UW Biomedical Seminar:
Professor Brian Tighe, Aston Biomaterials Unit, Aston Univeristy, UK Monday April 8th, 2:30 pm in DC-1304
All are welcome! Refreshments will be available.
If you'd like to meet with the speaker during his visit, please contact his host, Lyndon Jones.
Funding for this seminar series is provided by the Centre for Bioengineering and Biotechnology, as well as the Deans of Math and Science.
Title: Hydration and lubrication - Two important challenges for biomaterials development
Abstract: Biomaterials science is producing increasingly sophisticated and successful approaches to bodily repair and regeneration with synthetic materials, much of which stems from the pioneering work of Otto Wichterle. Two generic areas that present challenges to this success are bodily hydration and lubrication processes.
The ability to maintain and control hydration is important in many body sites - for example: dermal (skin and wounds), ocular (cornea and conjunctiva) and orthopaedic (connective tissue and intervertebral entities involved in maintaining hydration control in these very different tissues. Similarly, bodily lubrication mechanisms have many commonalities in the very diverse areas in which they operate
Although the fluids involved have different properties, the underlying compositions and behaviours show many similarities. Examples of this can be found in lung surfactant, synovial fluids and tears. The application of biomimetic principles to the development of both synthetic analogues of these fluids and clinically useful tissue substitutes, identifies and commonalities that underpin their function and enable a surprising degree of rationalisation in the process of involving biomaterials for various body sites.
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