University of Waterloo
Engineering 6 (E6)
Phone: 519-888-4567
Staff and Faculty Directory
Contact the Department of Chemical Engineering
Thursday, October 17, 2013 — 3:30 PM EDT
Mousa Jafari, PhD
Post-Doctoral Fellow
University of Waterloo
RNA interference is a post-transcriptional gene silencing process whereby short interfering RNAs (siRNAs) induce the sequence-specific degradation of complementary messenger RNA. Despite their promising therapeutic capabilities, siRNA-based strategies suffer from enzymatic degradation and poor cellular uptake. Several carrier-based approaches have been employed to enhance the stability and efficiency of siRNA delivery.