IMI – Myopia control reports overview and introduction

TitleIMI – Myopia control reports overview and introduction
Publication TypeJournal Article
Year of Publication2019
AuthorsWolffsohn, J. S., D. I. Flitcroft, K. L. Gifford, M. Jong, L. Jones, C. C. W. Klaver, N. S. Logan, K. Naidoo, S. Resnikoff, P. Sankaridurg, E. L. Smith, III, D. Troilo, and C. F. Wildsoet
JournalInvestigative Ophthalmology and Visual Science
Volume60
PaginationM1-M19
Keywords4 aminobutyric acid receptor, Article, behavior change, binocular convergence, binocular vision, biodiversity, biometry, circadian rhythm, Clinical guidelines, cycloplegic agent, Definition, disease exacerbation, education, environmental impact, epidemic, eye axis length, gene expression, genetics, glucagon, health care personnel, health center, incidence, insulin, intervention study, Interventions, Molecular biology, myopia, Myopia control, Myopic progression, neuropeptide, nitric oxide, Ophthalmology, optometry, posttranscriptional gene silencing, practice guideline, Prevalence, priority journal, protein expression, publication, refraction error, research, scientific literature
AbstractWith the growing prevalence of myopia, already at epidemic levels in some countries, there is an urgent need for new management approaches. However, with the increasing number of research publications on the topic of myopia control, there is also a clear necessity for agreement and guidance on key issues, including on how myopia should be defined and how interventions, validated by well-conducted clinical trials, should be appropriately and ethically applied. The International Myopia Institute (IMI) reports the critical review and synthesis of the research evidence to date, from animal models, genetics, clinical studies, and randomized controlled trials, by more than 85 multidisciplinary experts in the field, as the basis for the recommendations contained therein. As background to the need for myopia control, the risk factors for myopia onset and progression are reviewed. The seven generated reports are summarized: (1) Defining and Classifying Myopia, (2) Experimental Models of Emmetropization and Myopia, (3) Myopia Genetics, (4) Interventions for Myopia Onset and Progression, (5) Clinical Myopia Control Trials and Instrumentation, (6) Industry Guidelines and Ethical Considerations for Myopia Control, and (7) Clinical Myopia Management Guidelines. © 2019 The Authors.
DOI10.1167/iovs.18-25980