Having a stroke increases the risk of developing dementia. Previous studies indicate that the use of statins (medication prescribed to lower cholesterol in the blood) is linked to lower risk of dementia, but the effect had not been investigated in stroke patients. Researchers in Taiwan used the National Health Insurance Research Database to look at records for 14,807 stroke patients, including both statin users and nonusers, to determine whether statin use was positively or negatively associated with the risk of dementia. Statin users tended to be young women diagnosed with hypertension, diabetes, or hyperlipidemia and ischemic heart disease. A total of 1,895 people developed dementia during the follow-up period (median, 7.5 years). The rate was lower among statin users than among nonusers. The authors conclude that stroke patients who use statins are 17% less likely to develop dementia. High potency, solubility and long-term cumulative use of statins were associated with a greater reduction of dementia risk. Results were consistent across gender and age groups.
SOURCE: Journal of Stroke and Cerebrovascular Diseases, November 2018
DATE Retrieved: October 25, 2018