Our People - Stem Cell Engineering

M. Foldvari
519-888-4567 x21306
Location: 
PHR 3003

Research Interests:

  • Intelligent drug delivery system design (dermal, transdermal, transmucosal, ocular, and intranasal) for Dermatology, Ophthalmology, Cancer, Immunology (Glaucoma, neural degenerative disorders, HPV, LSIL/CIN I, cervical cancer, Scleroderma)

  • Non-invasive drug delivery technologies, biomolecular devices

  • Gene therapy, protein, and vaccine development

  • Nanomedicine, pharmaceutical development

  • Nanotoxicology (nanomaterials, bioimaging, biomarkers)

LinkedIn

ResearchGate

[Global Impact] [CBC] April 30, 2018 "Working with gene therapy to treat glaucoma"

[Waterloo Stories] July 5, 2012 "Revolutionary drug delivery"

Group(s): 
Application Areas→Infectious Diseases, Neurodegenerative Diseases, Optometry, Personalized Medicine, Targeted Drug Delivery; Technology Areas→Biomaterials, Drug Development, Gene Therapy, Imaging, Microfluids, Therapeutics, Vaccines; Discipline Areas→Biomedicine, Bionanotechnology, Biotechnology, Genetic Engineering, Nanotechnology, Regenerative Medicine, Stem Cell Engineering, Toxicology; Faculty→Science
M. Li
519-888-4659 or 519-888-4567, ext. 84659
Location: 
DC 3355

Research Interests:

  • Bioinformatics tools (protein structures, genome mapping, conducting homology searches)

  • Protein structure prediction, and automated NMR protein structure determination

  • Stem cell image recognition

  • Deep learning, natural language processing and automated conversation, AI

Google Scholar

Canada Research Chair in Bioinformatics [Canada Research Chair Profile]

The Royal Society of Canada Fellow

[Waterloo Stories] April 5, 2013 "RSVP: Responding to a need"

[Waterloo Stories] July 6, 2012 "Solving life's big issues, one question at a time"

Group(s): 
Application Areas→Disease Modelling; Technology Areas→Biomaterials, Cell Therapy, Gene Therapy, Imaging, Machine Learning/AI; Discipline Areas→Bioinformatics, Biology, Biomedical Engineering, Bioprocessing/Biochemical Engineering, Biotechnology, Chemistry, Computer Science, Stem Cell Engineering; Faculty→Mathematics; Canada Research Chairs; The Royal Society of Canada Fellows
Veronika Magdanz
519-888-4567 x41532
Location: 
E7 6432

Research Interests:

  • microrobots

  • sperm cells
  • magnetic actuation
  • remote control
  • wireless
  • soft robots
  • medical robots
  • bioprinting
  • 3D printing

We develop microrobots for medical applications. The goal is to develop more targeted, active, but less invasive strategies for drug or cell delivery with the help of wireless, autonomously moving microrobots. One strategy is to combine biological elements with artificial components in a biohybrid approach. The biological component (cells, molecules) can serve as power source, loading unit or structural unit.

One example is the "spermbot" - a sperm cell remotely controlled with magnetic fields: https://phys.org/news/2014-01-sperm-bots-desired-video.html
Another example is IRONSperm: a magnetically functionalized nonmotile sperm driven by magnetic fields:https://www.science.org/doi/10.1126/sciadv.aba5855

Inspired by the motion of sperm, we also develop small scale flexible magnetic robots for noninvasive surgery (coming soon). I am also interested in reproductive biology and research that elucidates reasons for infertility. We look into the mechanisms of sperm migration and some interesting phenomena, such as sperm bundling (publication online soon)

[Google Scholar]

Group(s): 
Application Areas→Cancer, Cardiovascular, Disease Modelling, Neurodegenerative Diseases, Personalized Medicine, Targeted Drug Delivery; Technology Areas→3D Printing/Additive Manufacturing, Biomaterials, Medical Devices, Microfabrication, Polymer, Robotics, Surface Coating; Discipline Areas→Biochemistry, Biology, Biomechanical Engineering, Biomedical Engineering, Biomedicine, Bionanotechnology, Biophysics, Biosystem Engineering, Biotechnology, Cell Biology, Chemistry, Nanotechnology, Polymer Chemistry, Regenerative Medicine, Robotics, Stem Cell Engineering, Tissue Engineering; Faculty→Engineering
Bruce Reed
519-888-4567 x38085
Location: 
B2 293A

Research Interests:

  • Molecular genetics

  • Cell and Developmental Biology

  • Stem Cell Biology & Cellular Differentiation
  • Programmed Cell Death
  • Live-Imaging Microscopy

Google Scholar

Group(s): 
Application Areas→Data Science; Technology Areas→Cell Therapy, Imaging; Discipline Areas→Biology, Cell Biology, Stem Cell Engineering; Faculty→Science
Evelyn Yim
519-888-4567 x33928
Location: 
E6 4014

Research Interests:

  • Stem cells, nanofabrication and advancement of biomaterials in healthcare technologies to repair, replace or regenerate damaged tissue and organ structures

  • Fabrication and application of nano-structure for biomedical applications in neural, vascular, and cornea tissue engineering

  • ​Biomaterial approach to study ex-vivo pluripotent stem cell expansion

  • Modulation of cell behavior with nanotopography

  • Topography-regulation of stem cells lineage commitment and differentiation

  • Differentiation of adult and pluripotent stem cells with nanotopography

Google Scholar

LinkedIn

Group(s): 
Application Areas→Cardiovascular, Disease Modelling, Neurodegenerative Diseases, Optometry, Personalized Medicine, Stroke, Targeted Drug Delivery; Technology Areas→Biomaterials, Cell Therapy, Disease Modelling, Medical Devices, Microfabrication, Polymer, Surface Coating, Therapeutics; Discipline Areas→Biomechanical Engineering, Biomedical Engineering, Biotechnology, Cell Biology, Nanotechnology, Regenerative Medicine, Stem Cell Engineering, Tissue Engineering; Faculty→Engineering

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