- Genomics, proteins, antibodies
- Molecular immunology and immunotoxicology in fish populations and the design for better vaccines for aquaculture
Canada Research Chair in Fish and Environmental Immunology [Canada Research Chair Profile]
[UW Science News] June 15, 2018, Waterloo Biologist mentors local teen, the 2018 International BioGENEius Challenge winner
[Waterloo Stories] January 22, 2018 "Vaccines not protecting farmed fish from disease"
[Waterloo Stories] February 13, 2014 "True love makes pacific salmon healthier"
[YouTube] October 9, 2013 "Science Scoop - For the love of fish!"
[Waterloo Stories] September 9, 2013 "Video conferencing connects Waterloo biologist to young students"
- Imaging, treatment, and prevention of diseases
- Fabrication and characterization of innovative biomaterials for drug delivery systems (nanoparticles, medical devices, biodegradable films, hydrogels, etc.)
- Vaccine development for protection against HIV and other diseases
[Waterloo News] February 6, 2019 "Researchers find new treatment for Chlamydia"
[Waterloo News] April 16, 2018 "Developing new way to fight transmission of HIV"
- GTP-dependent phosphoenolpyruvate carboxykinases
- IgA1 protease family of bacterial proteases
Biophysics of lipids and lipid-protein interactions
The role of structural changes and physical properties of lipid template in controlling biological processes and diseases
Biomedical nanotechnology (lipid films, molecular mechanism of Alzheimer's disease)
Drug development and delivery systems, antimicrobial peptides in lung disorders
Fluorescence and atomic force microscopy
Kelvin probe force microscopy and single molecule force spectroscopy
[Global Impact] May 2018, studying Alzheimer's at a molecular level to find a cure
[YouTube Lecture] October 1, 2014 "Scanning probe microscopy in biomedical research"
- Drug discovery
- Rational drug design and medicinal chemistry
- Cancer therapy
- Treatment of neurological disorders (Alzheimer's, Parkinson's)
- Drug discovery/rational design
- Synthesis and biological evaluation of novel organic molecules and peptides/peptidomimics as therapeutic agents
[Science News] October 22, 2018 "Nekkar lab determines that depression medications can help treat Alzheimer’s disease"
[Pharmacy News] July 29, 2015 "Waterloo pharmacist examines drug therapies for Alzheimer’s disease"
Biochemistry and molecular biology of programmed cell death
Functional genomics of senescence (biological aging) and apoptosis
Comparative aspects of senescence and stress including the role of hormones and the involvement of free radicals
Applicable therapies for cancers, inflammatory diseases (arthritis and sepsis), and in the agricultural sector (enhance yield, develop tolerance to environmental stress and plant diseases, and increase the shelf-life of perishable produce)
The Royal Society of Canada Fellow
Big data, computer vision and image processing, health engineering, terahertz imaging, fuzzy image processing
Machine intelligence, opposition-based learning, pattern recognition
Medical imaging and analysis (CT, MR, and ultrasound imaging)
[News Medical Life Sciences] June 28, 2018 Artificial Intelligence and Machine Learning in Medical Imaging
[GRH News] May 31, 2018, "GRH partners with UW researchers and Huron Digital Pathology to create a “digital revolution” in pathology with medical search engine"
[Daily Bulletin] May 29, 2018, $3.7M in funding for AI and medical imaging project
[Exchange Magazine] May 22, 2018, Speaks about “Faster, Better, More Reliable than Deep Features: A Projection-Based, Pathologist-Centric Approach to Identification of Histopathology Images” at the Pathology Informatics Summit in Pittsburgh, PA.
[YouTube Lecture] January 21, 2015 "BIG Data, Medical Imaging and Machine Intelligence"
[YouTube Lecture] October 1, 2014 "Medical Imaging: Pixels, Consensus and Learning"
[Waterloo Stories] January 9, 2013 "Making it harder for cancer to hide"
Biomaterials and mechanics of biomaterials and tissues
Bone quality and fragility, collagen
Engineering of bone mimetic materials for skeletal reconstruction (3D printing)