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DTSTART;TZID=America/Toronto:20250526T153000
SEQUENCE:0
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URL:https://uwaterloo.ca/chemical-engineering/events/designing-hydrogel-bio
 materials-therapeutic
LOCATION:E6 - Engineering 6 200 University Ave West E6 Room 4022 Waterloo O
 N N2L 3G1 Canada
SUMMARY:Designing Hydrogel Biomaterials for Therapeutic Revascularization
CLASS:PUBLIC
DESCRIPTION:Abstract :\n\nHeart failure remains one of the leading causes o
 f death worldwide\,\ndriven by persistent coronary artery occlusion that r
 educes blood\nsupply to the myocardium\, leading to cardiomyocyte death an
 d fibrotic\nremodeling. Effective revascularization of the injured myocard
 ium is\nessential to restore tissue viability and preserve cardiac functio
 n.\nIn this talk\, I will present our strategies for engineering hydrogel\
 nplatforms to actively promote revascularization. We developed a\ncomputat
 ionally designed affinity-based delivery system to precisely\nregulate the
  presentation of proangiogenic growth factors\, and\noptimized matrix prop
 erties to support the transplantation and\nfunctional integration of CD34
 ⁺ vascular progenitor cells. Together\,\nthese approaches aim to create 
 a regenerative microenvironment capable\nof driving robust and functional 
 vascularization.\n\nBiography:\n\nDr. Yuan Yao is an Assistant Professor i
 n the Department of Mechanical\nEngineering and Division of Cardiology at 
 University of British\nColumbia. She graduated from University of Waterloo
 \, supervised by Dr.\nEvelyn Yim\, and completed her postdoctoral training
  with Dr. Molly\nShoichet in the Department of Chemical Engineering at Uni
 versity of\nToronto. Her lab is located at the Center for Heart Lung Innov
 ation at\nthe St Paul’s Hospital in Vancouver.\n\nHer research focuses o
 n engineered biomaterials and biofabrication\napproaches for cardiovascula
 r repair and regeneration.
DTSTAMP:20260428T062749Z
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