Welcome to the lab
What we do
Skeletal muscle is a plastic tissue that has the capacity to hypertrophy or atrophy under different metabolic conditions. Dynamic changes in muscle mass have a vital role in physiological, metabolic and physical function in diverse populations ranging from healthy individuals to patients with chronic disease (including cancer, cardiovascular disease, chronic obstructive pulmonary disease). There are numerous factors that can influence changes in muscle mass including nutrition and fitness capacity.
The Integrative Metabolism and Body Composition (IMBC) Lab focuses on understanding the interrelationship between nutrition, exercise, body composition and metabolism. We assess changes in muscle health (i.e., the size and composition of muscles) over the course of metabolic conditions such as cancer, critically illness, kidney and liver disease. Our research program examines potential underlying mechanisms for the development of poor muscle health throughout the disease time-course with the goal of informing rehabilitative and nutrition approaches to counter, and potentially prevent, muscle loss. We integrate concepts of nutrition, protein metabolism, and muscle physiology to improve or maintain muscle health in clinical conditions and through the aging process.