<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Srirangan, K.</style></author><author><style face="normal" font="default" size="100%">Bruder, M.</style></author><author><style face="normal" font="default" size="100%">Akawi, L.</style></author><author><style face="normal" font="default" size="100%">Miscevic, D.</style></author><author><style face="normal" font="default" size="100%">Kilpatrick, S.</style></author><author><style face="normal" font="default" size="100%">Moo-Young, M.</style></author><author><style face="normal" font="default" size="100%">Chou, C. P.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Recent advances in engineering propionyl-CoA metabolism for microbial production of value-added chemicals and biofuels</style></title><secondary-title><style face="normal" font="default" size="100%">Critical Reviews in Biotechnology</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2017</style></year></dates><number><style face="normal" font="default" size="100%">6</style></number><volume><style face="normal" font="default" size="100%">37</style></volume><pages><style face="normal" font="default" size="100%">701-722</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Diminishing fossil fuel reserves and mounting environmental concerns associated with petrochemical manufacturing practices have generated significant interests in developing whole-cell biocatalytic systems for the production of value-added chemicals and biofuels. Although acetylCoA is a common natural biogenic precursor for the biosynthesis of numerous metabolites, propionyl-CoA is unpopular and non-native to most organisms. Nevertheless, with its C3-acyl moiety as a discrete building block, propionyl-CoA can serve as another key biogenic precursor to several biological products of industrial importance. As a result, engineering propionyl-CoA metabolism, particularly in genetically tractable hosts with the use of inexpensive feedstocks, has paved an avenue for novel biomanufacturing. Herein, we present a systematic review on manipulation of propionyl-CoA metabolism as well as relevant genetic and metabolic engineering strategies for microbial production of value-added chemicals and biofuels, including odd-chain alcohols and organic acids, bio(co) polymers and polyketides. [GRAPHICS] .</style></abstract><notes><style face="normal" font="default" size="100%">Srirangan, Kajan Bruder, Mark Akawi, Lamees Miscevic, Dragan Kilpatrick, Shane Moo-Young, Murray Chou, C. Perry</style></notes></record></records></xml>