Predicting escitalopram exposure to breastfeeding infants: integrating analytical and in silico techniques

Tuesday, April 3, 2018

"Predicting escitalopram exposure to breastfeeding infants: integrating analytical and in silico techniques", has been accepted for publication in Clinical Pharmacokinetics.

This manuscript presents a workflow for integrating breastmilk concentrations, feeding schedules and infant exposure through physiologically-based pharmacokinetic modelling for the purpose of hazard assessment. The work is the collaboration of SickKids in Toronto and The Pharmacokinetics Research Group (Edginton) at University of Waterloo.