Recent Progress in Alzheimer’s Disease Research, Part 3: Diagnosis and Treatment

TitleRecent Progress in Alzheimer’s Disease Research, Part 3: Diagnosis and Treatment
Publication TypeJournal Article
Year of Publication2017
AuthorsHane, F., M. Robinson, B. Y. Lee, O. Bai, Z. Leonenko, and M. Albert
JournalJournal of Alzheimer's Disease
Volume57
Issue3
Pagination645-665
Date Published04/2017
KeywordsAlzheimer’s disease, biomarkers, diagnosis, mild cognitive impairment, MRI, PET, treatment
Abstract

The field of Alzheimer’s disease (AD) research has grown exponentially over the past few decades, especially since the isolation and identification of amyloid-β from postmortemexamination of the brains of AD patients. Recently, the Journal of Alzheimers Disease (JAD)put forth approximately 300 research reports which were deemed to be the most influential research reports in the field of AD since 2010. JAD readers were asked to vote on these most influential reports. In this 3-part review, we review the results of the 300 most influential AD research reports to provide JAD readers with a readily accessible, yet comprehensive review of the state of contemporary research. Notably, this multi-part review identifies the “hottest” fields of AD research providing guidance for both senior investigators as well as investigators new to the field on what is the most pressing fields within AD research. Part 1 of this review covers pathogenesis, both on a molecular and macro scale. Part 2 review genetics and epidemiology, and part 3 covers diagnosis and treatment. This part of the review, diagnosis and treatment, reviews the latest diagnostic criteria, biomarkers, imaging, and treatments in AD.

DOI10.3233/JAD-160907
Refereed DesignationRefereed
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