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Automatic algorithm for measuring visually evoked pupil size changes from OCT images

TitleAutomatic algorithm for measuring visually evoked pupil size changes from OCT images
Publication TypeConference Paper
Year of Publication2013
AuthorsLiu, C., A. A. Moyed, A. Wong, P. Fieguth, V. Chan, H. Bie, and K. Bizheva
Conference NameOphthalmic Technologies XXIII, SPIE
Abstract

A new approach to determining the physical size of the pupil, based on the use of a fast scanning, functional ultrahigh resolution OCT and a novel automated computer algorithm was developed. The algorithm tracks the highly reflective edges of the iris in the OCT tomograms by applying a three-step strategy: a) a noise compensation reconstruction for reducing the effect of speckle on the edge tracking accuracy; b) a region-based maximum likelihood tracking; and c) an outlier compensation for calculation of the pupil size. The algorithm was tested on OCT images acquired from visually stimulated chicken.