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Author Title Type [ Year(Desc)]
2020
Prieto-García, L. , Vicente-Vicente, L. , Blanco-Gozalo, V. , Hidalgo-Thomas, O. , García-Macías, M. C. , Kurtz, A. , Layton, A. T. , et al. (2020). Pathophysiological mechanisms underlying a rat model of triple whammy acute kidney injury. Laboratory Investigation, 1–10. Nature Publishing Group.
Hu, R. , McDonough, A. A. , & Layton, A. T. . (2020). Sex differences in solute transport along the nephrons: effects of Na+ transport inhibition. American Journal of Physiology-Renal Physiology, 319(3), F487-F505. Retrieved from https://journals.physiology.org/doi/abs/10.1152/ajprenal.00240.2020
Sadria, M. , & Layton, A. T. . (2020). Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers During the COVID-19 Pandemic: A Modeling Analysis. PLOS Computational Biology, 16(10), e1008235. Retrieved from https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1008235
Sadria, M. , & Layton, A. . (2020). Ageing signalling pathways: Quantifying the effects of protein interactions. The FASEB Journal, 34, 1–1. The Federation of American Societies for Experimental Biology.
Edwards, A. , Palm, F. , & Layton, A. T. . (2020). A model of mitochondrial O2 consumption and ATP generation in rat proximal tubule cells. American Journal of Physiology-Renal Physiology, 318, F248–F259. American Physiological Society Bethesda, MD.
Ahmed, S. , & Layton, A. T. . (2020). Sex-specific computational models for blood pressure regulation in the rat. American Journal of Physiology-Renal Physiology, 318, F888–F900. American Physiological Society Bethesda, MD.
2021
Sadria, M. , & Layton, A. T. . (2021). Aging affects circadian clock and metabolism and modulates timing of medication. Iscience, 24, 102245. Elsevier.
Hu, R. , & Layton, A. . (2021). A computational model of kidney function in a patient with diabetes. International Journal of Molecular Sciences, 22, 5819. Multidisciplinary Digital Publishing Institute.
Docherty, N. G. , Delles, C. , D’Haese, P. , Layton, A. T. , Martínez-Salgado, C. , Vervaet, B. A. , & López-Hernández, F. J. . (2021). Haemodynamic Frailty-A Risk Factor for Acute Kidney Injury in the Elderly. Ageing Research Reviews, 101408. Elsevier.
Layton, A. T. . (2021). His and her mathematical models of physiological systems. Mathematical Biosciences, 108642. Elsevier.
Sadria, M. , Seo, D. , & Layton, A. T. . (2021). The Mixed Blessing of AMPK Signaling in Cancer Treatments. Available at SSRN 3889705.
Sadria, M. , & Layton, A. T. . (2021). Modeling Within-host SARS-CoV-2 Infection Dynamics and Potential Treatments. Viruses, 13, 1141. Multidisciplinary Digital Publishing Institute.
Swapnasrita, S. , Carlier, A. , & Layton, A. . (2021). Sex-Specific Computational Models of Kidney Function in Human Patients with Diabetes. bioRxiv. Cold Spring Harbor Laboratory.
Patterson, S. E. , & Layton, A. T. . (2021). Computing viscous flow along a 2D open channel using the immersed interface method. Engineering Reports, 3, e12334.
Casanova, A. G. , Fuentes-Calvo, I. , Hernández-Sánchez, M. T. , Quintero, M. , Toral, P. , Caballero, M. T. , Martínez-Salgado, C. , et al. (2021). The furosemide stress test and computational modeling identify renal damage sites associated with predisposition to acute kidney injury in rats. Translational Research, 231, 76–91. Mosby.
Ahmed, S. , Sullivan, J. C. , & Layton, A. T. . (2021). Impact of sex and pathophysiology on optimal drug choice in hypertensive rats: quantitative insights for precision medicine. Iscience, 24, 102341. Elsevier.
Sadria, M. , & Layton, A. T. . (2021). Interactions among mTORC, AMPK and SIRT: a computational model for cell energy balance and metabolism. Cell Communication and Signaling, 19, 1–17. BioMed Central.
Abo, S. M. C. , & Layton, A. T. . (2021). Modeling the circadian regulation of the immune system: Sexually dimorphic effects of shift work. PLoS computational biology, 17, e1008514. Public Library of Science.
Sadria, M. , & Layton, A. T. . (2021). Modeling the Effect of Ageing on the Circadian Clock and Metabolism: Implications on Timing of Medication. Available at SSRN 3720771.
Hu, R. , McDonough, A. A. , & Layton, A. T. . (2021). Sex differences in solute and water handling in the human kidney: Modeling and functional implications. iScience, 102667. Elsevier.

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