University of Waterloo
200 University Avenue West
Waterloo, Ontario, Canada N2L 3G1
Phone: (519) 888-4567 ext 32215
Fax: (519) 746-8115
Wayne State University - School of Medicine
To demonstrate the importance of understanding brain development.
To overview approaches in assessing structural, biochemical and functional changes during development.
Provide evidence of altered neuropil development and dysfunctional networks in pediatric ADHD.
ADHD is the most prevalent childhood disorder that seriously impacts public health. Regarding the etiology ADHD, there is considerable evidence of a developmental basis with a view of an early life insult impacting the developmental course of key cognitive and behavioral domains. However, the understanding on how altered brain development contributes to ADHD from the morphological, biochemical and functional perspective remains unclear. The purpose of the presentation is to provide evidence supporting a developmental dysmaturation of key neural systems in ADHD assessed using different Magnetic Resonance Imaging (MRI) methods. A focus on developmental changes of these different perspectives will enhance our ability to track illness progression, predict illness outcome, and as a consequence enhance the efficacy of early intervention.