Brain antioxident levels indicate progression of Alzheimer’s disease

Monday, October 29, 2018

Glutathione is an antioxidant produced by the human body that protects the brain from stress, by preventing cell damage that can be caused by free radicals. Research has shown that glutathione is greatly depleted in patients with Alzheimer’s disease. In a recent study, an international team of scientists used a non-invasive imaging technique, known as Magnetic Resonance Spectroscopy (MRS), to detect two forms of glutathione (closed and extended) in the brain. When the closed form of glutathione is depleted in the hippocampus region of older adults, it leads to mild cognitive impairment, known to be present in the early stages of Alzheimer’s. The researchers suggest that routine MRS screening of the hippocampus for low levels of glutathione could allow early detection and perhaps intervention to slow the advance of the disease by providing glutathione supplements.

SOURCE: Journal of Alzheimer’s Disease, September 1, 2018
https://doi.org/10.3233/JAD-180648

DATE Retrieved: October 25, 2018

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