Publications

Soley, J.; Taylor, S. D. Synthesis of ß-Hydroxy-α,α-difluorosulfonamides from Carbanions of Difluoromethanesulfonamides. J. Org. Chem. 2021doi.org/10.1021/acs.joc.1c00378.

Diamandas, M.; Moreira, R.; Taylor, S. D. Solid Phase Total Synthesis of Dehydrotryptophan-Bearing Cyclic Peptides Tunicyclin B, Sclerotide A, CDA3a and 4a using a Protected beta-Hydroxytryptophan Building Block. Org. Lett. 2021, DOI: 10.1021/acs.orglett.1c00717

Moreira, R.; Wolfe, J.; Taylor, S. D. A High-yielding Solid-Phase Total Synthesis of Daptomycin using a Fmoc SPPS Stable Kynurenine Synthon. Org. Biomol. Chem. 2021, https://doi.org/10.1039/D0OB02504F. Selected for the front cover.

Zheng, B.; Taylor, S. D. Non-Thermoresponsive and Thermoresponsive Cationic Starch for the Flocculation of Oil Sands Mature Fine Tailings. Energy Fuels, 2021, 35, 6, 5163–5171.

Moreira, R.; Noden, M.; Taylor, S. D.* Synthesis of Azido Acids and their Application to the Preparation of Complex Peptides. Synthesis, 2021, 53, 391-417. Selected for the front cover.

Zheng, B.; Taylor, S. D.* Thermoresponsive Starch for the Flocculation of Oil Sands Mature Fine Tailings. Environ. Sci. Technol. 2020, 54, 21, 13981–13991.

Moreira, R.; Taylor, S. D.* Highly Efficient and Enantioselective Syntheses of (2S,3R)-3-Alkyl- and Alkenylglutamates from Fmoc-Protected Garner’s Aldehyde. Amino Acids 2020, 52, 987-998.

Kralt, B.; Moreira, R.; Palmer, M.; Taylor, S. D.* Total Synthesis of Analogs of A54145D and A54145A1 for Structure-Activity Relationship Studies. J. Org. Chem. 2020, 85, 4, 2213-2219.

Soley, J.; Taylor, S. D.* A Mild, Rapid, Chemo- and Regioselective Procedure for the Introduction of the 9-Phenyl-9-fluorenyl Protecting Group into Amines, Acids, Alcohols, Sulfonamides and Amides. J. Org. Chem. 2020, 85, 4, 2068-2081.

Mohamady, S.; Ismaila, M. I.; Mogheith, S. M.; Attiac, Y. M.; Taylor, S. D. Discovery of 5-Aryl-3-Thiophen-2-yl-1H-Pyrazoles as a New Class of HSP90 Inhibitors in Hepatocellular Carcinoma. Bioorg.Chem., 2020, 103433.

Moreira, R.; Diamandas, M.; Taylor, S. D.* Synthesis of Fmoc-protected amino alcohols via the Sharpless asymmetric aminohydroxylation reaction using FmocNHCl as the nitrogen source. J. Org. Chem. 2019, 84, 15476-15485.

Kralt, B.; Moreira, R.; Palmer, M.; Taylor, S. D.* Total synthesis of A5145 factor D. J. Org. Chem. 2019, 84, 12021-12030.

Noden, M.; Moreira, R.; Huang, E.; Yousef, A.; Palmer, M.; Taylor, S. D.* Total Synthesis of Paenibacterin and its AnalogsJ. Org. Chem., 2019, 8, 5339-5347.

Zheng, B.; Karski, M.; Taylor, S. D.* Thermoresponsive hydroxybutylated starch nanoparticles.  Carbohydr. Polymers, 2019, 206, 145-151.

Moreira, R.; Barnawi, G.; Beriashvili, D.; Palmer, M.; Taylor, S. D.* The effect of replacing the ester bond with an amide bond and of overall stereochemistry on the activity of daptomycin.  Bioorg. Med. Chem. 2019, 27, 240-246.

Mohamady, S.; Taylor, S. D.* Synthesis of nucleoside‐5′‐O‐tetraphosphates from activated trimetaphosphate and nucleoside‐5′‐O‐monophosphates, Curr. Protoc. Nucleic Acid Chem. 2018, doi: 10.1002/cpnc

Moreira, R.; Taylor, S. D.* Asymmetric synthesis of Fmoc-protected β-hydroxy and β-methoxy amino acids via a Sharpless aminohydroxylation reaction using FmocNHCl. Org. Lett. 2018, 20, 7717–7720.

Mohammady, S.; Kralt, B,; Samwel, S. K.; Taylor, S. D. Efficient one-Pot, two-component modular synthesis of 3,5-disubstituted pyrazoles. ACS Omega, 2018, 3, 15566–15574.

Beriashvili, D.; Taylor, R.; Kralt, B.; Abu Mazen, N.; Taylor, S. D.; Palmer, M.* Mechanistic studies on the effect of membrane lipid acyl chain composition on daptomycin pore formation.  Chem Phys Lipids. 2018, 216, 73–79.

Barnawi, G.; Noden, M.; Taylor, R.; Lohani, C.; Beriashvili, D.; Palmer, M*.; Taylor, S. D.* An Entirely Fmoc Solid Phase Approach to the Synthesis of Daptomycin Analogs.  Biopolymers: Peptide Sci. 2018,doi: 10.1002/bip.23094 .

Cho, Y.; Taylor, S.; Aziz, H.* Increased Electromer Formation and Charge Trapping in Solution-processed versus Vacuum-deposited Small Molecule Host Materials of Organic Light-emitting Devices. ACS Applied Materials & Interfaces, 2017, 9, 40564–40572.

Soley, J.; Chiu, E.; Chung, R.; Green, J.; Hein, J. E.; Taylor, S. D.* Synthesis of β‑Ketosulfonamides Derived from Amino Acids and Their Conversion to β‑Keto-α,α-difluorosulfonamides via Electrophilic Fluorination. J. Org. Chem. 2017, 82, 11157–11165.

Taylor, R.; Beriashvili, D.; Taylor, S.*; Palmer, M.* Daptomycin Pore Formation Is Restricted by Lipid Acyl Chain Composition.  ACS Infect. Dis. 2017, 3, 797-801.

  

Taylor, R. M.; Scott, B.; Taylor, S.*; Palmer, M.*  An Acyl-Linked Dimer of Daptomycin Is Strongly Inhibited by the Bacterial Cell Wall. ACS. Infect. Dis. 2017, 3, 462-466.

Lohani, C. R.; Soley, J.; Kralt, B.; Palmer, M.; Taylor, S. D.* alpha-Azido esters in depsipeptide synthesis: C-O bond cleavage during azido group reduction. J. Org. Chem., 2016, 81, 11831-11840.

Mohamady, S.; Taylor, S. D.* One flask synthesis of 2',3'-cyclic nucleoside monophosphates from unprotected nucleosides using activated cyclic trimetaphosphate. Tetrahedron Lett. 2016, 57, 5457-5459.

Lohani, C. R.; Taylor, S. D.* A fresh look at the Staudinger reaction on azido esters: Formation of 2H-1,2,3-triazol-4-ols from alpha-azido esters using trialkylphosphines. Org Lett. 2016, 18, 4412-4415.

McCluskey, G., Mohamady, S.; Taylor, S. D.; Bearne, S. L.* Exploring the potent inhibition of CTP synthase by gemcitabine 5'-triphosphate. ChemBioChem, 2016, 17, 2240-2249 Selected by the editors as a very important paper and for the front cover.

Palmer, M.*; Taylor, S. D.* The action mechanism of daptomycin. Bioorg. Med. Chem. 2016, 24, 6253-6268. Invited review.

Taylor, R.; Butt, K.; Scott. B.; Zhang, T.; Muraih, J. K.; Mintzer, E.; Duhamel, J.; Taylor, S. D.;* Palmer, M.* Two succesive Ca+2-dependent transitions medite membrane binding and oligomerization of daptomycin and the related antibiotic A54145. Biochim. Biophys. Acta – Biomembranes, 2016, 1858, 1999-2005.

Zhang, T.; Taylor, S. D.;*, Palmer, M.;* Duhamel, J.* Membrane Binding and Oligomer Formation by the Calcium-Dependent Lipopeptide Antibiotic A54145: A Quantitative Study with Pyrene Excimer Fluorescence. Biophys. J. 2016, 111, 1267-1277.

Lohani, C. R.; Rasera, B.; Scott, B.; Palmer, M.; Taylor, S. D.* αlpha-Azido acids in solid-phase peptide synthesis: Compatibility with Fmoc chemistry and an alternative approach to the Solid phase synthesis of daptomycin analogs. J. Org. Chem., 2016, 81, 2624-2628.

Mohamady, S.; Taylor, S.D.* Synthesis of nucleoside triphosphates from 2'-3'-protected nucleosides using trimetaphosphate. Org Lett. 2016, 18, 580-583.

Lohani, C.R.; Taylor, R.; Palmer, M.; Taylor, S.D.* Solid-phase total synthesis of daptomycin and analogs. Org Lett. 2015, 17, 748-751.

Lohani, C.R.; Taylor, R.; Palmer, M.; Taylor, S.D.* Solid-phase synthesis and in vitro biological activity of a Thr4→Ser4 analog of daptomycin. Bioorg Med Chem Lett. 2015, 25, 5490-5494.

Mostafa, Y.A. Kralt, B.; Rao, P.P.; Taylor, S.D.* A-ring substituted 17β-arylsulfonamides of 17β-aminoestra-1,3,5(10)-trien-3-ol as highly potent reversible inhibitors of steroid sulfatase. Bioorg Med Chem. 2015, 23, 5681-5692.

Zhang, T.; Muraih, J. K.; Tishbi, N.; Herskowitz, J.; Victor, R. L.; Silverman, J.; Uwumarenogie, S.; Taylor, S. D.; Palmer,* M.; Mintzer, E. Cardiolipin prevents membrane translocation and permeabilization by daptomycin.  J. Biol. Chem. 2014, 289, 11584-11591.

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Mohamady, S.; Taylor, S.D.* Synthesis of 2’-deoxynucleoside-5’-tetraphosphates containing terminal fluorescent labels via activation of cyclic trimetaphosphate. J. Org. Chem., 2014, 79, 2308–2313.

Mohamady, S.; Taylor, S. D. Synthesis of nucleoside tetraphosphates and dinucleoside pentaphosphates via activation of cyclic trimetaphosphate. Org. Lett. 2013, 2612-2615.

Zhang, T,; Muraih, J. K.; Mintzer, E.; Tishbi, N.; Desert, C.; Silverman, J.; Taylor, S. D.; Palmer, M. Mutual inhibition through hybrid oligomer formation of daptomycin and the semisynthetic lipopeptide antibiotic CB-182,462.  Biochim Biophys Acta. 2013, 1828, 302-308.

 

Mostafa, Y.; Taylor, S. D. Steroid Derivatives as Inhibitors of Steroid Sulfatase. J. Steroid Biochem. Mol. Biol. 2013, 137, 183-198.

Mohamady, S.; Taylor, S. D. Rapid and Efficient Synthesis of Nucleoside Polyphosphates and Their Conjugates using Sulfonyl Imidazolium Salts.  Curr. Prot. Nucl. Acid Chem. 2012, Chapter 13:Unit13.11.

Mostafa, Y.; Taylor, S.D. 17-beta-Sulfonamides of 17-beta-aminoestra-1,3,5(10)-trien-3-ol as highly potent inhibitors of steroid sulfatase. Bioorg. Med. Chem. 2012, 20, 1535-1544.

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Mohamady, S.; Taylor, S. D.  Sulfonyl imidazolium salts as reagents for the rapid and efficient synthesis of nucleoside polyphosphates and their conjugates. Org. Lett. 2012 14, 402-405.

Muraih, J. K.; Harris, J.; Taylor, S. D.; Palmer, M. Characterization of daptomycin oligomerization with perylene excimer fluorescence: Stoichiometric binding of phosphatidylglycerol triggers oligomer formation. Biochem. Biophys. Acta - Biomembranes. 2012, 1818, 673-678.

Phan, C-M.; Liu, Y.; Kim, B-M.; Mostafa, Y., Taylor, S. D. Inhibition of steroid sulfatase with 4-substituted estrone and estradiol derivatives. Bioorg. Med. Chem. 2011, 19, 5999-6005.

Mohammady, S.; Taylor, S. D. A General Procedure for the Synthesis of Dinucleoside Polyphosphates. J. Org. Chem. 2011, 76, 6344-6349.

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Desoky, A. Y.; Taylor, S. D. Rapid and efficient chemoselective and multiple sulfations of phenols using sulfuryl imidazolium salts. Tetrahedron Lett. 2011, 52, 3353-3357.

Harris, J.; Taylor, S. D. Efficient synthesis of 17-b-amino steroids. Steroids, 2011, 76, 1098-1102.

Desoky, A. Y.; Hendel, J.; Ingram, L.; Taylor, S. D. Preparation of trifluoroethyl- and phenyl-protected sulfates using sulfuryl imidazolium salts. Tetrahedron, 2011, 67, 1281-1287.

Ali, A. M.; Taylor, S. D.  Synthesis of disulfated peptides corresponding to the N-terminus of chemokines receptors CXCR6 (CXCR61-20) and DARC (DARC8-42) using a sulfate protecting group strategy.  J. Peptide Science, 2010, 16, 190-199.

Desoky, A.; Taylor, S. D. Multiple and Regioselective Introduction of Protected Sulfates into Carbohydrates using Sulfuryl Imidazolium Salts. J. Org. Chem. 2009, 74, 9406-9412.

Ingram, L. J.; Desoky, A.; Ali, A. M.; Taylor, S. D. O- and N-Sulfations of Carbohydrates Using Sulfuryl Imidazolium Salts. J. Org. Chem. 2009, 74, 6479-6485. (Featured article)

Ahmed, V.; Liu, Y.; Taylor, S. D. Multiple Pathways for the Irreversible Inhibition of Steroid Sulfatase with Quinone Methide-Generating Suicide Inhibitors. ChemBioChem, 2009, 10, 1457-1461.

Ali, A. M., Hill, B., Taylor, S. D. The trichloroethyl group as a protecting group for sulfonates and its application to the synthesis of a disulfonate analog of the tyrosine sulfated PSGL-143-50 peptide”.  J. Org. Chem. 2009, 73, 3584-3586.

Ali, A. M.; Taylor, S. D.  Efficient Solid Phase Synthesis of Sulfotyrosine Peptides using a Sulfate Protecting Group Strategy.  Angew. Chem. Int. Ed., 2009, 48, 2024-2026.

Taylor, S. D*; Lunn, F. A.; Bearne, S. L. Ground State, Intermediate, and Multivalent Nucleotide Analogue Inhibitors of Cytidine Triphosphate Synthase. ChemMedChem, 2008, 3, 1853-1857.

Hussain, M.; Ahmed, V.; Hill, B.; Ahmed, Z.; Taylor, S. D. A re-examination of the difluoromethylenesulfonic acid group as a phosphotyrosine mimic for PTP1B inhibition.  Bioorg. Med. Chem. 2008, 16, 6764-6777

Taylor, S. D.; Mirzaei, F.; Bearne, S. Bismethylene Triphosphate Nucleotides of Uridine-4-Phosphate Analogues – A New Class of Anionic-Pyrimidine Nucleotide Analogues. J. Org. Chem. 2008, 73, 1403-1412.

Liu, Y.; Kim, B.; Taylor, S. D. Synthesis of 4-Formyl Estrone using a Positional Protecting Group and its Conversion to other C-4-Substituted Estrogens. J. Org. Chem. 2007, 72, 8824-8830.

Navidpour, L. Lu., W.; Taylor, S.D. “Synthesis of a-Fluorosulfonate and a-Fluorosulfonamide Analogues of a Sulfated Carbohydrate.” Org. Lett., 2006, 8, 5617-5620.

Taylor, S.D.; Mirzaei, F.; Sharifi A.; Bearne, S.L. “Synthesis of Methylene- and Difluorometh-ylenephosphonate Analogs of Uridine-4-Phosphate and 3-Deazauridine-4-Phosphate.” J. Org. Chem.  2006, 71, 9420-9430.

Ahmed, V.; Liu, Y.; Silvestro, C.; Taylor, S.D. “Boronic Acids as Inhibitors of Steroid Sulfatase.”  Biooorg. Med. Chem., 2006, 14, 8564-8573.

Hill, B; Ahmed, V.; Bates, D.; Taylor, S.D. “Enantioselective Synthesis of Protected L-4-[Sulfonamido(difluoromethyl)]phenylalanine and L-4-[Sulfonamido(methyl)]phenylalanine and an Examination of Hexa- and tripeptide platforms for evaluating pTyr Mimics for PTP1B Inhibition.”  J. Org. Chem. 2006; 71, 8190-8197.

Taylor, S.D.; Mirzaei, F.; Bearne, S.L. “An Unsymmetrical Approach to the Synthesis of Bis-Methylene Triphosphate Analogues.” Org. Lett. 2006, 8, 4243-4246.

Ingram, L.; Taylor, S. D. “Introduction of 2,2,2-Trichloroethyl-Protected Sulfates into Monosaccharides using a Sulfuryl Imidazolium Salt and it’s application to the Synthesis of Sulfated Carbohydrates.”  Angew. Chem. Int. Ed. Engl., 2006, 3503-3506.

Cecchi, A.; Taylor, S.D.; Liu, Y.; Hill, B.; Vullo, D.; Scozzafava, A.; Supuran, C.T. “Carbonic anhydrase inhibitors: Inhibition of the human enzyms I, II, VA and IX with a library of substituted difluoromethanesulfonamides.” Bioorg. Med. Chem. Lett. 2005, 15, 5192-5196.

Liu, Y.; Ahmed, V.; Hill, B.; Taylor, S.D. “Synthesis of a non-hydrolyzable estrone sulfate analogue bearing the difluoromethanesulfonamide group and its evaluation as a steriod sulfatase inhibitor.” Org. Biomol. Chem. 2005, 3, 3329-3335.

Ahmed, V.; Ispahany, M.; Ruttgaizer, S.; Guillemette, G.; Taylor, S.D. "A fluorogenic substrate for the continuous assaying of aryl sulfatases."  Anal. Biochem. 2005, 340, 80-88.

Lu, Wallach; Navidpour, L.; Taylor, S.D. "An Expedient Synthesis of Benzyl 2,3,4-tri-O-benzyl-b-D-glucopyranoside and Benzyl-2,3,4-tri-O-benzyl-b-D-mannopyranoside." Carbohydrate Res. 2005, 340, 1213-1217.

Hill, B.; Liu, Y.; Taylor, S. D. "Synthesis of a-Fluorosulfonamides by Electrophilic Fluorination." Org. Lett. 2004, 6, 4285-4288. 

Taylor, S. D.; Hill, B. "Recent Advances in PTP1B Inhibitors."  Expert Opinion on Investigational Drugs, 2004, 13, 199-214 (invited review article).

Liu, Y.; Lien, I-F. F.; Ruttgaizer, S.; Dove, P.; Taylor, S. D. " Synthesis and Protection of Aryl Sulfates Using the 2,2,2-Trichloroethyl Moiety." Org. Lett. 2004, 6, 209-212.

Lapierre, J.; Ahmed, V.; Chen, M-J.; Ispahany, I.; Guillemette, J. G.; Taylor, S. D. The Difluoromethylene Group as a Replacement for the Labile Oxygen in Steroid Sulfates: A New Approach to Steroid Sulfatase Inhibitors." Bioorg. Med. Chem. Lett. 2004, 14, 151-155.

St. Maurice, M.; Bearne, S. L.; Lu, W.; Taylor, S.D. Inhibition of Mandelate Racemase by a-Fluorophophonates. Bioorg. Med. Chem. Lett. 2003, 13, 2041-2044.

Taylor, S. D. "Inhibitors of Protein Tyrosine Phosphatase 1B."  Current Topics in Medicinal Chemistry, 2003, 3, 759-782  (invited review article).

Hum, G.; Lee, J.; Taylor, S. D. "Synthesis of [Difluoro-(3-alkenylphenyl)-methyl]-phosphonic acids on non-crosslinked polystyrene and their evaluation as inhibitors of PTP1B." Bioorg Med Chem. 2002, 12, 3471-3475.

Leung, C.; Lee, J.; Meyer, N., Jia, C.; Grzyb, J.; Liu, S.; Hum G.; Taylor, S. D. "The difluoromethylenesulfonic acid group as a monoanionic phosphate surrogate for obtaining PTP1B inhibitors.” Bioorg. Med. Chem. 2002, 10, 2309-2323.

Jia, Z.; Ye, Q.; Dinaut, A.N.; Wang, Q.; Waddleton, D.; Payette, P.; Ramachandran, C.; Kennedy, B.; Hum, G. Taylor, S.D. “Structure of Protein Tyrosine Phosphatase 1B in Complex with Inhibitors Bearing Two Phosphotyrosine Mimetics.”  J. Med. Chem. 2001, 44, 4584-4594.

Dinaut, A.N.; Taylor, S.D. “Antibody-Catalyzed Activation of a Model Tripartate Prodrug by a Tandem hydrolysis-1,6-Elimination Reaction.” J. Chem. Soc. Chem. Commun. 2001, 1386-1387.

Liu, S.; Dockendorf, C.; Taylor, S.D. “Synthesis of Protected L-4-[Sulfono(difluoromethyl)]phenylalanine and its Incorporation into a Peptide.”  Org. Lett. 2001, 3, 1571-1574.

Hum, G.; Wooler, K.; Lee, J.; Taylor, S.D. “Cyclic Five-Membered Phosphinate Esters as Transition State Analogues for Obtaining Phosphohydrolase Antibodies.”  Can. J. Chem., 2000, 78, 642-655.

Hum, G.; Grzyb, J.; Taylor, S.D. “Synthesis of Non-Peptidyl a,a-Difluoromethylenephosphonic Acids on a Soluble Polymer Support.” J. Combi. Chem., 2000, 2, 234-242.

Dinaut, A. N.; Chen, M-J.; Lea, M. Marks, A.; Taylor, S. D. “Antibody-Catalyzed Hydrolysis of an N-Methyl Carbamate.” J. Chem. Soc. Chem. Commun, 2000, 385

Kotoris, C.; Wen, W.; Taylor, S. D. “Preparation of Chiral a-Monofluorophosphonic Acids and Their Evaluation as Inhibitors of Protein Tyrosine Phosphatases.”  J. Chem. Soc. Perkin Trans. I, 2000, 1271.

Taylor, S. D.; Kotoris, C.; Hum. G. H. Recent Advances in Electrophilic Fluorination. Tetrahedron, 1999, 55, 12431-12477.

Batey, R. A.; Yoshina-Ishii, C.; Taylor, S. D.*; Santhakumar, V., A New Protocol for the Formation of Carbamates using Carbamoyl Imidazolium Salts. Tetrahedron Lett., 1999, 40, 4149-4152.

Chen, M-J.; Taylor, S. D, Synthesis of Estrone-3-Sulfate Analogues Bearing Novel Non-Hydrolyzable Sulfate Mimetics. Tetrahedron Lett., 1999, 40, 2669-2671.

Kotoris, C.; Chen, M-J.; Taylor, S. D.*, Novel Phosphate Mimetics for the Design of Non-Peptidyl Inhibitors of Protein Tyrosine Phosphatases. Biooorg. Med. Chem. Lett., 1998, 8, 3275-3280.

Kotoris, C.; Chen, M-J.; Taylor, S. D.*, Preparation of Benzylic alpha-Difluoronitriles, -tetrazoles and -sulfonates via Electrophilic Fluorination. J. Org. Chem., 1998, 63, 8052-8057.

Taylor, S. D.*; Kotoris, C. C., Dinaut, A. N.; Ramachandran, C.; Huang, Z.; Wang, Q., Potent Non-Peptidyl Inhibitors of Protein Tyrosine Phosphatase 1B. Bioorg. Med. Chem., 1998, 6, 1457-1468.

Batey, R. A.; Santhakumar V.; Yoshina-Ishii, C.; Taylor, S. D., An Efficient New Protocol for the Formation of Unsymmetrical Tri- and Tetrasubstituted Ureas. Tetrahedron Lett. 1998, 39, 6267-6270.

Taylor, S. D.; Kotoris, C., Dinaut, A. N.; Chen, M-J., Synthesis of Aryl(Difluoromethylenephosphonates) via Electrophilic Fluorination of a-Carbanions of Benzylic Phosphonates with N-Fluorobenzenesulfonimide. Tetrahedron, 1998, 54, 1691-1714.

Wang, Q.; Huang, Z.; Ramachandran, C.; Dinaut, A. N.; Taylor, S. D., Bis[a,a-Difluoromethylenephosphonate]Naphthalenes as Potent Inhibitors of Protein Tyrosine Phosphatases. Bioorg. Med. Chem. Lett. 1998, 8, 345.

Taylor, S. D.; Chen, M-J.; Dinaut, A. N.; Batey, R. A., A Versatile and General Method for the Synthesis of N,O-Aryl Phosphoramidates and its Application to the Synthesis of Transition State Analogues for Carbamate Hydrolysis. Tetrahedron, 1998, 54, 4223-4242.

Xiaobo, G.; Batey, R. A.; Taylor, S. D.; Hum, G. Jones, J. B., The Synthesis of Dienecarbamates as ADAPT Prodrug Models. Synthetic Communications 1997, 27, 2445-2453.

Taylor, S. D.; Dinaut, A. N.; Thadini, A. N.; Huang, Z., Synthesis of Benzylic Mono(a,a-Difluoromethylphosphonates) and Benzylic Bis(a,a-Difluoromethylphosphonates) via Electrophilic Fluorination. Tetrahedron Lett. 1996, 45, 8089-8092.

Anderson, G. T.; Alexander, M. D.; Taylor, S. D.; Smithrud, D. B.; Benkovic, S. J. Weinreb, S. M., Catalytic Antibodies in Synthesis: Design and Synthesis of a Hapten for Application to the Preparation of a Scalemic Pyrrolidine Ring Synthon for Ptilomycalin A. J. Org. Chem. 1996, 61, 125-132

Liotta, L. J.; Gibbs, R. A.; Taylor, S. D.; Benkovic, P. A.; Benkovic, S. J., Antibody-Catalyzed Rearrangement of a Peptide Bond:  Mechanistic and Kinetic Investigations.  J. Am. Chem. Soc. 1995, 117, 4729-4741.

Hirschmann, R.; Smith, A. B.; Taylor, C. M.; Benkovic, P. A.; Taylor, S. D.; Yager, K. M.; Sprengler  P. A.; Benkovic, S. J.,  Peptide Synthesis Catalyzed by an Antibody Containing a Binding Site for Variable Amino Acids. Science 1994, 265, 234-237.

Taylor, S. D.; Kluger, R., Hydrolysis of Methylacetoin Ethyl Phosphate.  Competing Pathways for Carbonyl Hydrate Participation in a Model for Biotin Carboxylation. J. Am. Chem. Soc. 1993, 115, 867-871.

Gibbs, R. A.; Taylor, S. D.; Benkovic, S. J., Antibody-Catalyzed Rearrangement of a Peptide Bond. Science 1992, 258, 803-805.

Taylor, S. D.; Kluger, R., Heats of Reaction of Cyclic and Acyclic Phosphate and Phosphonate Esters.  “Strain Discrepancy” and Steric Retardation. J. Am. Chem. Soc. 1992, 114, 3067-3071.

Kluger, R.; Taylor, S. D., Endocyclic Cleavage in the Alkaline Hydrolysis of the Cyclic Phosphonate Methyl Propylphostonate: Dianionic Intermediates and Barriers to Pseudorotation.  J. Am. Chem. Soc. 1991, 113, 5714-5719.

Kluger, R.; Taylor, S. D., Mechanisms of Carbonyl Hydrate Participation in Phosphate Ester Hydrolysis and their Relationship to Mechanisms for the Carboxylation of Biotin. J. Am. Chem. Soc. 1991, 113, 996-1001.

Kluger, R.; Taylor, S. D., On the Origins of Enhanced Reactivity of Five-Membered Cyclic Phosphate Esters.  The Relative Contributions of Enthalpic and Entropic Factors.  J. Am. Chem. Soc. 1990, 112, 6669-6671.