Contact Us:
Centre for Bioengineering and Biotechnology
University of Waterloo, East Campus 4, Room 2001
200 University Avenue West
Waterloo , Ontario, N2L 3G1 Canada
cbb.uwaterloo.ca
519-888-4567 Ext 32732
Research Interests:
Intelligent drug delivery system design (dermal, transdermal, transmucosal, ocular, and intranasal) for Dermatology, Ophthalmology, Cancer, Immunology (Glaucoma, neural degenerative disorders, HPV, LSIL/CIN I, cervical cancer, Scleroderma)
Non-invasive drug delivery technologies, biomolecular devices
Gene therapy, protein, and vaccine development
Nanomedicine, pharmaceutical development
Nanotoxicology (nanomaterials, bioimaging, biomarkers)
[Global Impact] [CBC] April 30, 2018 "Working with gene therapy to treat glaucoma"
[Waterloo Stories] July 5, 2012 "Revolutionary drug delivery"
Research Interests:
Bioinformatics tools (protein structures, genome mapping, conducting homology searches)
Protein structure prediction, and automated NMR protein structure determination
Stem cell image recognition
Canada Research Chair in Bioinformatics [Canada Research Chair Profile]
The Royal Society of Canada Fellow
[Waterloo Stories] April 5, 2013 "RSVP: Responding to a need"
[Waterloo Stories] July 6, 2012 "Solving life's big issues, one question at a time"
Research Interests:
microrobots
We develop microrobots for medical applications. The goal is to develop more targeted, active, but less invasive strategies for drug or cell delivery with the help of wireless, autonomously moving microrobots. One strategy is to combine biological elements with artificial components in a biohybrid approach. The biological component (cells, molecules) can serve as power source, loading unit or structural unit.
One example is the "spermbot" - a sperm cell remotely controlled with magnetic fields: https://phys.org/news/2014-01-sperm-bots-desired-video.html
Another example is IRONSperm: a magnetically functionalized nonmotile sperm driven by magnetic fields:https://www.science.org/doi/10.1126/sciadv.aba5855
Inspired by the motion of sperm, we also develop small scale flexible magnetic robots for noninvasive surgery (coming soon). I am also interested in reproductive biology and research that elucidates reasons for infertility. We look into the mechanisms of sperm migration and some interesting phenomena, such as sperm bundling (publication online soon)
[Google Scholar]
Research Interests:
Molecular genetics
Cell and Developmental Biology
Research Interests:
Stem cells, nanofabrication and advancement of biomaterials in healthcare technologies to repair, replace or regenerate damaged tissue and organ structures
Fabrication and application of nano-structure for biomedical applications in neural, vascular, and cornea tissue engineering
Biomaterial approach to study ex-vivo pluripotent stem cell expansion
Modulation of cell behavior with nanotopography
Topography-regulation of stem cells lineage commitment and differentiation
Differentiation of adult and pluripotent stem cells with nanotopography
Centre for Bioengineering and Biotechnology
University of Waterloo, East Campus 4, Room 2001
200 University Avenue West
Waterloo , Ontario, N2L 3G1 Canada
cbb.uwaterloo.ca
519-888-4567 Ext 32732
The University of Waterloo acknowledges that much of our work takes place on the traditional territory of the Neutral, Anishinaabeg and Haudenosaunee peoples. Our main campus is situated on the Haldimand Tract, the land granted to the Six Nations that includes six miles on each side of the Grand River. Our active work toward reconciliation takes place across our campuses through research, learning, teaching, and community building, and is co-ordinated within the Office of Indigenous Relations.