This work introduces a microfluidic-enabled strategy for the controlled fabrication of magneto-responsive hydrogel microbeads, offering a versatile platform for next-generation biomedical and tissue engineering applications.
𝐊𝐞𝐲 𝐡𝐢𝐠𝐡𝐥𝐢𝐠𝐡𝐭𝐬:
✅ A microfluidic droplet-based fabrication approach coupled with in situ gelation in a heated oil column for precise microcarrier engineering
✅ Development of a semi-interpenetrating polymer network (gelatin-based) integrated with Fe₃O₄ nanoparticles, imparting strong magnetic responsiveness
✅ Tunable porosity and mechanical behavior achieved through controlled gelation kinetics, validated via structural and rheological analyses
✅ Strong superparamagnetic characteristics enabling remote magnetic manipulation and responsive functionality
✅ Excellent biocompatibility with enhanced cell adhesion and proliferation, supporting potential in targeted cell delivery and regenerative medicine
Congratulations to the authors: Sayan Ganguly, Fatemeh Parniani, Li Yan Wong, Xiaowu Shirley Tang