University of Waterloo
200 University Avenue West
Waterloo, Ontario, Canada N2L 3G1
Phone: (519) 888-4567 ext 32215
Fax: (519) 746-8115
Ohio State University
Ultraviolet irradiation causes DNA damages and leads to genome mutation and potential skin cancer. However, such damage can be restored completely by photolyase enzymes in nature with blue light. Using femtosecond spectroscopy and molecular biology, we report here the real-time studies of complete repair processes at the most fundamental level and thus reveal the repair photocycle and elucidate the molecular mechanism.
The University of Waterloo acknowledges that much of our work takes place on the traditional territory of the Neutral, Anishinaabeg and Haudenosaunee peoples. Our main campus is situated on the Haldimand Tract, the land granted to the Six Nations that includes six miles on each side of the Grand River. Our active work toward reconciliation takes place across our campuses through research, learning, teaching, and community building, and is centralized within our Indigenous Initiatives Office.