Chemistry Seminar Series: Robert BateyExport this event to calendar

Thursday, January 16, 2020 — 2:30 PM EST

Natural Product Inspired Synthetic Methods Development: Targetting Macrocycles and Alkaloids

Rob BateyRobert Batey ​​​​​​
Department of Chemistry
University of Toronto

Thursday, January 16, 2019
2:30 p.m.
C2-361 (Reading Room)

Abstract

Biologically active natural products including alkaloids, terpenoids, macrocyclic peptides and depsipeptides serve as an inspiration for many synthetic chemists. Their often complex and diverse structures can pose many interesting synthetic challenges. They can also act as potential lead structures for the development of pharmaceuticals or biological probe molecules, including anticancer, antibiotic, antiviral, antifungal, anti-inflammatory and CNS activities. Recent progress toward macrocyclization strategies for depsipeptide and peptide formation, as well as alkaloids will be described. Example targets include the ADEPs (e.g., A54556A), the syringolins, nagelamide J, and the agrobactins.

 

Stick figure diagrams of chemical reactions described in abstract.

Location 
C2 - Chemistry 2
Room 361
200 University Avenue West

Waterloo, ON N2L 3G1
Canada

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