Troy Day, Queens University, presents: "Insights into drug resistance evolution from simple mathematical models".
The evolution of resistance to drugs used for combating infectious diseases has become one of the most serious public health problems in modern medicine.
In this talk I will present some theoretical results that explore this problem from several different perspectives, with the goal of better mitigating the emergence and spread of resistance. I will show how simple mathematical models of the drug supply system, of the population-level epidemiology, and of the within-host dynamics of pathogen replication, can contribute to this goal. I will conclude by illustrating how these theoretical results suggest a new approach for preventing the evolution of resistance.
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