Murray Alzheimer Research and Education Program (MAREP)

Alzheimer's disease and related dementias are a world-wide phenomenon that ignores social class and national boundaries. As age is the greatest risk factor for the development of Alzheimer's disease, more and more individuals will be diagnosed with Alzheimer's disease and related dementias as the population ages.

At the present time there is no known cause or cure for Alzheimer's disease. As the search for an effective treatment continues, it is important that people who have Alzheimer's disease or a related dementia receive the best care possible and are provided with support and opportunities to live meaningful lives.

To implement effective approaches for care of people living with Alzheimer's disease and related dementias, contemporary research findings need to be brought to the attention of all partners in care including people with dementia, family members and friends, health care professionals, and so forth. The converse is true as well in that effective approaches to care need to be brought to the attention of researchers.

The Murray Alzheimer Research and Education Program (MAREP) is an innovative program that adopts a partnership approach and integrates research and educational activities in an effort to improve dementia care practices in Canada and around the world. Although MAREP's research projects are funded by research grants, all of its knowledge translation activities are funded through donations and charitable gifts from individuals and groups: find out how you can support our programs.

More information is available for people living with dementia, care partners, and anyone else affected by dementia in our Innovations Newsletter, published three times per year, the Dementia Weekly News Service, our blog, and the educational tools and training and workshops we offer. 

MAREP Murray Alzheimer Research and Education Program wordmark.

  1. May 22, 2018Surprising Result Finding Exercise May Make Dementia Symptoms Worse

    Exercise has long been shown to keep people healthy and often advised to promote mental health. However, in certain circumstances, this may not be correct and exercise may actually be harmful. Researchers from Oxford University sought to find if an exercise program would be beneficial to people with mild dementia. 494 people living with dementia were placed into two groups, those who received normal care and those who also participated in an exercise program twice a week and prescribed a home workout once a week.

  2. May 22, 2018RNA the Key to Memory?

    Researchers from UCLA have successfully been able to transfer memories from one snail to another using ribonucleic acid (RNA) injections. The snails were subjected to minor shocks to their tails, enhancing their defensive withdrawal reflex. When the researchers simply tapped their tails, the shocked snails exhibited a sensitisation reaction and contracted their tails for 50 seconds, whereas control snails would only contract for 1 second. RNA was extracted from 7 shocked snails and injected into normal snails. These snails then behaved as if they had been shocked themselves.

  3. May 22, 2018Mutation in Mice Reduces the Formation of Amyloid-Beta Plaques

    Researchers at the RIKEN Center for Brain Science have found a mutation in mice that has the potential to protect against Alzheimer’s disease. They found that this mutation can reduce the accumulation of amyloid-beta peptides. These amyloid-beta plaques are a hallmark sign of Alzheimer’s disease, created from the leftover part of the amyloid precursor protein (APP). They successfully recreated the APP gene mutation in mouse models for the purpose of the study. Previous research has shown that the deletion of the APP gene may reduce amyloid-beta plaques.

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  1. July 25, 2017Canada's National Dementia StrategyMary Beth Wighton Quote

    Last month, Bill C-233, an Act respecting a national strategy for Alzheimer’s disease and other dementias, sponsored by the Honourable Rob Nicholson and Rob Oliphant, was passed. Canada will be the 30th country out of 194 members of the World Health Organization to implement a national dementia plan.

  2. June 6, 2017To the Nurse Who May Care for Me TodayBlog quote

    Hi I am your assignment for today.

    I know I am just one of many but I ask you to please take the time to know me. You see I once was also a nurse. That really doesn't matter as I am a human being. I come with an education and feeling. I am also a wife a mother, a grandmother and more. Please take the time to read my chart as you can gain much knowledge about me before you ever meet me. In it you will find my medical history, this may give you a glimpse of what to expect from me. It will tell you what is being treated now. Know full well that, that may not be my only problem.  

  3. May 2, 2017Ontario Dementia Advisory Group e-newsletter, April 2017

    A Letter from the Chair

    APRIL 2017

    Hello, ODAG Members, Friends, and Supporters.

    The last two months have been very interesting for people living with dementia. It is a time of policy changes, budget allocations and the broadening of the Council of Canadians with Disabilities to formally include people living with dementia.

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