Alzheimer’s patients have been known to experience behavioural changes such as depression, apathy, irritability, and appetite loss, but researchers have not recognized how early these symptoms can appear, nor have they concretely established these symptoms as predictors or consequences of the disease.
A study conducted at the University of Southampton reveals that an increase in immune cells can actually drive the development of Alzheimer’s disease. Originally, the theory was that Alzheimer’s disease disturbs the immune response of the brain, but an experimental model shows evidence otherwise.
A new study discovered that blocking a receptor in the brain that regulates immune cells could prevent some changes to memory and behaviour observed in Alzheimer’s disease. This study adds to evidence that inflammation in the brain plays a role in the development of Alzheimer’s disease
The Dementia Discovery Fund, established last year with support from the U.K. government and several of the world’s largest pharmaceutical companies, aims to create at least one breakthrough dementia treatment by 2025. The fund has made its first investment of $29.5 million to San Francisco-based Alector LLC.