Centre for Bioengineering and Biotechnology
University of Waterloo, East Campus 4, Room 2001
200 University Avenue West
Waterloo , Ontario, N2L 3G1 Canada
519-888-4567 Ext 32732
Machining of Tissue-Engineered Bone Implants
Precision motion control (high speed machine tools, robots, and electronic/semiconductor manufacturing equipment)
Modeling and identification
Optimal trajectory planning
[Engineering News] October 19, 2016 "Researchers join advanced manufacturing network"
We develop microrobots for medical applications. The goal is to develop more targeted, active, but less invasive strategies for drug or cell delivery with the help of wireless, autonomously moving microrobots. One strategy is to combine biological elements with artificial components in a biohybrid approach. The biological component (cells, molecules) can serve as power source, loading unit or structural unit.
One example is the "spermbot" - a sperm cell remotely controlled with magnetic fields: https://phys.org/news/2014-01-sperm-bots-desired-video.html
Another example is IRONSperm: a magnetically functionalized nonmotile sperm driven by magnetic fields:https://www.science.org/doi/10.1126/sciadv.aba5855
Inspired by the motion of sperm, we also develop small scale flexible magnetic robots for noninvasive surgery (coming soon). I am also interested in reproductive biology and research that elucidates reasons for infertility. We look into the mechanisms of sperm migration and some interesting phenomena, such as sperm bundling (publication online soon)
Nanomaterials, nanodevices, biosensors for applications in food processing, bioreactors and biotechnology, natural gas purification, fuel cell, and water purification
Nano-Bio Hybrids for Tissue Engineering and Medicine for drug delivery, tissue engineering and regenerative medicine
Bio-molecule assisted nanomaterial self-assembly
Health and environmental effects of engineered nanomaterials
Tissue engineering and biodegradable implants for regenerative medicine (3D printing)
Bio-additive and microscale-additive manufacturing (opto-mechanical sensors, smart structures, developed through additive manufacturing)
Novel multi-scale additive manufacturing technologies for biomedical, oil/gas and manufacturing sectors
Laser-based fabrication techniques with particular focus on direct write processes in micro- and macro-scale
Modeling, sensing and real-time control of laser-based manufacturing techniques
University Research Chair
Canada Research Chair in Multi-Scale Additive Manufacturing [Canada Research Chair Profile]
[Office of Research News] May 8,2018 "Waterloo researchers named Canada Research Chairs"
[YouTube Lecture] May 6, 2014 "Additive manufacturing"
Office of Research - Technology Transfer & Commercialization:
Biomaterials and mechanics of biomaterials and tissues
Bone quality and fragility, collagen
Engineering of bone mimetic materials for skeletal reconstruction (3D printing)
Stem cells, nanofabrication and advancement of biomaterials in healthcare technologies to repair, replace or regenerate damaged tissue and organ structures
Fabrication and application of nano-structure for biomedical applications in neural, vascular, and cornea tissue engineering
Biomaterial approach to study ex-vivo pluripotent stem cell expansion
Modulation of cell behavior with nanotopography
Topography-regulation of stem cells lineage commitment and differentiation
Differentiation of adult and pluripotent stem cells with nanotopography
Biopharmaceuticals (therapeutics, treatment of autoimmune diseases, prevent rejection of organ transplants)
Industrial biomanufacturing and biotechnology (fermentation, food ingredients, enzymes, biofuels)
Environmental management (bioremediation of carcinogenic environmental pollutants, filtration, chromatography)
The Royal Society of Canada Fellow
[YouTube Lecture] September 29, 2014 "Biofuels and Waste Treatment"
[YouTube Lecture] September 19, 2013 "Industrial Biotechnology: Current developments and trends"
[UW Eng-e-news] August 14, 2013 "Engineering Life-enhancing research"
[Waterloo Stories] May 3, 2013 "Can bacteria help create a cheaper fuel for our cars?"
[CBB researcher story] December 6, 2012 "Bringing Bioengineering and Biotechnology to its Fullest Potential"
The University of Waterloo acknowledges that much of our work takes place on the traditional territory of the Neutral, Anishinaabeg and Haudenosaunee peoples. Our main campus is situated on the Haldimand Tract, the land granted to the Six Nations that includes six miles on each side of the Grand River. Our active work toward reconciliation takes place across our campuses through research, learning, teaching, and community building, and is co-ordinated within the Office of Indigenous Relations.