Guest Speaker: Dr. Kostadinka Bizheva
(Associate Professor, Department of Physics and Astronomy, University of Waterloo)
Title of Presentation: "Non-invasive optical imaging of the structure and function of biological tissue with Optical Coherence Tomography"
Refreshments will be available!
Abstract: Abnormal development of biological tissue, as well as the early stages of many diseases exhibit structural changes occurring on cellular level, alterations in the local blood flow, and complex changes in the cellular biochemistry. Both biological science and current medical practice call for development of novel, minimally invasive methods capable of detecting these changes. The novel technologies can be used to provide understanding of the origins and the time course of development of different pathologies, as well as to diagnose diseases at early stages when treatment is most effective and irreversible damage can be avoided or postponed. This presentation will introduce a relatively novel non-invasive optical imaging technique, ultrahigh resolution optical coherence tomography (UHROCT), that permits in-vivo cross-sectional visualization of tissue morphology in superficial depths of 1-2 mm in non-transparent biological tissue with micrometer scale resolution. The principles of image formation in UHROCT and the possibility of extracting functional information (spectroscopic and flow measurements) about the imaged object will be reviewed. Current applications of UHROCT in ophthalmology, dermatology, neuroscience and neurosurgery will be discussed.
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