Mouse Study Uncovers Proteins That May Contribute to the Development of Alzheimer’s

Monday, November 6, 2017

Before now, scientists have always believed that Alzheimer’s disease was onset by proteins exclusively developed in the brain tissue. However, recent research from the University of British Columbia suggests that proteins created anywhere in the body can lead to the advancement of neurodegenerative diseases. The protein in question is the amyloid- β protein and has become the focus of Dr.Weihong Song and her team. Dr.Weihong Song is a Canada Research Chair in Alzheimer's disease and a UBC psychiatry professor. The protein does not have a known function, but it is normally produced everywhere in the body. They believe it is involved in the development of Alzheimer’s due to the larger amounts of the protein produced by the neurons in the brain of persons living with dementia. To test the validity of their statements, the scientists surgically conjoined mice, ones who did not normally develop Alzheimer’s and ones that were modified to produce amyloid- β in high amounts. They found out that, once the mice shared a bloodstream, the ones who did not normally develop Alzheimer’s ended up developing protein plaques and Alzheimer's disease-like pathologies within a year of being conjoined. 

SOURCE: CBC News October 31st, 2017

AUTHOR(S): Roshini Nair

DATE RETRIEVED: November 2nd 2017



 

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