ABSTRACT: In this work we present results on the use of Gamma-Polyglutamic Acid (PGA) biopolymer to produce nanoparticles and encapsulate the anti-cancer drug Doxorubicin (DOX). Microbially produced PGA is used alone and in combination with Chitosan (CS) to form DOX-loaded nanoparticles at different conditions. The main mechanism of nanoparticle formation is the ionic complexation between PGA, DOX and CS.
Friday, September 18, 2015 — 10:00 to 10:00 AM EDT
Friday, September 18, 2015 — 1:00 PM EDT