multiresolution techniques

• Automated interpretation of SAR (synthetic aperture radar)

• Remote sensing

• Stochastic models

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[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners

[The Record] May 8,2018, have ties with a new Montreal sports analytics research lab in Kitchener

Research Interests

• Cognitive Neuroscience
• Boredom
• Mental Health 
• Neuroimaging 

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CBB Executive Director

Research Interests:

• Fundamental shoulder function and dysfunction
• Creation and validation of mathematical models to predict shoulder demands
• Applications of shoulder biomechanics to workplace injury prevention
• Rehabilitative and preventative strategies for ensuring shoulder health
• Digital human modeling, Computational musculoskeletal modeling
• Ergonomics
• Motion Capture
• Upper limb biomechanics

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Canada Research Chair in Shoulder Mechanics [Canada Research Chair Profile]

[Waterloo News] February 19, 2019 "How to make the push-up work for you" 

[Waterloo Stories] October 7, 2013 "Reducing shoulder injuries in the workplace"

Research Interests:

• Computer vision, signal and image processing

• Remote sensing

• Intelligent systems and software

• Multiscale statistical modeling

• Societal and environmental systems

LinkedIn

​[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners

Research Interests:

• Intelligent drug delivery system design (dermal, transdermal, transmucosal, ocular, and intranasal) for Dermatology, Ophthalmology, Cancer, Immunology (Glaucoma, neural degenerative disorders, HPV, LSIL/CIN I, cervical cancer, Scleroderma)

• Non-invasive drug delivery technologies, biomolecular devices

• Gene therapy, protein, and vaccine development

• Nanomedicine, pharmaceutical development

• Nanotoxicology (nanomaterials, bioimaging, biomarkers)

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ResearchGate

[Global Impact] [CBC] April 30, 2018 "Working with gene therapy to treat glaucoma"

[Waterloo Stories] July 5, 2012 "Revolutionary drug delivery"

Research interests:

• Public Health - access to care and healthcare system efficiency
• Telehealth - remote delivery of healthcare locally and globally
• Health Informatics – use of AI and machine learning to optimize the diagnosis and management of ocular disease
• Ocular Disease & Ophthalmic Imaging
• Interprofessional Education and Collaboration

Research Interests:

• Osteoporosis, fracture risk assessment algorithms, exercise interventions for reducing fracture risk in high risk individuals.

• Bone health and body composition in individuals with neurological impairment due to spinal cord injury (SCI).

• Medical imaging analysis to explore bone and muscle responses to activity or neurologic impairment, and evaluate new methods for image analysis.

• Rehabilitation and quality indicators, and in long term care

Schlegel Research Chair in Mobility & Aging

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Research interests:

• Brain Health
• Social neuroscience of eating 
• Social neuroscience of addictions and mental health 

• Mobile brain imaging technology

• Neuromodulation techniques

Podcast: Developing new ways of quantifying brain health using magnetic brain stimulation paradigms; this involves using brain stimulation for diagnostic assessment rather than the conventional usage in therapeutics.

Recent Publications: https://uwaterloo.ca/prevention-neuroscience-lab/recent-publications

Research interests: 

• GTP-dependent phosphoenolpyruvate carboxykinases
• IgA1 protease family of bacterial proteases

Research Interests:

• Methionine chemistry and biochemestry (amino acid methionine and its roles in proteins, cellular pathways and its functions)

• Bionanomaterials, bionanotechnology (for novel drug carriers, molecular foundations for nanodevices)

• Medicinal chemistry

• Enzymology
• Bioorganic chemistry
• Protein structure and function

ResearchGate

[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners

Research interests:

• Cellular-scale retinal imaging and light safety for the eye.
• Pioneer of two-photon excited fluorescence imaging through the pupil of a living primate eye, which enabled my group to be the first to image translucent primate retinal ganglion cells in vivo.
• First to deploy in vivo fluorescence lifetime imaging ophthalmoscopy of the retina at the cellular scale in living human and non-human primate eyes.

Research Interests:

• Clinical trial design
• Contact lens performance
• Drug delivery
• Ocular biomaterials
• Proteins at interfaces

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ResearchGate

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University Research Chair

Office of Research - Technology Transfer & Commercialization:

• Long-lasting Eye Drop Delivery Platform for Targeted Ocular Delivery Applications

Research Interests:

• Low-dose, low-cost x-ray imaging system (e.g. tuberculosis screening)

• Circuit technology, Photon counting circuits for biomedical imaging

• Large area digital medical imaging

• Silicon Thin-film Applied Research

• Device physics

• Amorphous semiconductors and semiconductor devices

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[Engineering News] November 12, 2018 "New X-ray technology to be tested on cancer patients"

[YouTube Lecture] September 30, 2014 "Bending the cost curve: Building a $1000 diagnostic X-ray imager for scalable and sustainable healthcare"

[Office of Research] "Paving the way for a digital X-ray and health-care revolution"

Research interests:

• Upper-extremity biomechanics 
• Orthopaedic biomechanics 
• Osteoarthritis
• Computational modeling 
• Imaging

[Google scholar profile]

Research Interests:

• Biomedical systems & biomechatronics - rehabilitation, assistive devices, intelligent design of prostheses and orthoses, 3D body surface measurement
• Optomechatronics - computer vision (2D and 3D), range-image registration, range-sensing, range-sensor design, vision-based 3D surface measurement systems, optical system design, laser-camera range, sensor design, phase-shifting / fringe-projection 3D surface measurement systems, real-time full-field 3D imaging sensors / real-time full-field 3D surface measurement systems, hand-held 3D imaging sensors / hand-held 3D surface measurement systems, vision-based robot control, vision-based human-robot interfaces
• Robotics - robot teleoperation, robot vision, human-robot interfaces, human-robot interaction, human-guided robot learning, vision-based robot control (visual servoing), human-assistive/service robots

Office of Research - Technology Transfer & Commercialization:

• Real-Time Full-Field 3D Shape Measurement

Research Interests:

• Classical and visual optics
• Optical system design, science and engineering
• Psychophysics/human factors
• Visual perception, visual optics math modelling
• Biomedical image processing

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[CBB researcher story] July 29, 2015 "Image processing to automate early glaucoma diagnosis"

Research Interests:

• Biophysics of lipids and lipid-protein interactions

• The role of structural changes and physical properties of lipid template in controlling biological processes and diseases

• Biomedical nanotechnology (lipid films, molecular mechanism of Alzheimer's disease)

• Drug development and delivery systems, antimicrobial peptides in lung disorders

• Fluorescence and atomic force microscopy

• Kelvin probe force microscopy and single molecule force spectroscopy

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[Global Impact] May 2018, studying Alzheimer's at a molecular level to find a cure

[YouTube Lecture] October 1, 2014 "Scanning probe microscopy in biomedical research"

Research Interests:

• Integrated microsystems for clinical and environmental monitoring

• Combining complementary metal-oxide-semiconductor (CMOS) integrated circuits with novel materials, structures, or devices to enable non-traditional life science and bio-diagnostic applications

• CMOS-integrated biochemical assays

• Semiconductor integrated circuits and sensors, design and test of 3D integrated circuits

• Micro/nano fabrication, lab-on-a-chip devices

• Electrochemical biosensors

• Electrophysiology

• DNA sequencing

• Image sensors

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Research Interests:

Development of organic materials and nanomaterials for printed and organic optical and electronic devices

• Environmentally stable polymer semiconductors for biological and chemical sensors in applications in smart food packaging, health care devices, wearable electronics, etc.
• Polymers derived from biologically active compounds for biological and biochemical sensors
• Electrically highly conductive polymers for thermoelectrics, batteries, and solar cells
• Low-temperature processable metal nanoparticle conductive inks
• P-type and n-type high charge carrier mobility small molecules and p-conjugated polymers for organic field effect transistors, which have applications in RFIDs and displays
• Novel synthetic chemistry for conjugated polymers
• Single-walled carbon nanotubes and graphene

Design, fabrication, and characterization of organic electronics

• Chemical/biosensors​
• Organic thin film transistors (OTFTs) or organic filed effect transistors (OTFTs)
• Small molecule and polymer bulk-heterojunction photovoltaics (OPV) (solar cells)
• Dye-sensitized solar cells (DSC)
• Perovskite solar cells
• Organic light-emitting diodes (OLEDs)
• Photodiode and phototransistor based organic/polymer photodetectors

​Office of Research - Technology Transfer & Commercialization:

• N-Type Organic Semiconductor Formulations, Devices

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Patents

Research Interests:

• Bioinformatics tools (protein structures, genome mapping, conducting homology searches)

• Protein structure prediction, and automated NMR protein structure determination

• Stem cell image recognition

• Deep learning, natural language processing and automated conversation, AI

Google Scholar

Canada Research Chair in Bioinformatics [Canada Research Chair Profile]

The Royal Society of Canada Fellow

[Waterloo Stories] April 5, 2013 "RSVP: Responding to a need"

[Waterloo Stories] July 6, 2012 "Solving life's big issues, one question at a time"

Research Interests:

• Medical device and diagnostic development for hearing and hearing loss
• Audiology and Otolaryngology
• Acoustic, Vibration, physiological and cadaveric measurements, animal models
• Aging, Biomechanics

Research interests:

• Aging and neurodegeneration
• Movement disorders
• Gait kinematics
• Neuropsychology and neurocognitive assessment
• Mood, emotion and cognition
• Fear, threat, anxiety and depression
• Virtual reality

Google Scholar

Research interests:

• Neurodegeneration
• Huntington Disease
• Autophagy
• Apoptosis
• Fatty acylation

Google Scholar

Research Interests:

• Neuroscience and neurological disorders
• Balance, gait, exercise
• Aging
• Understanding how the brain and other parts of the central nervous system control movements of the body
• Using advanced measurements systems to improve recovery time after a neurological injury (such as a stroke) and minimize age-related effects on movement control (such as reducing the risk of falling). 
• Electroencephalography and electromyography
• Transcranial magnetic stimulation, magnetic resonance imaging, peripheral nerve stimulation
• Galvanic skin measurement
• Eye-tracker, motion analysis, and kinetic measurement

Google Scholar

[Waterloo News] August 19, 2015 "Wearable technologies will improve stroke rehabilitation"

[Waterloo Stories] February 4, 2014 "Finding your way after a stroke"

Research interests:

• Medical devices relating to orthopaedic surgery
• Aging, biomechanics, personalized medicine, virtual reality, wearable devices, surgical navigation
• 3D printing/additive manufacturing, actuators, computational modelling, imaging, medical devices

Google Scholar

Research Interests:

My research focuses on brain plasticity and the neural control of movement. I utilize non-invasive methods, like transcranial magnetic stimulation (TMS) and electroencephalography (EEG), to study the neural correlates of performance and skill learning in healthy and clinical populations. In particular, my current focus is centred upon how different brain systems underlying motor control/learning interact to determine brain plasticity with an emphasis on enhancing stroke rehabilitation.

Research Gate

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Research Interests:

•  design and control of spinal exoskeletons for he prevention of back pain
•  development of assistive robotic devices to increase mobility of older person
•  design studies of lower limb exoskeletons

Research interests:

• Development of a thermal imaging system for the ocular surface
• Development of a tear evaporation sensing and measurement system
• Development of an ocular surface sensory neuroscience testing system
  
   

Research Interests:

• Role of normal binocular vision in the development of fine motor skills
• Neuroplasticity resulting from abnormal binocular vision due to amblyopia and/or strabismus
• Multisensory integration during performance of complex manipulation tasks
• Gaze behaviour in complex environments
• Innovative assessment of pilot competency
• Effect of mild traumatic brain injury and post-concussion syndrome on oculomotor and cognitive functions
• Environmental and genetic interactions

Research interests:

[Science Mag] June 6, 2016 "This desert moss can water itself with fog"

[Nature] June 08, 2016 "How desert moss drinks from air"

[PNAS] June 22, 2017 "Cavitation onset caused by acceleration"

Research Interests:

• RNA Biology
• Cell Biology
• Molecular Genetics
• Developmental Biology

Research Interests:

• Biomedical applications of electromagnetics

• Electromagnetic compatibility, interference, propagation mechanisms

• Material measurements, metamaterials and its engineering applications

• Energy harvesting

• Surface and subsurface detection using near-field microscopy

• Electronic packaging

• Photonics

• Radiating systems, theoretical and computational electromagnetics

Research Gate

Google Scholar

Research Interests:

• Molecular genetics

• Cell and Developmental Biology

• Stem Cell Biology & Cellular Differentiation
• Programmed Cell Death
• Live-Imaging Microscopy

Google Scholar

Research Interests:

• Protein and DNA separation analysis towards disease diagnosis and drug discovery

• Biosensing and Devices (bacterial, proteins, fluorescence)

• Living cell analysis and water toxicity testing

• Lab-on-a-Chip technology (point-of-care biomedical diagnosis , chemical detection, protein separation and identification, environmental testing)

• Micro-scale fluid mechanics, droplet microfluidics and nanofluidics

• High Throughput Screening For Drug Screening
• Manufacturing Nanomaterials and Carbon Management

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Canada Research Chair in Lab-on-a-Chip Technology [Canada Research Chair Profile]

[Waterloo Stories] June 14, 2012 "Creating the tiny future of science"

Research Interests

• Early Cancer Detection
• Eliminating Positive Surgical Margins
• Non-contact Biopsies for Endoscopy 
• Functional Brain Imaging 
• Early Detection and Understanding the Age-related Vision Loss Problems
• Wound Care
• Cardiovascular
• Machine learning/AI

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[Google Scholar]

Research Interests:

• Calcium channel analysis for target drug delivery for treatment of pain, arrhythmias, angina, and potential benefits in treatment of epilepsy and cancer.

• Structure, function and pharmacology of calcium channels and sodium channels

• Structure and function and analysis of NALCN cation channel  and anti-calcium channel toxins

• The Spafford Neurobiology Research Laboratory studies voltage-gated calcium channels, molecular physiology, biophysics, cell biology, protein biochemistry, fluorescence microscopy and tissue cultures.

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[Science News] April 25, 2014 "Waterloo discovers a key regulator in the pacemakers of our brain and heart"

Research Interests:

• Electrophysiological characterization of neuromuscular disorders

• Autonomous and knowledge systems

• Machine perception and sensors

• Image processing and analysis, pattern analysis and recognition

• EMG signal decomposition, simulation and quantitative EMG and DQEMG

• Biomedical engineering

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Research Interests:

• Nanomaterials, nanodevices, biosensors for applications in food processing, bioreactors and biotechnology, natural gas purification, fuel cell, and water purification

• Nano-Bio Hybrids for Tissue Engineering and Medicine for drug delivery, tissue engineering and regenerative medicine

• Bio-molecule assisted nanomaterial self-assembly

• Health and environmental effects of engineered nanomaterials

Research Interests

• human visual cortex development and plasticity
• videogames for vision rehabilitation (amblyopia)
• vision loss treatments and rehabilitation
• diagnostics
• imaging

Research Gate

Google Scholar

[YouTube] February 13, 2019 "Teaching an old brain new tricks" TEDxUW

Research Interests:

• Tissue engineering and biodegradable implants for regenerative medicine (3D printing)

• Bio-additive and microscale-additive manufacturing (opto-mechanical sensors, smart structures, developed through additive manufacturing)

• Novel multi-scale additive manufacturing technologies for biomedical, oil/gas and manufacturing sectors

• Laser-based fabrication techniques with particular focus on direct write processes in micro- and macro-scale

• Modeling, sensing and real-time control of laser-based manufacturing techniques

University Research Chair

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​Canada Research Chair in Multi-Scale Additive Manufacturing  [Canada Research Chair Profile]

[Office of Research News] May 8,2018 "Waterloo researchers named Canada Research Chairs" 

[YouTube Lecture] May 6, 2014 "Additive manufacturing"

Office of Research - Technology Transfer & Commercialization:

• 3D Variable Density Printing
• Graphene Printing
• Dual-Parameter Fiber Optic Sensor

Research Interests:

• Rehabilitation engineering and assistive technologies (gerontology, Osteoporosis, Alzheimer’s disease, fall risk in stroke survivors, and rehabilitation following traumatic brain injury)

• Neuromotor control

• Biomedical signal analysis

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​Google Scholar

[Waterloo Stories] July 8, 2014 "GPS technology may help detect Alzheimer’s disease earlier"

Research Interests:

• Medical imaging (processing, registration, cell segmentation, tracking)
• Computer simulations (biomedical, brain and soft tissue injury and biomechanics, architectural, remote sensing, natural phenomena, fine arts)
• Computational finance
• Scientific computing (numerical solutions of partial differential equations, iterative methods, and multigrid preconditioning, parallel computation on high performance platforms)

Canada Research Chair in Scientific Computing [Canada Research Chair Profile]

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Research Interests:

• Image and signal processing, coding and quality assessment
• Computational vision and pattern analysis
• Multimedia communications
• Biomedical signal and image processing

The Royal Society of Canada Fellow

University Research Chair

Google Scholar

[Waterloo News] October 5, 2015 "Waterloo Engineer wins Emmy Award"

[Waterloo Stories] February 3, 2014 "Engineering professor awarded prestigious fellowship"

Office of Research - Technology Transfer & Commercialization:

• High Performance Video Compression

Research Interests:

• Biomaterials and mechanics of biomaterials and tissues

• Bone quality and fragility, collagen

• Engineering of bone mimetic materials for skeletal reconstruction (3D printing)

Google Scholar

Research Interests:

• Biomedical image processing and analysis (prostate, breast, lung and dermatological cancer analysis, retinal photoreceptor and blood vessel analysis, musculoskeletal kinematic analysis

• Remote sensing data processing and analysis (sea ice, underwater object, oil spill analysis)

• Perceptual based video and image processing (noise reduction, compression, enhancement)

• Computer vision and pattern recognition

• Multimedia management systems

• 3D graphics and game development

• Cognitive radio networks

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Canada Research Chair in Medical Imaging Systems [Canada Research Chair Profile]

[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners

[Waterloo News] [CBC News] [Gadgets] May 16, 2018, Co-authors discuss the use of aerobic fitness data from wearable tech to predict illness

[Waterloo News] May 15, 2018 "Researchers combine wearable technology and AI to predict the onset of health problems"

[Global Impact] [570 news] [Youtube] April 11, 2018 "How AI is helping doctors diagnose Cancer" 

[The Star] February 9, 2018 "How TheRedPin aims to take a swipe at the real estate industry"

[Waterloo News] June 7, 2017 "Artificial intelligence-driven imaging research makes diagnosing disease easier"

[Waterloo Stories] January 28, 2017 "Artificial intelligence and the Waterloo-Toronto tech supercluster"

[Waterloo Stories] May 20, 2016 "Breakthrough tech helps doctors more accurately diagnose cancer"

[CBB researcher story] January 9, 2013 "Improving Early Diagnosis to Save Lives"

[Waterloo Stories] January 9, 2013 "Making it harder for cancer to hide"

[YouTube Lecture] October 1, 2014 "Integrative systems for biomedical imaging and analysis"

Research interests:

• Vision rehabilitation
• Systems for optimizing patient care outcomes
• Retinal disease
• Pharmacology.

Research interests:

Research Interests:

• Ultrasound imaging innovations: Complex flow imaging, High-performance beamforming platforms, Flow phantom design

• Therapeutic ultrasound discoveries: Sonoporation, Micro/nanobubble cavitation, Wave-matter interactions, Cellular dynamics studies

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