Murray Alzheimer Research and Education Program (MAREP)

Alzheimer's disease and related dementias are a world-wide phenomenon that ignores social class and national boundaries. As age is the greatest risk factor for the development of Alzheimer's disease, more and more individuals will be diagnosed with Alzheimer's disease and related dementias as the population ages.

At the present time there is no known cause or cure for Alzheimer's disease. As the search for an effective treatment continues, it is important that people who have Alzheimer's disease or a related dementia receive the best care possible and are provided with support and opportunities to live meaningful lives.

To implement effective approaches for care of people living with Alzheimer's disease and related dementias, contemporary research findings need to be brought to the attention of all partners in care including people with dementia, family members and friends, health care professionals, and so forth. The converse is true as well in that effective approaches to care need to be brought to the attention of researchers.

The Murray Alzheimer Research and Education Program (MAREP) is an innovative program that adopts a partnership approach and integrates research and educational activities in an effort to improve dementia care practices in Canada and around the world. Although MAREP's research projects are funded by research grants, all of its knowledge translation activities are funded through donations and charitable gifts from individuals and groups: find out how you can support our programs.

More information is available for people living with dementia, care partners, and anyone else affected by dementia in our Innovations Newsletter, published three times per year, the Dementia Weekly News Service, our blog, and the educational tools and training and workshops we offer. 

MAREP Murray Alzheimer Research and Education Program wordmark.

  1. July 16, 2018Multi-Testing Cognition Leads to Obscured Results

    In the preliminary stages of Alzheimer’s disease, conducting cognitive tests is vital to early diagnosis. The University of California San Diego School of Medicine conducted research on middle-aged men and found a “practice effect” when testing for cognition. Six years after initial testing, researchers retested the 995 men, as well as a cohort of 170 men who had not done the testing before. Differences in the two groups were used to differentiate the practice effect.

  2. July 16, 2018Drug Trial Success in Combating Alzheimer's Disease

    Drug development for dementia has been bleak for years, with a failure rate of 99.6%. After years of failed amyloid targeted approaches to drug development, the outlook was bleak. However, there is new hope after the Biogen drug company found statistically significant results for slowing the progression of Alzheimer’s disease. The drug, BAN2401, is a late-stage antibody that targets beta-amyloid proteins and was found to reduce progression at 18 months. After an initial failed result at 12 months, the company was thrilled to find positive results after 18 months.

  3. July 16, 2018Brain Lesions Associated with High Blood Pressure

    Research out of Rush University Medical Center in Chicago has found a link between blood pressure and lesions in the brain. After following 1288 older adults until death, the researchers looked at their brain composition and compared it to the average blood pressure of their participants. Those who had higher average systolic blood pressure were at an increased risk of developing brain lesions. There was also a dose response:  the higher the blood pressure, the higher the chance of lesions.

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  1. July 25, 2017Canada's National Dementia StrategyMary Beth Wighton Quote

    Last month, Bill C-233, an Act respecting a national strategy for Alzheimer’s disease and other dementias, sponsored by the Honourable Rob Nicholson and Rob Oliphant, was passed. Canada will be the 30th country out of 194 members of the World Health Organization to implement a national dementia plan.

  2. June 6, 2017To the Nurse Who May Care for Me TodayBlog quote

    Hi I am your assignment for today.

    I know I am just one of many but I ask you to please take the time to know me. You see I once was also a nurse. That really doesn't matter as I am a human being. I come with an education and feeling. I am also a wife a mother, a grandmother and more. Please take the time to read my chart as you can gain much knowledge about me before you ever meet me. In it you will find my medical history, this may give you a glimpse of what to expect from me. It will tell you what is being treated now. Know full well that, that may not be my only problem.  

  3. May 2, 2017Ontario Dementia Advisory Group e-newsletter, April 2017

    A Letter from the Chair

    APRIL 2017

    Hello, ODAG Members, Friends, and Supporters.

    The last two months have been very interesting for people living with dementia. It is a time of policy changes, budget allocations and the broadening of the Council of Canadians with Disabilities to formally include people living with dementia.

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