Prevalence of dry eye disease in Ontario, Canada: A population-based survey

TitlePrevalence of dry eye disease in Ontario, Canada: A population-based survey
Publication TypeJournal Article
Year of Publication2019
AuthorsCaffery, B., S. Srinivasan, C. Reaume, A. Fischer, D. Cappadocia, C. Siffel, and C. Chan
JournalOcular Surface
KeywordsDED, Dry eye disease, Epidemiology, Ocular surface disease, Population survey, Prevalence

Purpose: Population-based cross-sectional survey in Ontario to estimate the 2016 prevalence of dry eye disease (DED) and associated risk factors among adults in Canada. Methods: We emailed the 5-Item Dry Eye Questionnaire (DEQ-5) to 124,469 Ontario adults (age ≥18 years) in the IQVIA E360 database, March–April 2017. Inclusion criteria were: ≥2 visits to an Ontario based clinic, ≥1 visits in the 1 year before the study; database record with email. DED was defined as a DEQ-5 score of >6/22. The crude prevalence by age/sex of the Ontario sample was adjusted to the 2016 Canadian population (mean age 41.0 years, 51% female). Significance of DED risk factors (age, sex, selected diseases/medical conditions and medications) was evaluated by logistic regression analysis. Results: Of the 5163 (4.1%) patients who completed the survey (59.5% female, median age, 46 years; 40.4% male, 56 years), 1135 respondents reported DED. Prevalence increased with age (p 6 million Canadian adults may have DED, and that older people and females are more likely to be affected. © 2019 The Authors