Our People - Bioprocessing/Biochemical Engineering

Research Interests:

• Dynamics and control of MEMS
• Design of MEMS devices
• Micro-power generation
• Multi-body dynamics and control
• Biomechanics

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Research Interests:

• Pathogen detection, disinfection and sterilization using UV light

• Photochemistry, photocatalytic applications to water and air treatment

• Environmental engineering

• Biotechnology, biofiltration

• Metal nanoparticle synthesis and applications

• Process modelling and simulation

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Research Interests:

• Viral vector drug delivery

• Biological nano-particles (Virus-Like Particles or VLPs)

• Vaccines, gene therapy, gene expression, genetic diseases

• Baculovirus Bioprocessing

• Process dynamics of virus-based systems for the production of complex biologics such as viral vectors and vaccines

• Development of strategies using multiple viruses to obtain recombinant products in cell culture

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[YouTube Lecture] September 30, 2014 "Tools and strategies for complex biologics production in animal cells: applications to insect and mammalian cell culture"

[YouTube] January 26, 2011 "Research Profile: Marc Aucoin"

Research Interests:

• Characterization And Modelling Of The Behaviour Of Construction Materials
• Smart Pavement Materials And Structures
• Mechanistic Pavement Design Methods
• Optimization Of The Use Of Recycled Materials In Sustainable Infrastructure System
• Sustainable Development
• Life Cycle Analysis

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Research Interests:

• Research, in vitro toxicology, and biotechnology of animal cell cultures
• Roles of nutrition, hormones and polypeptide growth factors on the growth and differentiation of fish tissues and organs.

Research Interests:

• Chemical process control - Robust control, Nonlinear control, Model Predictive Control (MPC)

• Systems biology - modeling, control and optimization of biological processes, metabolic flux analysis, dynamic metabolic flux models, run-to-run (batch to batch) optimization of pharmaceutical process

• Monitoring/Fault Detection of chemical and biological/biotechnological processes - Multivariate statistical methods for monitoring and fault detection, Inferential (soft) sensors

Research Interests:

• Nano-Biomedical engineering, biochemistry, molecular cell biology

• Colloid and Surface Science (surface chemistry, absorption kinetics, thermodynamics)

• Polymer materials, CO2

• Energy storage and conversion, battery systems and alternative energy

• Drug and gene delivery, genomics

• Lipid bilayer and cell membrane actions

University Research Chair

Research Interests:

• Biochemical engineering

• Microbial biotechnology

• Synthetic and molecular biology

• Genetic, metabolic and protein engineering

• Biopharmaceuticals (to treat autoimmune diseases and prevent rejection of organ transplants)

• Biomanufacturing, bioprocessing technologies (biological strain construction, bioreaction cultivation, biofuels, bioproduct recovery and purification)

[Waterloo Stories] May 3, 2013 "Can bacteria help create a cheaper fuel for our cars?"

[UW Eng-e-news] August 14, 2013 "Engineering Life-enhancing research"

Research Interests:

• CO2 capture from large point sources
• Large scale optimization of energy systems
• Solid oxide fuel cell (SOFC)
• Syngas/Hydrogen production, Reaction Engineering

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Research Interests:

• Effects of toxic chemicals, including metals and oilsands process water, on aquatic organisms, principally fish.
• Biotic modifying factors of toxicity.
• Development of methods for environmental effects monitoring.
• Physiologically based pharmacokinetic modelling of contaminant levels in fish.

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[Waterloo Stories] March 21, 2013 "A river runs through it: Keeping an eye on the Alberta oil sands"

Research Interests:

• Methionine chemistry and biochemestry (amino acid methionine and its roles in proteins, cellular pathways and its functions)

• Bionanomaterials, bionanotechnology (for novel drug carriers, molecular foundations for nanodevices)

• Medicinal chemistry

• Enzymology
• Bioorganic chemistry
• Protein structure and function

ResearchGate

[Daily Bulletin] June 1, 2018, 11 CBB Members Named Outstanding Performance Award Winners

Research Interests:

• Micro and nano-analytical chemistry
• Micro and nano samples
• Micro-miniaturization (lab-on-a-chip)

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[YouTube] June 7, 2013 "Energy scavenging to power remote sensors"

Research Interests:

• Biochemical engineering
• Protein and biomimetic engineering
• Biosensor development
• Bioprocess monitoring and soft sensor development
• Protein thermodynamics stability and analysis
• Environmental bioremediation and green bioprocesses
• Biological water treatment and membrane-based processes
• Spectroscopic techniques combined with chemometric methods for process optimization and the development of on-line sensor technology

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ResearchGate

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Research Interests:

• Integrated microsystems for clinical and environmental monitoring

• Combining complementary metal-oxide-semiconductor (CMOS) integrated circuits with novel materials, structures, or devices to enable non-traditional life science and bio-diagnostic applications

• CMOS-integrated biochemical assays

• Semiconductor integrated circuits and sensors, design and test of 3D integrated circuits

• Micro/nano fabrication, lab-on-a-chip devices

• Electrochemical biosensors

• Electrophysiology

• DNA sequencing

• Image sensors

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​Google Scholar

Research Interests:

• Bioinformatics tools (protein structures, genome mapping, conducting homology searches)

• Protein structure prediction, and automated NMR protein structure determination

• Stem cell image recognition

• Deep learning, natural language processing and automated conversation, AI

Google Scholar

Canada Research Chair in Bioinformatics [Canada Research Chair Profile]

The Royal Society of Canada Fellow

[Waterloo Stories] April 5, 2013 "RSVP: Responding to a need"

[Waterloo Stories] July 6, 2012 "Solving life's big issues, one question at a time"

Research Interests:

• Static mixer and microreactor technology
• Polymer reaction engineering and polymer processing
• Waste minimization and green engineering

• Micro Process Systems Engineering - Design and Operation of Microfluidic reactors for efficient synthesis of biodiesel and complex copolymers.

• Mixed Integer Nonlinear Programming and Global Optimization Algorithms.

• Modeling and Optimal Control for Complex Biochemical Reaction Systems.

• Applied Statistics- Modeling, Design of Experiments, Parameter Estimation

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Research Interests:

• Proteins: energetics, kinetics, mechanisms, structure, dynamics, folding, function, evolution, engineering and design, thermodynamics, kinetics (ALS, Alzheimer's, Parkinson's, prions, cancer)

• High resolution nuclear magnetic resonance spectroscopy (fluorescence, CD, NMR, FTIR, DLS)

• Optical spectroscopies

• Bioinformatics and computational modelling

• Biocomputing and protein engineering

• Biophysical chemistry and biochemistry
• Bionanotechnology and biomaterials

​[Waterloo News] November 24, 2015 "New insights into protein structure could change the future of biomedicine"

[​Chemistry News] August 20, 2014 "Chemist Elizabeth Meiering takes on the ALS ice bucket challenge"

Research Interests:

• Polymer Science and Engineering
• Renewable polymers: Processing and Chemical Modifications
• Polymer blends, composites and nanocomposites

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Research Interests:

• Biopharmaceuticals (therapeutics, treatment of autoimmune diseases, prevent rejection of organ transplants)

• Industrial biomanufacturing and biotechnology (fermentation, food ingredients, enzymes, biofuels)

• Environmental management (bioremediation of carcinogenic environmental pollutants, filtration, chromatography)

The Royal Society of Canada Fellow

[YouTube Lecture] September 29, 2014 "Biofuels and Waste Treatment"

[YouTube Lecture] September 19, 2013 "Industrial Biotechnology: Current developments and trends"

[UW Eng-e-news] August 14, 2013 "Engineering Life-enhancing research"

[Waterloo Stories] May 3, 2013 "Can bacteria help create a cheaper fuel for our cars?"

[CBB researcher story] December 6, 2012 "Bringing Bioengineering and Biotechnology to its Fullest Potential"

Research Interests:

• Membrane filtration process (microfiltration; ultrafiltration; nanofiltration; reverse osmosis)

• Food proteins, processes, sustainability (concentration; separation; fractionation, water and waste minimization)

• Protein recovery and purification

• Enzyme reaction engineering

• Health food product development and processing

• Thermal food processes (baking; drying; ultra-high temperature; pasteurization; sterilization)

• Diffusion transport in biomaterials and polymeric films

Research Interests:

• Protein and DNA separation analysis towards disease diagnosis and drug discovery

• Biosensing and Devices (bacterial, proteins, fluorescence)

• Living cell analysis and water toxicity testing

• Lab-on-a-Chip technology (point-of-care biomedical diagnosis , chemical detection, protein separation and identification, environmental testing)

• Micro-scale fluid mechanics, droplet microfluidics and nanofluidics

• High Throughput Screening For Drug Screening
• Manufacturing Nanomaterials and Carbon Management

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ResearchGate

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Canada Research Chair in Lab-on-a-Chip Technology [Canada Research Chair Profile]

[Waterloo Stories] June 14, 2012 "Creating the tiny future of science"

Research Interests

• Early Cancer Detection
• Eliminating Positive Surgical Margins
• Non-contact Biopsies for Endoscopy 
• Functional Brain Imaging 
• Early Detection and Understanding the Age-related Vision Loss Problems. 

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Research Interests:

• Experimental biological physics
• Stochastic processes in physics and biology
• Pysiological constraints on bioproduct synthesis

Lab Equipment: Imagestream MkII with 488nm, 642nm and 785nm lasers; 60x magnification

[YouTube Lectures] Winter School on Quantitative Systems Biology 2015

Research Interests:

• Microalgae
• Microfluidics
• Biophotoreactors
• Biomass conversion
• Heterogeneous catalysis

Research Gate

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[Engineering News] March 9, 2018 "Finds manure can yield energy and ease global warming"

Research Interests:

• Enhanced drug delivery systems, gene therapy

• Associative polymers for environmentally friendly coatings

• Sustainable nanomaterials (cellulose nanocrystals)

• Atom Transfer Radical Polymerization (ATRP) and stimuli responsive polymeric systems

• Polymer-surfactant interactions

• Magnetic nanoparticles for novel separation processes

University Research Chair

Google Scholar

Research Interests:

• Biochemistry and molecular biology of programmed cell death

• Functional genomics of senescence (biological aging) and apoptosis

• Comparative aspects of senescence and stress including the role of hormones and the involvement of free radicals

• Applicable therapies for cancers, inflammatory diseases (arthritis and sepsis), and in the agricultural sector (enhance yield, develop tolerance to environmental stress and plant diseases, and increase the shelf-life of perishable produce)

The Royal Society of Canada Fellow

Research interests:

• Environmental biology, industrial biotechnology, and therapeutics
• Production of sustainable chemicals
• Novel bioprocesses for applications in bioresource engineering and biorefining
• Microalgae, metabolic engineering, and ionic liquid based separations in biological systems

Google Scholar

Research Interests:

• Bionanomaterials and “soft” interfaces

• Biomimetic adhesion, bio-integrated devices

• Nanoparticles synthesis, functionalization and dispersion, nanocomposites

• Polymers, interfacial phenomena and surface chemistry

• Advanced coating and adhesive bonding technology

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[Waterloo Stories] December 16, 2016 "New Gecko Gripper can be used in manufacturing and medicine"

[YouTube Video] June 11, 2015 "Zebra Mussel-inspired Electrically Conductive Polymer Nanofiber"

[Waterloo Stories] September 16, 2013 "Waterloo researcher is developing nano-glue for electronics"

Office of Research - Technology Transfer & Commercialization:

• Underwater "Superglue"