Comparison of meibomian gland dropout using two infrared imaging devices

TitleComparison of meibomian gland dropout using two infrared imaging devices
Publication TypeJournal Article
Year of Publication2019
AuthorsWong, S., S. Srinivasan, P. J. Murphy, and L. Jones
JournalContact Lens and Anterior Eye
Keywordsadult, Article, clinical article, controlled study, Dry eye, eyelid erythema, female, human, Image analysis, image quality, Infrared imaging, Keratograph, Lipiview, lower eyelid, male, Meibography, meibomian gland, Meibomian gland dysfunction, pilot study, priority journal, prospective study, telangiectasia
Abstract{Purpose: To measure the degree of meibomian gland (MG) dropout in the lower eyelid determined by analysis of images obtained from the LipiView II (LVII) and the Keratograph 5M (K5M). Methods: The inferior eyelid of each participant was imaged in a random order using both devices. All images were subjectively assessed by a single-masked investigator to determine the extent of MG loss using the Arita 4-point meiboscore grading scale. The images were also semi-objectively analyzed with ImageJ to calculate the percentage of MG dropout, by tracing around the non-glandular area and the total exposed area of the lower lid. Results: Twenty participants (mean age 37 years, range 23–60, 60% female) completed the study. A significant difference in meiboscore (mean ± SD) was obtained between the LVII and the K5M (1.43 ± 0.78 vs. 1.90 ± 0.81