Course subject: Pharmacy (PHARM)

For more detailed course information, click on a course title below.

Pharmacy (PHARM) 601 MSc Thesis Proposal (0.50) SEM,TUT

Course ID: 014939
This course prepares MSc in Pharmacy students to present their research objectives and proposed methods in written and oral form suitable for an MSc program and involves preparation of a written research proposal and oral defence of the proposal. The written proposal and the oral presentation of the proposal will be considered by an examination committee.

Pharmacy (PHARM) 602 Grant Writing in the Sciences (0.50) LEC

Course ID: 013817
The course is designed to teach the student how to critically review the literature, ask the right scientific questions, generate hypotheses, and write a professional curriculum vita and a fundable grant proposal. The course will include lectures from the instructor and guest speakers, small group discussion, student presentations and a final written grant proposal.

Pharmacy (PHARM) 603 Selected Topics in Medicinal Chemistry (0.50) LEC

Course ID: 013818
This course provides an introduction to basic principles in medical chemistry such as physiochemical properties, drug design and pharmacological actions. A brief overview of the theory and application of computer aided drug design principles will provide a basic understanding of the "in silico" drug design concepts. The student will develop an understanding toward the concepts of peptide/petidomimetic design as therapeutic agents. A series of case studies on clinical drugs will be presented with major emphasis on their design, synthesis, reaction mechanisms and structure-activity relationship studies. A section of the course will address the pathophysiology and pharmacology of diseases affecting the central nervous system. In addition, learning activities and assignments include a term paper submission and in class presentation of current topics in medicinal chemistry.

Pharmacy (PHARM) 604 Gene Therapy (0.50) LEC

Course ID: 013819
Gene therapy offers extraordinary potential to treat both inherited and acquired diseases by using the body's own machinery to produce a therapeutic compound or protein, or up-regulate/down-regulate specific cellular processes. This course will examine the various extra- and intracellular barriers to DNA transfection, and the common vectors used in gene therapy. Various routes of administration, such as injected, inhaled, and transdermal will be discussed in terms of their challengers, and the successes of recent formulations described in the literature.

Pharmacy (PHARM) 605 Physical Chemistry and Application of Surfactants (0.50) LEC

Course ID: 013820
Surface active compounds, more commonly known as surfactants are found in nearly every aspect of day to day life, including motor oils, pharmaceuticals, cosmetics, detergents, and paints and inks to name a few. This course will introduce the student to the structures of classical and emerging classes of surfactants and their fundamental properties that make these systems so useful. The self-assembly of these compounds into micelles will be discussed in detail using both thermodynamic and kinetic modules and modern methods of characterizing these systems will be examined. The application of surfactants in a variety of industries will be introduced. The capstone activity of this course will entail a critical analysis of a relevant recent journal article, and presentation to the class.

Pharmacy (PHARM) 606 Neuroscience in the 21st Century (0.50) LEC

Course ID: 013821
Intensively examines medical and technological advances in neuroscience. Students will first develop a deep understanding of the structure and function of the central nervous system, neuronal cell biology and physiology, and neurotransmission. Explores selected CNS disease states and identify mechanisms of neuropathology by biological, environmental, and iatrogenic causes. Advances in technology and nanotechnology is and will continue to transform the treatment of diseases of the nervous system and these issues will be explored by expert guest lecturers.

Pharmacy (PHARM) 607 Advanced Pharmaceutical Analysis (0.50) LEC

Course ID: 013822
This course provides an introduction to modern spectroscopic methods with emphasis on pharmaceutical analysis. First few lectures will cover the theory and application of UV-Vis and IR spectroscopy. A review of NMR spectroscopy will focus on commonly used techniques such as 1H NMR and 13C NMR and their application. The student will get a practical experience in spectroscopic methods for structural elucidation by using UVS-VIS, IR and NMR spectrometers. In addition, a section will address the theory and application of mass spectrometry. Examples of drug molecules/pharmaceuticals and their spectroscopic characteristics will be discussed. In addition, learning activities and assignments include problem sets and structural elucidation of an unknown organic molecule.

Pharmacy (PHARM) 608A Selected Topics in Pharmaceutical Sciences 1 (0.50) LEC,RDG,TUT

Course ID: 013919
This course will discuss specialized topics that are related to the research interests of faculty members in the field of Pharmaceutical Sciences. Topics could include, for example, the areas of drug delivery systems, diabetes, bacteriophage derived therapeutics, central nervous disorders, medicinal chemistry, pharmacokinetics, biophysical methods, bionanotechnology, nanomedicine among others. This course may be presented in any of the following formats, reading based, lecture based, project based or online learning.

Pharmacy (PHARM) 609 Advanced Pharmacokinetics (0.50) LEC

Course ID: 014082
This course provides statistical hands-on knowledge for the implementation of nonlinear mixed effects (NLME) models in the analysis of population pharmacokinetic data. In order to provide a foundation for NLME, the content builds from simple to multiple linear regression models and to linear mixed effects models. Exploratory and descriptive analyses as well as model implementation will be taught in R and Phoenix.

Pharmacy (PHARM) 610 Topics in Drug Development (0.50) LEC

Course ID: 014083
This course will cover all aspects of drug development, from basic research through to post-marketing surveillance of drug safety and efficacy. Faculty members from the UW School of Pharmacy and beyond will provide their expertise on aspects of the drug development process. Students will gain valuable knowledge and appreciation of the drug development process from "bench to bedside". Using real-life drug research problems, students will learn how identification of disease stat pathophysiology directs drug design, how medicinal chemistry optimizes lead molecule creation, how drug dosage forms are designed, pharmacokinetic studies, how animal models are used to test the efficacy and toxicity of lead compounds, the design and evaluation of clinical trials, drug manufacturing, perspectives from the pharmaceutical industry, as well as business and regulatory issues.

Pharmacy (PHARM) 611 Special Topics in Pharmacy Practice (0.50) LEC,RDG,SEM,TUT

Course ID: 014366
This course will discuss specialized topics that are of mutual interest to the research of faculty members and graduate students in the field of Pharmacy Practice. Topics could include, for example, pharmacy education; rural pharmacy practice; geriatrics and aging; pharmacoepidemiology; the role of technology in primary care; chronic disease management; expanded scope of practice; collaborative practice in different settings; health services design and care delivery; among others. This course may be presented in any of the following formats, reading based, lecture based, project based, or online learning.

Pharmacy (PHARM) 613 Principles and Practices in Systemic Treatments for Cancer (0.50) LEC

Course ID: 014780
This course is designed to accommodate graduate students from a variety of backgrounds who wish to increase their understanding of cancer and its treatment. It will cover the full range of issues involved in the rational use of anti-cancer agents, from the older cytotoxic drugs through to newer agents targeted at particular steps in cell regulatory pathways. A broad overview of the pathology of cancer is included. Although drug mechanisms will be addressed, there is an equivalent emphasis on what these drugs mean to the patient. Students will consider the disease itself, the behavior of the diagnosed patient, the issues around drug administration, the extensive side effects and the various supportive strategies that are required to take the patient through the very stressful course of systemic cancer therapy.

Pharmacy (PHARM) 614 Systematic Review and Meta-Analysis (0.50) LEC,TUT

Course ID: 014953
This course will provide students with an overview of the rationale and stages involved in the conduct of a formal systematic review and meta-analysis of a well-defined clinical/health research question. The overarching aim is to provide students with the tools to critically appraise and conduct a systematic review and meta-analysis. Students will largely work in pairs to progress through each step involved (with feedback from instructors at each stage) and to produce a final systematic review and meta-analysis to be presented/submitted at the end of the course. Course Objectives: 1. To demonstrate an understanding of the rationale underlying a systematic review and meta-analysis and relevance to clinical care and health policy; 2. To critically appraise a systematic review; 3. To develop a focused research question amenable to a systematic review; 4. To develop and implement a comprehensive and systematic literature search strategy; 5. To determine and apply procedures for including/excluding potential studies for a systematic review and meta-analysis; 6. To develop and implement a data abstraction process and study database; 7. To demonstrate an understanding of the fundamental statistical/biostatistical issues relevant to the conduct of a formal systematic review and meta-analysis. 8. To perform statistical analyses for a systematic review and meta-analysis and complete/present a final report demonstrating all stages involved. Students will need to meet with Course Coordinators and provide of appropriate previous experience with linear and/or logistic regression techniques.

Pharmacy (PHARM) 615 Strategic Management of Biopharmaceutical Technology (0.50) LEC,TUT

Course ID: 014959
The strategic development and commercialization of novel and incremental bio/pharma technological innovation is rapidly expanding across all industries and with it comes the need for adept management of the process. Effective management involves ensuring technological precaution such that the risks and ambiguities associated with advanced technologies are minimized. Additionally, management must be strategic to maximize the successful achievement of corporate objectives based on the alignment of internal resources with the external environment. The transfer of technology from lab to market and successful propagation is usually impeded by a lack of cohesion between scientific understanding and business adeptness. This course also serves to analyse and connect scientific principles underlying novel and incremental technologies with strategic management and the commercialization process from an entrepreneurial perspective.

Pharmacy (PHARM) 616A PhD Thesis Proposal (0.50) SEM,TUT

Course ID: 015241
This course prepares PhD in Pharmacy students to present their research objectives and proposal methods in written and oral form suitable to a PhD program and involves the preparation of a written research proposal and oral defence of the proposal. The written and oral proposal will be considered by an examination committee that normally includes the student's Thesis Advisory Committee plus an independent Chair. This course is only available for the first Thesis Proposal taken within the Pharmacy Program.

Pharmacy (PHARM) 616B PhD Thesis Proposal (0.00) SEM,TUT

Course ID: 016246
This course prepares PhD in Pharmacy students to present their research objectives and proposal methods in written and oral form suitable to a PhD program. The written and oral proposal will be considered by an examination committee that normally includes the student's Thesis Advisory Committee plus an independent Chair. This course is for students who previously completed Pharm 601 in their MSc in Pharmacy program and are required to fulfill a second Thesis Proposal where no additional course credit is available.

Pharmacy (PHARM) 617 Formulations (0.50) LEC,SEM

Course ID: 015361
The formulation of chemicals into products for specific purposes dates back to the stone age. Formulated products are now part of everyday life and include pharmaceuticals, cosmetics, personal care products, detergents, agricultural products, etc. This course will examine the chemical formulation of various consumer products with an emphasis on pharmaceutical formulations; major components used in formulations, surface chemistry, and molecular interactions will be discussed. Analytical methods for testing formulations, raw materials, and environmental and sustainability considerations will also be discussed.

Pharmacy (PHARM) 618 Applied Health Economics and Pharmacoeconomics (0.50) LEC

Course ID: 015872
This course will take a practical approach to health economics and pharmacoeconomics. Students will learn about relevant methods of evaluating diagnostic and therapeutic strategies in order to optimize individualized patient care and inform policy decision, including those in which a fixed amount of resources are an important consideration. Topics include preference-based measures of health-related quality of life and quality-adjusted life years, key principles of economic evaluation and decision-analytic modeling, and critical appraisal of economic evaluation studies. Students will also learn to use decision analysis software to build and test their own pharmacoeconomics analyses.

Pharmacy (PHARM) 619 Drug Discovery (0.50) LEC

Course ID: 016233
This course provides an opportunity for students to design experiments and carry out independent research projects in the area of neurodegenerative disorders. Student projects are aimed to study the pathophysiology of Alzheimer┬┐s disease and related neurodegenerative disorders by various techniques such as designing novel small molecules and peptides by computational chemistry. Furthermore, the interactions between small molecules/peptides with misfolded proteins/peptides will be evaluated by biochemical and biophysical techniques with emphasis on fluorescence spectroscopy and ligand-protein kinetic studies. Microscopy techniques including transmission electron microscopy (TEM) analysis will be studied. Students will be trained in using the computational chemistry software Discovery Studio Structure-Based-Design. Individual student projects may include compound characterization by nuclear magnetic resonance spectroscopy (NMR), high performance-liquid chromatography (HPLC) and liquid chromatography mass spectrometry (LC-MS) techniques. Students are expected to spend between 10-11 weeks in the research lab working on their assigned projects. Course re-requisite include completion and proof of safety training including WHMIS, workplace violence training and safety orientation.

Pharmacy (PHARM) 651 Advanced Principles of Medication Management 1 (0.50) LEC,RDG,TUT

Course ID: 016370
Students will learn advanced principles of drug action, pharmacogenomics, pharmacokinetics and therapeutics and will apply these principles to identifying and resolving drug-related problems in a variety of therapeutic areas. A problem-based learning approach will be used to maximize student learning.

Pharmacy (PHARM) 652 Advanced Principles of Medication Management 2 (0.50) LEC,RDG,TUT

Course ID: 016371
Students will build on the foundational knowledge and skills developed in PHARM 651 Advanced Principles of Medication Management 1.

Pharmacy (PHARM) 653 Methods in Clinical and Applied Research (0.50) LEC

Course ID: 016372
This course will provide an overview of common research methods used to address questions in clinical, applied and translational research. Research ethics and responsible conduct of research will be addressed. This course will touch on basic concepts in successful grant writing.

Pharmacy (PHARM) 654 Critical Appraisal and Evidence-Based Practice (0.50) LEC,SEM

Course ID: 016373
Students will identify and critique papers from the primary drug literature. Skills related to critical appraisal and evidence-based practice will be developed. Students will have the opportunity to develop communications skills related to presenting scientific literature.

Pharmacy (PHARM) 655 Physical Assessment and Clinical Laboratory Testing (0.50) LAB,LEC

Course ID: 016374
Fundamental skills of physical assessment and the interpretation of clinical laboratory tests relevant to monitoring the effects associated with the use of medications will be covered.

Pharmacy (PHARM) 656 Analysis of Quantitative Health Care Data (0.50) LEC

Course ID: 016247
This course is designed to teach students the fundamentals of planning, conducting, and communicating the analysis of quantitative data within the context of applied health research. Students will learn quantitative data analysis through hands-on experience using different sources of data (e.g., clinical trial, cross-sectional survey, prospective cohort, etc.). Topics will include descriptive statistics, t-Test, ANOVA, linear regression, logistic regression, poisson regression, and proportional hazards regression. Several techniques to adjust for confounding will be covered. Students will learn to apply their analytic skills using SAS.

Pharmacy (PHARM) 657 Substance Use in Primary and Community Care (0.50) DIS

Course ID: 016435
In Pharmacy and other health care professions mental health and addictions work is often carried out in specialized settings and is focused on pathological substance use and use disorder. Addictions research is also almost entirely dedicated to substance use disorder and treatment. In most community and primary settings, stigma about substance use presents an additional barrier to addressing the impacts of substance use on disease and medication management. This course focuses on substance use in any form and how it affects disease progression, pharmaceutical care including drug interactions, and public health. We identify traditional and emerging types of research and information, including data from non-medical research sources. Community engagement and the pharmacists becoming a community substance educator will be explored. Drug and drug classes covered include opioids, methamphetamine, cocaine, prescription and other stimulants, GABAergic drugs, serotonergic, glutamatergic, and cholinergic hallucinogens, entactogens, alcohol, nicotine, and cannabis.