Jean Duhamel

Professor & Director, Institute for Polymer Research

Contact InformationJean Duhamel

Phone: 519-888-4567 x35916
Location: C2 169


Biography Summary

Jean Duhamel is the Director of the Institute for Polymer Research at the University of Waterloo. He is well recognized for his expertise at applying fluorescence techniques to characterize synthetic or biological macromolecules and their supramolecular assemblies at the nanoscale in solution and in the solid state. DNA, peptides, polypeptides, dendrimers, or polymeric surfactants are examples of the types of macromolecules which are being currently studied in this laboratory.

Research Interests

  • Characterization of macromolecules by fluorescence
  • Colloidal particles
  • Chain folding using fluorescence
  • Smart Materials
  • Biomaterials and Polymers
  • Biochemistry and Biophysic
  • Bionanotechnolgy and Biosensors
  • Soft Matter
  • Devices and Analytical Methods
  • Smart and Functional Materials


  • 1989, Doctorate, Chemical Engineering, Institut National Polytechnique de Lorraine
  • 1987, Master of Science, Chemical Engineering, Institut National Polytechnique de Lorraine
  • 1987, Bachelor of Science (BSc), Chemical Engineering, cole Nationale Suprieure des Industries Chimiques

Selected/Recent Publications

  • Membrane Binding and Oligomer Formation by the Calcium-Dependent Lipopeptide Antibiotic A54145: A Quantitative Study with Pyrene Excimer Fluorescence
  • Long Range Polymer Chain Dynamics Studied by Fluorescence Quenching
  • Probing Side Chain Dynamics of Branched Macromolecules by Pyrene Excimer Fluorescence
  • A Pyrenyl Derivative with a Four Atom-Linker that Can Probe the Local Polarity of Pyrene-Labeled Macromolecules
  • Pyrene Excimer Fluorescence as a Direct and Easy Experimental Means to Characterize the Length Scale and Dynamics of Polypeptide Foldons. Casier, R.; Duhamel*, J. Macromolecules 2018, 51, 3450-3457.
  • Little H, Wang J, Duhamel J, Li X, Nagula M, Maurizot V, Huc I. Simplification in the Acquisition and Analysis of Fluorescence Decays Acquired with Polarized Emission for Time-Resolved Fluorescence Anisotropy Measurements. Analytical Chemistry. 2019.
  • Application of Pyrene Fluorescence to the Characterization of Hydrophobically Modified Starch Nanoparticles. Kim, D.; Amos, R.; Gauthier*, M. Duhamel*, J. Langmuir 2018, 34, 8611-8621.
  • Zhang Q, Kim D, Li L, Patel S, Duhamel J. Surfactant Structure-Dependent Interactions with Modified Starch Nanoparticles Probed by Fluorescence Spectroscopy. Langmuir. 2019 Feb 5;35(9):3432-44.
  • Hydrophobic and Elastic Forces Experienced by a Series of Pyrene End-Labeled Poly(ethylene oxide)s Interacting with Sodium Dodecyl Sulfate Micelles. Raimbault, J.; Casier, R.; Little, H.; Duhamel*, J. Macromolecules 2018, 51, 5933-5943.
  • Temperature-Controlled Interactions Between Poly(N-isopropylacrylamide) Mesoglobules Probed by Fluorescence. Fowler, M.; Duhamel*, J.; Qiu, X.-P.; Korchagina, E.; Winnik*, F. M. Macromolecules 2018, 51, 1946-1956.
  • Long Range Polymer Chain Dynamics of Highly Flexible Polysiloxane in Solution Probed by Pyrene Excimer Fluorescence. Thoma, J. L.; Duhamel*, J.; Bertocchi, M. J.; Weiss*, R. G. Polymers 2018, 10, 345/1-345/15.
  • Quantifying the Level of Intermacromolecular Interactions by Using Pyrene Excimer Formation

Graduate Studies