Mike Beazely
519-888-4567 x21310
Location: 
PHR 4007

Research Interests:

  • Treatment of neurological disorders (Alzheimer’s, Parkinson’s, and mental health conditions including schizophrenia and depression)

  • Molecular pharmacology and pharmaceutical delivery

  • Intracellular signaling pathways in neurons, and the role of cytoskeletal dynamics in the trafficking of receptors in neurons

ResearchGate

LinkedIn

Google Scholar

Group(s): 
Application Areas→Aging, Mental Health, Neurodegenerative Diseases; Technology Areas→Disease Modelling, Imaging; Discipline Areas→Biochemistry, Biology, Cell Biology, Pharmacology, Physiology; Faculty→Science
Javad Behravan

Research Interests

  • Breast cancer, glioblastoma and acute lymphoblastic leukemia (ALL)
  • Vaccine development
  • Immunotherapy
  • Phage based nanomedicine

Google Scholar

Group(s): 
Application Areas→Cancer; Technology Areas→Drug Development, Therapeutics, Vaccines; Discipline Areas→Biochemistry, Biology, Bionanotechnology, Biotechnology, Cell Biology, Genetic Engineering, Immune Engineering, Nanotechnology, Pharmacology, Tissue Engineering; Faculty→Science
Andrea Edginton
519-888-4567 x21315
Location: 
PHR 5007

Research Interests:

  • Pharmacokinetics of drugs and environmental contaminants
  • Optimization of drug therapy
  • Physiologically-based Pharmacokinetic (PBPK) modeling and simulation (prediction of the absorption, distribution and elimination of a compound within an organism)
Group(s): 
Technology Areas→Therapeutics; Discipline Areas→Pharmacology; Faculty→Science
D. Edwards
519-888-4408
Location: 
PHR 6002

Research Interests:

  • Effect of food, beverages, herbal products and other drugs on drug metabolism and disposition
  • Investigation of the interaction between grapefruit juice and prescription medication
  • pharmacokinetics
  • drug metabolism

  • pharmacogenomics

  • drug interactions

  • bioavailability/bioequivalence

LinkedIn

Group(s): 
Application Areas→Disease Modelling, Environmental Biotechnology, Neurodegenerative Diseases, Personalized Medicine, Targeted Drug Delivery; Technology Areas→Biomarkers, Biomaterials, Disease Modelling, Drug Development; Discipline Areas→Biomedical Engineering, Biomedicine, Pharmacology; Faculty→Science
K.Grindrod
519-888-4567 x21358
Location: 
PHR 4014

Research Interests:

  • Mobile health technologies and social media in medication management

  • Clinical and post-marketing phases of medication use

  • Improve medication use and primary care via emerging technologies (mobile apps, social media)

  • Pharmacy remuneration models and chronic disease management services in the community pharmacy setting

  • Usability of mobile health applications and wearable activity trackers for older adults living with chronic disease.

LinkedIn

ResearchGate

​[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners

​[Waterloo Stories] November 16, 2016 "The opioid crisis: How pharmacists can help save lives"

Group(s): 
Application Areas→Disease Modelling, Healthcare Systems, Personalized Medicine, Wearable Devices; Technology Areas→Disease Modelling; Discipline Areas→Pharmacology; Faculty→Science
Emmanuel Ho
519-888-4567 x21372
Location: 
PHR 4002

Research interests:

  • Imaging, treatment, and prevention of diseases
  • Fabrication and characterization of innovative biomaterials for drug delivery systems (nanoparticles, medical devices, biodegradable films, hydrogels, etc.)
  • Vaccine development for protection against HIV and other diseases

Google Scholar

[Waterloo News] February 6, 2019 "Researchers find new treatment for Chlamydia"

[Waterloo News] April 16, 2018 "Developing new way to fight transmission of HIV"

Group(s): 
Application Areas→Cancer, Disease Modelling, Infectious Diseases, Inflammatory Diseases, Pathogen Detection, Personalized Medicine, Targeted Drug Delivery, Wound Care; Technology Areas→3D Printing/Additive Manufacturing, Biomaterials, Disease Modelling, Gene Therapy, Medical Devices, Microfabrication, Polymer, Surface Coating, Vaccines; Discipline Areas→Biochemistry, Biomedical Engineering, Bionanotechnology, Biotechnology, Cell Biology, Chemistry, Nanotechnology, Pharmacology, Polymer Chemistry; Faculty→Science
J. Honek
519-888-4567 x35817
Location: 
ESC 327

Research Interests:

  • Methionine chemistry and biochemestry (amino acid methionine and its roles in proteins, cellular pathways and its functions)

  • Bionanomaterials, bionanotechnology (for novel drug carriers, molecular foundations for nanodevices)

  • Medicinal chemistry

  • Enzymology
  • Bioorganic chemistry
  • Protein structure and function

ResearchGate

[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners

Group(s): 
Application Areas→Cancer, Environmental Biotechnology, Industrial Biotechnology, Infectious Diseases, Targeted Drug Delivery, Toxicology; Technology Areas→3D Printing/Additive Manufacturing, Biomarkers, Biomaterials, Computational Modeling, Drug Development, Imaging, Polymer, Therapeutics; Discipline Areas→Biochemistry, Bioinformatics, Bionanotechnology, Biophysics, Bioprocessing/Biochemical Engineering, Biotechnology, Cell Biology, Chemistry, Genetic Engineering, Nanotechnology, Pharmacology, Polymer Chemistry, Toxicology; Faculty→Science
L.Jones
519-888-4065
Location: 
OPT 228

Research Interests:

  • Clinical trial design
  • Contact lens performance
  • Drug delivery
  • Ocular biomaterials
  • Proteins at interfaces

LinkedIn

ResearchGate

Google Scholar

University Research Chair

Office of Research - Technology Transfer & Commercialization:

Group(s): 
Application Areas→Aging, Industrial Biotechnology, Optometry, Pathogen Detection, Personalized Medicine, Targeted Drug Delivery, Toxicology, Wearable Devices; Technology Areas→Biomarkers, Biomaterials, Diagnostics, Drug Development, Imaging, Medical Devices, Microbiome, Polymer, Sensors, Surface Coating, Therapeutics; Discipline Areas→Biochemistry, Biology, Biomedical Engineering, Biomedicine, Biophysics, Biotechnology, Cell Biology, Industrial Biotechnology, Nanotechnology, Pharmacology, Polymer Chemistry, Toxicology; Faculty→Science; University Research Chairs
Subha Kalyaanamoorthy photo
519-888-4567 x35804
Location: 
ESC 234

Research Interests:

  • Design/discovery of potential therapeutics to target various diseases
  • Understanding the structure and pharmacology of membrane proteins
  • Development of in silico methods/tools for sequence, structure and functional analysis
  • Inferring the structure-function evolution of proteins
  • Protein engineering for biotechnology and pharmaceutical applications

[American Chemical Society] January 23, 2012 "Exploring Inhibitor Release Pathways in Histone Deacetylases Using Random Acceleration Molecular Dynamics Simulations"

[Wiley Online Library] July 27, 2013 "Ligand release mechanisms and channels in histone deacetylases"

[Royal Society of Chemistry] December 19, 2013 "A steered molecular dynamics mediated hit discovery for histone deacetylases"

[Nature Methods] May 8, 2017 "ModelFinder: fast model selection for accurate phylogenetic estimates"

[Royal Society of Chemistry] October 24, 2017 "Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction"

Group(s): 
Application Areas→Cancer, Cardiovascular, Data Science, Industrial Biotechnology, Neurodegenerative Diseases, Stroke; Technology Areas→Biomaterials, Computational Modeling, Drug Development, Machine Learning/AI, Polymer, Therapeutics; Discipline Areas→Biochemistry, Bioinformatics, Biomedicine, Biophysics, Environmental Biotechnology, Industrial Biotechnology, Pharmacology, Synthetic Biology; Faculty→Science
Zoia Leonenko

Research Interests:

  • Biophysics of lipids and lipid-protein interactions

  • The role of structural changes and physical properties of lipid template in controlling biological processes and diseases

  • Biomedical nanotechnology (lipid films, molecular mechanism of Alzheimer's disease)

  • Drug development and delivery systems, antimicrobial peptides in lung disorders

  • Fluorescence and atomic force microscopy

  • Kelvin probe force microscopy and single molecule force spectroscopy

LinkedIn

ResearchGate

Google Scholar

[Global Impact] May 2018, studying Alzheimer's at a molecular level to find a cure

[YouTube Lecture] October 1, 2014 "Scanning probe microscopy in biomedical research"

Group(s): 
Application Areas→Aging, Diabetes, Disease Modelling, Environmental Biotechnology, Industrial Biotechnology, Infectious Diseases, Inflammatory Diseases, Mental Health, Neurodegenerative Diseases, Pathogen Detection, Personalized Medicine, Targeted Drug Delivery, Toxicology; Technology Areas→Biomaterials, Disease Modelling, Drug Development, Imaging, Medical Devices, Sensors, Surface Coating, Therapeutics, Vaccines; Discipline Areas→Biochemistry, Biology, Biomedical Engineering, Biomedicine, Bionanotechnology, Biophysics, Biotechnology, Cell Biology, Electrical and Computer Engineering, Environmental Biotechnology, Nanotechnology, Pharmacology, Physics, Polymer Chemistry, Toxicology; Faculty→Science
Kaylena Ehgoetz Martens
519-888-4567, ext. 37615
Location: 
BMH 1054
Group(s): 
Application Areas→Aging, Biomechanics, Data Science, Disease Modelling, Fall Prevention, Neurodegenerative Diseases, Optometry, Personalized Medicine, Rehabilitation, Virtual Reality, Wearable Devices; Technology Areas→Biomarkers, Diagnostics, Imaging, Machine Learning/AI, Sensors, Therapeutics; Discipline Areas→Bioinformatics, Biomechanical Engineering, Biomedical Engineering, Biomedicine, Biotechnology, Computer Science, Electrical and Computer Engineering, Industrial Biotechnology, Kinesiology, Mechanical and Mechatronics Engineering, Nanotechnology, Pharmacology, Physiology; Faculty→Applied Health Sciences
John Mielke
519-888-4567 x38843
Location: 
BMH 2107

Research interests: 

  • Neurobiological embedding of adversity
  • Biological characteristics that influence outcome from brain injury
  • Drug development, biomarkers
  • Stroke; biological characteristics that influence outcomes from brain injury

Google Scholar

Group(s): 
Application Areas→Stroke; Technology Areas→Biomarkers, Drug Development; Discipline Areas→Biochemistry, Biology, Biomedicine, Cell Biology, Pharmacology, Physiology, Public Health; Faculty→Applied Health Sciences
P. Nekkar
519-888-4567 x21317
Location: 
PHR 5002

Research Interests:

  • Drug discovery
  • Rational drug design and medicinal chemistry
  • Cancer therapy
  • Treatment of neurological disorders (Alzheimer's, Parkinson's)
  • Drug discovery/rational design
  • Synthesis and biological evaluation of novel organic molecules and peptides/peptidomimics as therapeutic agents

ResearchGate

Google Scholar

[Science News] October 22, 2018 "Nekkar lab determines that depression medications can help treat Alzheimer’s disease"

​[Pharmacy News] July 29, 2015 "Waterloo pharmacist examines drug therapies for Alzheimer’s disease"

Group(s): 
Application Areas→Aging, Cancer, Inflammatory Diseases, Neurodegenerative Diseases; Technology Areas→Biomarkers, Biomaterials, Computational Modeling, Diagnostics, Drug Development, Medical Devices, Therapeutics; Discipline Areas→Biochemistry, Biology, Biomedical Engineering, Biomedicine, Biophysics, Cell Biology, Chemistry, Pharmacology; Faculty→Science
Tejal Patel photo
519-888-4567 x21337
Location: 
PHR 7001
Group(s): 
Application Areas→Aging, Healthcare Systems; Technology Areas→Medical Devices, Therapeutics; Discipline Areas→Human Factors, Pharmacology, Physiology
D. Spafford
519-888-4567 x38185
Location: 
B1 172D

Research Interests:

  • Calcium channel analysis for target drug delivery for treatment of pain, arrhythmias, angina, and potential benefits in treatment of epilepsy and cancer.

  • Structure, function and pharmacology of calcium channels and sodium channels

  • Structure and function and analysis of NALCN cation channel  and anti-calcium channel toxins

  • The Spafford Neurobiology Research Laboratory studies voltage-gated calcium channels, molecular physiology, biophysics, cell biology, protein biochemistry, fluorescence microscopy and tissue cultures.

LinkedIn

ResearchGate

​Google Scholar

[Science News] April 25, 2014 "Waterloo discovers a key regulator in the pacemakers of our brain and heart"

Group(s): 
Application Areas→Biomechanics, Cardiovascular, Neurodegenerative Diseases, Stroke, Targeted Drug Delivery; Technology Areas→Biomarkers, Computational Modeling, Disease Modelling, Drug Development, Imaging; Discipline Areas→Biochemistry, Biology, Biomedicine, Biophysics, Biotechnology, Cell Biology, Pharmacology, Physiology; Faculty→Science
S.Taylor
519-888-4567 x33325
Location: 
C2 388

Research Interests:

  • Medicinal chemistry/enzymology (treatment of prostate and breast cancer, diabetes)

  • Nanomedicine; development of novel antibiotics

  • Bionanomaterials; synthetic polymers and methodologies

  • Peptide, charbohydrate, nucleoside and nucleotide chemistry

[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners

[Science News] February 4, 2015 "Chemists develop new method to improve the discovery of antibiotics"

Group(s): 
Application Areas→Cancer, Diabetes, Infectious Diseases, Targeted Drug Delivery, Wound Care; Technology Areas→Biomaterials, Drug Development, Polymer, Therapeutics; Discipline Areas→Biochemistry, Biomedicine, Bionanotechnology, Chemistry, Pharmacology, Polymer Chemistry, Synthetic Biology; Faculty→Science
Madjid Soltani
Group(s): 
Application Areas→Cancer, Cardiovascular, Data Science, Disease Modelling, Environmental Biotechnology, Industrial Biotechnology, Optometry, Personalized Medicine, Rehabilitation, Wearable Devices, Wound Care; Technology Areas→Computational Modeling, Diagnostics, Disease Modelling, Drug Development, Imaging, Machine Learning/AI, Medical Devices, Microfabrication, Microfluids; Discipline Areas→Bioinformatics, Biomechanical Engineering, Biomedical Engineering, Biomedicine, Bionanotechnology, Biophysics, Biosystem Engineering, Biotechnology, Computer Science, Electrical and Computer Engineering, Environmental Biotechnology, Kinesiology, Mechanical and Mechatronics Engineering, Nanotechnology, Pharmacology, Public Health, Regenerative Medicine, Tissue Engineering; Faculty→Engineering

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