Our People - Microbiome

Research Interests:

• Bacterial molecular genetics

• Functional genomics, metagenomics, genome engineering

• Metabolic functions

• Synthetic biology, bioplastics and bioproducts

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[Biology News] December 21, 2016 "Waterloo biologist part of a research collaboration creating new genetic toolbox"

[Royal Canadian Institute Lecture] November 8, 2015 "Genome Engineering. Should we do it? (Can we afford not to?)"

[YouTube Lecture] September 30, 2014 "Mining microbial metagenomes"

[YouTube Lecture] September 19, 2013 "Mining metagenomes for bioplastics and other useful bioproducts"

[CBB researcher story] November 29, 2012 "Breaking Ground in Open Resource Metagenomics"

Research Interests:

• Biochemical engineering

• Microbial biotechnology

• Synthetic and molecular biology

• Genetic, metabolic and protein engineering

• Biopharmaceuticals (to treat autoimmune diseases and prevent rejection of organ transplants)

• Biomanufacturing, bioprocessing technologies (biological strain construction, bioreaction cultivation, biofuels, bioproduct recovery and purification)

[Waterloo Stories] May 3, 2013 "Can bacteria help create a cheaper fuel for our cars?"

[UW Eng-e-news] August 14, 2013 "Engineering Life-enhancing research"

Research Interests:

• Molecular function prediction, design (proteins, DNA)

• Computational genomics

• Evolutionary bioinformatics and computational biology

[WCMR] June 18, 2018, receives Thermo Fisher Scientific Award

[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners

[Waterloo Stories] January 26, 2018 "Scientists find new kind of botox"

Research Interests:

• Microbial diversity and function at contaminated sites (primarily municipal landfills)
• DNA, RNA, and protein (meta-omics) sequences
• Environment remediation
• Impacts of human activities on the environment

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Canada Research Chair in Environmental Microbiology [Canada Research Chair Profile]

[YouTube] October 23, 2015 "Piecing life together - microbial diversity and function through meta-omic analyses"

[Waterloo Stories] April 12, 2016 "New tree of life may hold clues to cleaning up pollution"

Research Interests:

• Clinical trial design
• Contact lens performance
• Drug delivery
• Ocular biomaterials
• Proteins at interfaces

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University Research Chair

Office of Research - Technology Transfer & Commercialization:

• Long-lasting Eye Drop Delivery Platform for Targeted Ocular Delivery Applications

Research Interests:

• Innate immunity of amphibians
• Regulation of innate immune cell development (macrophages, neutrophils) from progenitor cell populations
• Host-pathogen-environment interactions

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Research interests:

• Developing machine learning and statistical methods for genomics and proteomics data analysis using interpretable machine learning, reproducible (error-controlled) machine learning, and heterogeneous data integration
• Developing interpretation methods to find scientifically interesting and statistically confident hypotheses from complex biological data from single-cell genomics, mass spectrometry-based proteomics, and metagenomics

Research Interests:

• Protein structure, functions, evolution (yeast, mammalian cell lines, plant-bacterial)

• Bioinformatics, systematics and protein evolution

• Protein structure and interaction modeling
• Protein expression pattern analysis
• Molecular genetics

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Research Interests:

• Experimental biological physics
• Stochastic processes in physics and biology
• Pysiological constraints on bioproduct synthesis

Lab Equipment: Imagestream MkII with 488nm, 642nm and 785nm lasers; 60x magnification

[YouTube Lectures] Winter School on Quantitative Systems Biology 2015