Our People - Inflammatory Diseases

Research Interests:

• Genomics, proteins, antibodies
• Molecular immunology and immunotoxicology in fish populations and the design for better vaccines for aquaculture

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Canada Research Chair in Fish and Environmental Immunology [Canada Research Chair Profile]

[UW Science News] June 15, 2018, Waterloo Biologist mentors local teen, the 2018 International BioGENEius Challenge winner

[Waterloo Stories] January 22, 2018 "Vaccines not protecting farmed fish from disease"

[Waterloo Stories] February 13, 2014 "True love makes pacific salmon healthier"

[YouTube] October 9, 2013 "Science Scoop - For the love of fish!"

[Waterloo Stories] September 9, 2013 "Video conferencing connects Waterloo biologist to young students"

Research interests:

• Imaging, treatment, and prevention of diseases
• Fabrication and characterization of innovative biomaterials for drug delivery systems (nanoparticles, medical devices, biodegradable films, hydrogels, etc.)
• Vaccine development for protection against HIV and other diseases

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[Waterloo News] February 6, 2019 "Researchers find new treatment for Chlamydia"

[Waterloo News] April 16, 2018 "Developing new way to fight transmission of HIV"

Research interests: 

• GTP-dependent phosphoenolpyruvate carboxykinases
• IgA1 protease family of bacterial proteases

Research Interests:

• Biophysics of lipids and lipid-protein interactions

• The role of structural changes and physical properties of lipid template in controlling biological processes and diseases

• Biomedical nanotechnology (lipid films, molecular mechanism of Alzheimer's disease)

• Drug development and delivery systems, antimicrobial peptides in lung disorders

• Fluorescence and atomic force microscopy

• Kelvin probe force microscopy and single molecule force spectroscopy

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[Global Impact] May 2018, studying Alzheimer's at a molecular level to find a cure

[YouTube Lecture] October 1, 2014 "Scanning probe microscopy in biomedical research"

Research Interests:

• Drug discovery
• Rational drug design and medicinal chemistry
• Cancer therapy
• Treatment of neurological disorders (Alzheimer's, Parkinson's)
• Drug discovery/rational design
• Synthesis and biological evaluation of novel organic molecules and peptides/peptidomimics as therapeutic agents

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[Science News] October 22, 2018 "Nekkar lab determines that depression medications can help treat Alzheimer’s disease"

​[Pharmacy News] July 29, 2015 "Waterloo pharmacist examines drug therapies for Alzheimer’s disease"

Research Interests:

• Biochemistry and molecular biology of programmed cell death

• Functional genomics of senescence (biological aging) and apoptosis

• Comparative aspects of senescence and stress including the role of hormones and the involvement of free radicals

• Applicable therapies for cancers, inflammatory diseases (arthritis and sepsis), and in the agricultural sector (enhance yield, develop tolerance to environmental stress and plant diseases, and increase the shelf-life of perishable produce)

The Royal Society of Canada Fellow

Research Interests:

• Big data, computer vision and image processing, health engineering, terahertz imaging, fuzzy image processing

• Machine intelligence, opposition-based learning, pattern recognition

• Medical imaging and analysis (CT, MR, and ultrasound imaging)

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[News Medical Life Sciences] June 28, 2018 Artificial Intelligence and Machine Learning in Medical Imaging

[GRH News] May 31, 2018, "GRH partners with UW researchers and Huron Digital Pathology to create a “digital revolution” in pathology with medical search engine"

[Daily Bulletin] May 29, 2018, $3.7M in funding for AI and medical imaging project

[Exchange Magazine] May 22, 2018, Speaks about “Faster, Better, More Reliable than Deep Features: A Projection-Based, Pathologist-Centric Approach to Identification of Histopathology Images” at the Pathology Informatics Summit  in Pittsburgh, PA.

[Waterloo New] [Engineering News] May 22, 2018, Electrical and Computer Engineering,  $12 million awarded to Waterloo researchers

[YouTube Lecture] January 21, 2015 "BIG Data, Medical Imaging and Machine Intelligence"

[YouTube Lecture] October 1, 2014 "Medical Imaging: Pixels, Consensus and Learning"

[Waterloo Stories] January 9, 2013 "Making it harder for cancer to hide"

Research Interests:

• Biomaterials and mechanics of biomaterials and tissues

• Bone quality and fragility, collagen

• Engineering of bone mimetic materials for skeletal reconstruction (3D printing)

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