Soothing the burn: Repairing sun-damaged DNA with enzymesExport this event to calendar

Thursday, October 18, 2012 — 4:00 PM to 5:00 PM EDT

Dongping Zhong
Ohio State University

Abstract

Ultraviolet irradiation causes DNA damages and leads to genome mutation and potential skin cancer. However, such damage can be restored completely by photolyase enzymes in nature with blue light. Using femtosecond spectroscopy and molecular biology, we report here the real-time studies of complete repair processes at the most fundamental level and thus reveal the repair photocycle and elucidate the molecular mechanism.

Location 
PHY - Physics
150
200 University Avenue West

Waterloo, ON N2L 3G1
Canada

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