Our People - Inflammatory Diseases

Brian Dixon
519-888-4567 x32665
B2 247A

Research Interests:

  • Genomics, proteins, antibodies
  • Molecular immunology and immunotoxicology in fish populations and the design for better vaccines for aquaculture



Google Scholar

Canada Research Chair in Fish and Environmental Immunology [Canada Research Chair Profile]

[UW Science News] June 15, 2018, Waterloo Biologist mentors local teen, the 2018 International BioGENEius Challenge winner

[Waterloo Stories] January 22, 2018 "Vaccines not protecting farmed fish from disease"

[Waterloo Stories] February 13, 2014 "True love makes pacific salmon healthier"

[YouTube] October 9, 2013 "Science Scoop - For the love of fish!"

[Waterloo Stories] September 9, 2013 "Video conferencing connects Waterloo biologist to young students"

Application Areas→Environmental Biotechnology, Infectious Diseases, Inflammatory Diseases, Pathogen Detection; Technology Areas→Biomarkers, Diagnostics, Vaccines; Discipline Areas→Biochemistry, Biology, Biotechnology, Cell Biology, Immune Engineering, Physiology; Faculty→Science; Canada Research Chairs
Emmanuel Ho
519-888-4567 x21372
PHR 4002

Research interests:

  • Imaging, treatment, and prevention of diseases
  • Fabrication and characterization of innovative biomaterials for drug delivery systems (nanoparticles, medical devices, biodegradable films, hydrogels, etc.)
  • Vaccine development for protection against HIV and other diseases

Google Scholar

[Waterloo News] February 6, 2019 "Researchers find new treatment for Chlamydia"

[Waterloo News] April 16, 2018 "Developing new way to fight transmission of HIV"

Application Areas→Cancer, Disease Modelling, Infectious Diseases, Inflammatory Diseases, Pathogen Detection, Personalized Medicine, Targeted Drug Delivery, Wound Care; Technology Areas→3D Printing/Additive Manufacturing, Biomaterials, Disease Modelling, Gene Therapy, Medical Devices, Microfabrication, Polymer, Surface Coating, Vaccines; Discipline Areas→Biochemistry, Biomedical Engineering, Bionanotechnology, Biotechnology, Cell Biology, Chemistry, Nanotechnology, Pharmacology, Polymer Chemistry; Faculty→Science
T. Holyoak
519-888-4567 x31559
ESC 249

Research interests: 

  • GTP-dependent phosphoenolpyruvate carboxykinases
  • IgA1 protease family of bacterial proteases
Application Areas→Cancer, Diabetes, Infectious Diseases, Inflammatory Diseases; Technology Areas→Computational Modeling, Drug Development, Imaging; Discipline Areas→Biochemistry, Bioinformatics, Biology, Biophysics; Faculty→Science
Zoia Leonenko

Research Interests:

  • Biophysics of lipids and lipid-protein interactions

  • The role of structural changes and physical properties of lipid template in controlling biological processes and diseases

  • Biomedical nanotechnology (lipid films, molecular mechanism of Alzheimer's disease)

  • Drug development and delivery systems, antimicrobial peptides in lung disorders

  • Fluorescence and atomic force microscopy

  • Kelvin probe force microscopy and single molecule force spectroscopy



Google Scholar

[Global Impact] May 2018, studying Alzheimer's at a molecular level to find a cure

[YouTube Lecture] October 1, 2014 "Scanning probe microscopy in biomedical research"

Application Areas→Aging, Diabetes, Disease Modelling, Environmental Biotechnology, Industrial Biotechnology, Infectious Diseases, Inflammatory Diseases, Mental Health, Neurodegenerative Diseases, Pathogen Detection, Personalized Medicine, Targeted Drug Delivery, Toxicology; Technology Areas→Biomaterials, Disease Modelling, Drug Development, Imaging, Medical Devices, Sensors, Surface Coating, Therapeutics, Vaccines; Discipline Areas→Biochemistry, Biology, Biomedical Engineering, Biomedicine, Bionanotechnology, Biophysics, Biotechnology, Cell Biology, Electrical and Computer Engineering, Environmental Biotechnology, Nanotechnology, Pharmacology, Physics, Polymer Chemistry, Toxicology; Faculty→Science
P. Nekkar
519-888-4567 x21317
PHR 5002

Research Interests:

  • Drug discovery
  • Rational drug design and medicinal chemistry
  • Cancer therapy
  • Treatment of neurological disorders (Alzheimer's, Parkinson's)
  • Drug discovery/rational design
  • Synthesis and biological evaluation of novel organic molecules and peptides/peptidomimics as therapeutic agents


Google Scholar

[Science News] October 22, 2018 "Nekkar lab determines that depression medications can help treat Alzheimer’s disease"

​[Pharmacy News] July 29, 2015 "Waterloo pharmacist examines drug therapies for Alzheimer’s disease"

Application Areas→Aging, Cancer, Inflammatory Diseases, Neurodegenerative Diseases; Technology Areas→Biomarkers, Biomaterials, Computational Modeling, Diagnostics, Drug Development, Medical Devices, Therapeutics; Discipline Areas→Biochemistry, Biology, Biomedical Engineering, Biomedicine, Biophysics, Cell Biology, Chemistry, Pharmacology; Faculty→Science
John Thompson
EC5 3131

Research Interests:

  • Biochemistry and molecular biology of programmed cell death

  • Functional genomics of senescence (biological aging) and apoptosis

  • Comparative aspects of senescence and stress including the role of hormones and the involvement of free radicals

  • Applicable therapies for cancers, inflammatory diseases (arthritis and sepsis), and in the agricultural sector (enhance yield, develop tolerance to environmental stress and plant diseases, and increase the shelf-life of perishable produce)

The Royal Society of Canada Fellow

Application Areas→Aging, Cancer, Environmental Biotechnology, Inflammatory Diseases, Mental Health; Technology Areas→Biomarkers, Disease Modelling, Therapeutics; Discipline Areas→Biochemistry, Biology, Biomedical Engineering, Bioprocessing/Biochemical Engineering, Chemistry, Genome Engineering, Nanotechnology; Faculty→Science; The Royal Society of Canada Fellows
Hamid T
519-888-4567 x46751
E7 6314

Research Interests:

  • Big data, computer vision and image processing, health engineering, terahertz imaging, fuzzy image processing

  • Machine intelligence, opposition-based learning, pattern recognition

  • Medical imaging and analysis (CT, MR, and ultrasound imaging)



[News Medical Life Sciences] June 28, 2018 Artificial Intelligence and Machine Learning in Medical Imaging

[GRH News] May 31, 2018, "GRH partners with UW researchers and Huron Digital Pathology to create a “digital revolution” in pathology with medical search engine"

[Daily Bulletin] May 29, 2018, $3.7M in funding for AI and medical imaging project

[Exchange Magazine] May 22, 2018, Speaks about “Faster, Better, More Reliable than Deep Features: A Projection-Based, Pathologist-Centric Approach to Identification of Histopathology Images” at the Pathology Informatics Summit  in Pittsburgh, PA.

[Waterloo New] [Engineering News] May 22, 2018, Electrical and Computer Engineering,  $12 million awarded to Waterloo researchers

[YouTube Lecture] January 21, 2015 "BIG Data, Medical Imaging and Machine Intelligence"

[YouTube Lecture] October 1, 2014 "Medical Imaging: Pixels, Consensus and Learning"

[Waterloo Stories] January 9, 2013 "Making it harder for cancer to hide"

Application Areas→Cancer, Data Science, Healthcare Systems, Inflammatory Diseases, Personalized Medicine; Technology Areas→Computational Modeling, Diagnostics, Imaging, Machine Learning/AI; Discipline Areas→Biomedical Engineering, Computer Science; Faculty→Engineering
Thomas Willett
519-888-4567 x48405
E7 6438

Research Interests:

  • Biomaterials and mechanics of biomaterials and tissues

  • Bone quality and fragility, collagen

  • Engineering of bone mimetic materials for skeletal reconstruction (3D printing)

Google Scholar

Application Areas→Aging, Biomechanics, Cancer, Diabetes, Inflammatory Diseases, Muscle, Joint and Bone Diseases, Wound Care; Technology Areas→3D Printing/Additive Manufacturing, Biomarkers, Biomaterials, Computational Modeling, Imaging, Medical Devices; Discipline Areas→Biochemistry, Biology, Biomechanical Engineering, Biomedical Engineering, Kinesiology, Regenerative Medicine, Tissue Engineering; Faculty→Engineering

Contacts by group