The relief of dry eye signs and symptoms using a combination of lubricants, lid hygiene and ocular nutraceuticals

TitleThe relief of dry eye signs and symptoms using a combination of lubricants, lid hygiene and ocular nutraceuticals
Publication TypeJournal Article
Year of Publication2017
AuthorsNgo, W., S. Srinivasan, D. Houtman, and L. Jones
JournalJournal of Optometry
Keywordsadult, aged, analysis of variance, artificial tear, Conjunctiva, Cornea, dietary supplement, Dietary Supplements, Dry eye, Dry Eye Syndromes, eye drops, female, human, Humans, hygiene, lacrimal fluid, Lubricant Eye Drops, male, meibomian gland, Meibomian Glands, metabolism, middle aged, Nutraceutical, Nutrition, Ophthalmic Solutions, pathology, pathophysiology, Prospective Studies, prospective study, questionnaire, SteriLid, Surveys and Questionnaires, Tears, TheraTears, young adult

Purpose To determine the combined effect of TheraTears® Lubricant Eye Drops, TheraTears® SteriLid Eyelid Cleanser, and TheraTears® Nutrition on dry eye signs and symptoms. Methods This prospective study enrolled 28 dry eye participants. Participants were instructed to use the Lubricant Eye Drops at least 2–4× a day, SteriLid 1–2× a day, and Nutrition 3 gel caps once a day. Participants were followed up at baseline, 1 month and 3 months. Outcome variables were the Ocular Surface Disease Index (OSDI), Symptom Assessment iN Dry Eye (SANDE) questionnaire, non-invasive tear break-up time (NIBUT), osmolarity, number of meibomian glands blocked (#MG blocked), meibum quality, eyelid margin features, Schirmer's test, tear film lipid layer thickness (LLT), meniscus height, corneal and conjunctival staining. Results Twenty participants (mean age = 43, from 23 to 66, 17F, 3M) completed the study. Participants reported having used, on average, the Lubricant Eye Drop 2.4×/day, the SteriLid 1.1×/day, and the Nutrition 3 gel caps 1×/day. There was a significant change over time (p < 0.05) for OSDI (−21.2 points), SANDE (−32.4 points), NIBUT (+0.43 s), eyelid margin features (−1.1 grade), meibum quality (−1.0 grade), and #MG blocked (−4.0 glands). Conclusion By using a combination of TheraTears® Lubricant Eye Drop, SteriLid, and Nutrition, patients experience significant relief in both dry eye symptoms and signs. © 2016 Spanish General Council of Optometry