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Dr. Zoya Leonenko

Professor
Dr. Zoya Leonenko
519-888-4567 x38273
Location: PHY 354

Department of Physics and Astronomy
University of Waterloo
200 University Avenue West
Waterloo, Ontario, Canada
N2L 3G1

Danielle McRae

NSERC Post Doctoral Fellow
Danielle McRae

Research Interests:

  • AFM applications in membrane biophysics and ion channels study

  • Plasmonics and nanoscale spectroscopy

Leonenko Lab History:

  • 2021-current: NSERC Post Doctoral Fellow

Khadijeh Esmaeilpour

Post Doctoral Fellow
Khadijeh Esmaeilpour

Research Interests:

  • Quantum neuroscience
  • Effect of Li isotopes and ketamine on electrical activity in animal brain slices 

Leonenko Lab History:

  • November 2021- Current: Post Doctoral  Fellow (Quantum Neuroscience)

Dr. Brenda Yasie Lee

Lecturer, Volunteer Research Associate
Brenda Lee
519-888-4567 ext. 39124
Location: PHY 366

Research Interests:

  • Study of antimicrobial peptide daptomycin and its interaction with pulmonary surfactant and model bacterial membranes
  • Study of amyloid-beta interactions with model membranes in relation to Alzheimer's Disease
  • Use of atomic force microscopy, Kelvin probe force microscopy, Langmuir-Blodgett trough, fluorescence spectroscopy and black lipid membrane techniques

Leonenko Lab History:

  • May 2011 - Aug 2011: NSERC USRA Summer Student (Physics)
    * Working with atomic force microscopy imaging of amyloid-beta interactions with SG1 inhibitors
  • Sep 2011 - Dec 2012: Undergraduate Research Volunteer (Biology)
    * Atomic force microscopy imaging of DHA (omega-3) and its effect on amyloid-beta fibril formation
  • Jan 2013 - Apr 2017: PhD Candidate in Biology (Nanotechnology)
  • May 2017 - Aug 2019: Research Associate
  • Sep 2019 - Current: Volunteer Research Associate
Link to profile: Brenda's Bio & Research

Dr. Liz Drolle

Collaborator, Volunteer Research Associate
Liz Drolle

Current Position:

  • Postdoctoral Fellow at University of Waterloo's Centre for Contact Lens Research

Leonenko Lab History:

  • Sep 2010 - Jun 2015: PhD Student (Biology)
  • Jan 2008 - Apr 2010: Undergraduate Research Assistant (Biology)

Research Interests:

  • Investigation of steroid's effect on phospholipid membranes
  • Effect of cholesterol on amyloid fibril formation
  • Study of lipid-protein films found in lens deposits
  • Atomic force microscopy and Langmuir-Blodgett studies

Dr. Robert Henderson

Collaborator, Volunteer Research Associate
Dr. Robbie Henderson

Current Position:

  • MD/MBA Student at University of Saskatchewan

Leonenko Lab History:

  • Sep 2011 - Dec 2015: PhD Student (Physics)
    * Frequency modulated Kelvin probe force microscopy to study electrostatics in lipid-protein assemblies

Carina Filice

Ph.D. Student (Biology)
Carina Filice

Research Interests:

  • Antimicrobial peptides in relation to Alzheimer's Disease
  • Effect of melatonin on amyloid and model monolayers in relation to Alzheimer's disease

Leonenko Lab History:

  • Sep 2018 - Current: PhD Student (Biology)
  • May 2017 - Apr 2018: Undergraduate Honours Student (Biology)

Nanqin (Nancy) Mei

Ph.D. Student (Physics - Nanotechnology)
Nanqin (Nancy) Mei

Research Interests:

  • Studying the effect of melatonin on Alzheimer's disease using localized surface plasmon resonance (LSPR)

Leonenko Lab History:

  • May 2016 - Apr 2017: Undergraduate Honours Student (Physics)
    * Studying the effect of melatonin on Alzheimer's disease using localized surface plasmon resonance (LSPR)

Yue Xu

Ph.D. Student (Physics - Nanotechnology)
Yue Xu

Research Interests:

  • Studying the effect of trehalose and lithium isotopes on lipid model membrane in the background of Alzheimer’s Disease by Black lipid membrane (BLM)
  • Studying the effect of trehalose and lithium isotopes on lipid model membrane in the background of Alzheimer’s Disease by Black lipid membrane (BLM)

Leonenko Lab History:

  • Sep 2019 - Current: PhD Student (Physics - Nanotechnology)
  • Sep 2018 - Aug 2019: Undergraduate Honours Student (Physics)

Irina Bukhteeva

Ph.D. Student (Physics - Nanotechnology)
Irina Bukhteeva

Research Interests:

  • Quantum neuroscience
  • Experimental and theoretical study of Posner molecules as Bio-Qubit candidates

Leonenko Lab History:

  • Sep 2020 - Current: PhD Student (Physics - Nanotechnology)

James Livingstone

Ph.D. Student (Pharmacy)
James Livingstone

Research Interests:

  • Effect of Li in neuronal function

Leonenko Lab History:

  • Fall 2020 - Current: PhD Student (Pharmacy)
  • Fall 2018 - Fall 2020: MSc Student (Biology)
  • Fall 2016 - Spring 2017: Undergraduate Honours Student (Biomedical Sciences)

Kartar Singh

M.Sc. Student (Biology)
Kartar Singh

Research Interests:

  • Molecular neuroscience and mechanisms of neuroprotection in Alzheimer's Disease

Leonenko Lab History:

  • Sep 2020 - Current: MSc Student (Biology)
  • May 2020 - Aug 2020: NSERC Undergraduate Student (Biology)
  • May 2019 - Dec 2019: Undergraduate Honours Student (Biology)

Susana Montoya Jaramillo

MITACS undergraduate visiting student
Susana Montoya Jaramillo

Project:

  • Effect of bacterial and human amyloid cross-seeding on cellular membrane damage
    working with PhD student Carina Filice

Leonenko Lab History:

  • Spring 2023: MITACS undergraduate visiting student (Medicine, Iniversidad de Antioquia, Colombia)

Zhilin Pan

MITACS undergraduate visiting student
Zhilin Pan

Project:

  • Effect of Lithium isotopes on ion channel activity: a search for quantum effects in neuroscience
    working with PhD student Irina Bukhteeva

Leonenko Lab History:

  • Spring 2023: MITACS undergraduate visiting student (Molecular Biol. & Biot., The University of Hong Kong, China)

Past Members

Past Members

Thank you to all our past members for their contributions to the lab!

PUYUAN LIU
Spring 2022
    PHYS 437 Honours Student
Research: Machine learning and BLM data analysis
Currently: ---


RUIXUAN (NICK) XUE
Spring 2022 and Fall 2022
   BIOL 499 Honours Student
Research: Effect of serotonin and melatonin on model membranes
Currently: ---


ERIK HERZ
Spring 2022
   Research Assistant
Fall 2021 and Winter 2022
   PHY 437
Spring 2021
   COOP Student
Research: AFM and force spectroscopy studies of the effect of melatonin in model lipid membranes
Currently: ---


​​​​​YOUSUF OMAR RAMAHI

Spring 2021
    Undergraduate Honours Student (Life Physics)
Fall 2020
    Undergraduate Honours Student (Life Physics)
Research: BLM study of the role of lipid peroxidation in amyloid toxicity in Alzheimer's disease
Currently: NSERC USRA Student


YURII POTSILUIENKO
Spring 2021
    Undergraduate Co-op Student (Physics)
Winter 2021
    Undergraduate Co-op Student (Physics)
Research: Effect of Li on ion channel transport: BLM study
Currently: -----


JINGWEN LIANG
Winter 2021
    Undergraduate Honours Student (Materials & Nanosciences)
Fall 2020 
    Undergraduate Honours Student (Materials & Nanosciences)
Research: Biophysics: Localized surface plasmon resonance study in relation to the effect of melatonin in neuronal model membranes
Currently: -----


JEFFREY GLASIER
Winter 2021
    Undergraduate Co-op Student (Physics)
Research: Effect of Xe isotopes in molecular and quantum biology
Currently: -----


JULIA ISABELLA LUMINI
Winter 2021
    Research Assistant (Physics)
Winter 2020
    BIOL 499 Honors project 
Fall 2019
    BIOL 499 Honors project 
Research: Effect of melatonin on amyloid toxicity, BLM study
Currently: -----


JOSEPH BRENT LAMARRE
Fall 2020
    Undergraduate Honours Student (Physics)
Research: Quantum Biology: Literature review on kinetic effect of Li isotopes 
Currently: -----


GEXU (LEILA) LIU
Fall 2020 - Winter 2021
    Undergraduate Honours Student (Materials & Nanosciences)
Research: Biophysics: BLM study of the effect of melatonin in DPPC/POPC/Cholesterol model membranes in amyloid toxicity in relation to Alzheimer's Disease
Currently: -----


LUNLUN GUAN
Fall 2020 - Winter 2021
    Undergraduate Honours Student (Materials & Nanosciences)
Research: Biophysics: BLM study of the effect of Li in model lipid membranes in amyloid toxicity in realtion to Alzheimer's Disease
Currently: -----


HARRY KUMBHANI
Fall 2020
    Undergraduate Co-op Student (Biology)
Research: Quantum neuroscience studies on connected cellular networks in relation to neuronal communication mechanisms
Currently: -----


DUALE OMAR
Fall 2020
    NSERC USRA Undergraduate Student (Life Physics)
Research: Quantum Neuroscience: Effect of Li isotopes on electrical activity in neuronal brain tissues
Currently: -----


STEPHEN TURNBULL
Ph.D. Student (Physics)
Research: The effect of melatonin on Alzheimer's disease using localized surface plasmon resonance (LSPR) and surface enhanced raman scattering (SERS)
Currently: -----


DEEPKANWAL SINGH MUNDRA
Winter 2021 
    Undergraduate Co-op Student (Physics)
Research: General anesthetics and their link to neurodegeneration
Currently: -----


AARON KENNY-WILBY

    Undergraduate Honours Student (Science)
Research: Biosensor technologies: detection of cannabis by surface plasmon resonance (SPR) with Sanntek
Currently: -----


TIMOTHY SOROCHKIN
Jan 2019 - Apr 2019
    NSERC Undergraduate Co-op Student
Research: Quantum biology: effect of Li isotopes on neuronal membrane potential
Currently: ----


DR. FRANCIS HANE
Nov 2013 - Dec 2018
    Collaborator and Volunteer Research Associate
Sep 2009 - Oct 2013
    PhD Student (Biology)
Sep 2007 - Jun 2009
    MSc Student (Biology)
Research: Effect of metal ions and amyloid aggregation inhibitors on the unbinding force, kinetics and free energy landscape of amyloid-beta dimers using single molecule dynamic force spectroscopy
Currently: PDF at Thunder Bay Regional Research Institute (Lakehead), Pilot


JENNIFER LOU
Jun 2017 - Aug 2017
    NSERC Summer Student
Jan 2015 - Aug 2015
    Undergraduate Volunteer (Life Physics)
Sep 2014 - Dec 2014
    NSERC Undergraduate Co-op
Research: AFM to test novel amyloid inhibitors
Currently: MSc Student at University of Toronto


JAMES LIVINGSTONE
Sep 2016 - May 2017
    Undergraduate Honours Student (Biomedical Sciences)
Research: Effect of amyloid and melatonin on neuronal plasticity
Currently: BSc from University of Waterloo


MAUREEN LI
May 2016 - Aug 2016
    BSc Student (Biology)
Jan 2015 - Apr 2016
    Undergraduate Honours Student
Research: AFM study of daptomycin and derivatives on monolayers
Currently: PharmD Student at University of Waterloo


JEFF LAM
May 2016 - Aug 2016
    BSc Student (Biology)
Jan 2015 - Apr 2016
    Undergraduate Honours Student
Research: Studying the effect of daptomycin and derivatives on monolayers
Currently: MSc Student atMcMaster University


JINGSI GONG
Jan 2016 - Apr 2016
    Undergraduate Honours Student (Physics)
Sep 2015 - Dec 2015
    Undergraduate Co-op Student
Research: Developing lipid-based biosensing platform for SPR
Currently: ------


JACOB BRUNNING
Jan 2016 - Apr 2016
    Undergraduate Honours Student (Materials & Nanosciences)
Sep 2015 - Dec 2015
    Undergraduate Co-op Student
Research: Raman spectroscopy for melatonin and amyloid
Currently: BSc Student at University of Waterloo


FIORELLA VILLANUEVA
Sep 2015 - Dec 2015
    Undergraduate Volunteer (Materials & Nanosciences)
Research: Raman spectroscopy for melatonin and amyloid
Currently: BSc Student at University of Waterloo


JOCELYN VAN LEEUWEN
Sep 2015 - Dec 2015
    Undergraduate Volunteer (Materials & Nanosciences)
Research: Cell viability in relation to amyloid inhibitors University of Waterloo


MICHELLE WYSOCKI
May 2015 - Dec 2015
    High School Volunteer
Research: Interaction of daptomycin with model membranes
Currently: Undergraduate Student at University of Toronto


KELSEY FORREST
Jan 2015 - Jun 2015
    Undergraduate Honours Student (Life Physics)
Research: Study of lipid monolayers to mimic bacterial membranes using KPFM
Currently: MSc Student (Physics) at Ryerson University


MELISSA PRICKAERTS
May 2014 - Dec 2014
    Undergraduate Honours Student (Biochemistry)
Research: AFM and KPFM study of lipid-Gemini surfactant monolayers
Currently: BSc Student at University of Waterloo


DR. VINCE CHOI
Sep 2009 - Oct 2014
    PhD Student (Biology)
Sep 2008 - Apr 2009
    Undergraduate Honours Student (Biology)
Research: AFM study of effect of melatonin on model lipid membranes in relation to Alzheimer's Disease
Currently: ----------


VICTORIA HIGGINS
May 2013 - Aug 2014
    NSERC Undergraduate Student (Biomedical Sciences)
Sep 2013 - Apr 2014
    Honours Student
May 2013 - Aug 2013
    NSERC Undergraduate Student
Research: Study of bacterial and host membranes using fluorescence spectroscopy
Currently: MSc Student at University of Toronto


REID HAYES
Jan 2014 - Apr 2014
    Undergraduate Co-op Student (Mathematical Physics)
Research: Study of amyloid-beta and its interactions using atomic force spectroscopy
Currently: BSc Student at University of Waterloo


CODY SHIRRIFF
Sep 2013 - Jan 2014
    Undergraduate Volunteer (Biology)
Research: Review on nutrition and Alzheimer's Disease
Currently: MSc Student at University of Waterloo


GURJIT MANN
Sep 2013 - Dec 2013
    Undergraduate Volunteer (Business & Health Sciences)
Research: Review of the pharmaceuticals involved in Alzheimer's research
Currently: BA/AHS Student at University of Waterloo


THIVAHER PARAMSOTHY
Sep 2013 - Dec 2013
    Volunteer (BSc Health Sciences)
Research: Review of current Alzheimer's detection/prevention
Currently: BSc Student at University of Waterloo


CLAIRE TINKER-MILL
October 2013
    Visiting PhD Student (Biophysics) from Lancaster University
Research: Nanostructure of amyloid fibrils
Currently: PhD Student at Lancaster University


DR. SIMON ATTWOOD
Mar 2011 - Sep 2013
    Postdoctoral Fellow (Physics)
Research: Study of lipid membranes using atomic force spectroscopy and microscopy
Currently: Postdoctoral Fellow at Imperial College London


OSMAN KAHIYE
Sep 2013 - Jan 2014
    Undergraduate Honours Student (Biomedical Sciences)
May 2013 - Aug 2013
    NSERC Undergraduate Student
Research: AFM study of both nanoparticles and mitochondrial membrane
Currently: BSc from University of Waterloo


KEELY HAMMOND
May 2013 - Aug 2013
    NSERC Undergraduate Student (Biophysics) from University of British Columbia
Research: Study of mixed lipid monolayers as neuronal membrane model (AFM/KPFM/LB)
Currently: BSc from University of BC


FLORENT MARTIN
Jun 2013 - Jul 2013
    Visiting MS Student(Physics) from University of Burgundy (France)
Research: AFM combined with microfluidic device to study amyloid-lipid interactions
Currently: Materials Engineer


PATRICIA JOHNSON
Jan 2013 - Apr 2013
    Undergraduate Student (Physics)
Research: Effect of DHA on amyloid fibril formation
Currently: MSc Student at University of Western Ontario


GUSTAVO (TAVO) CORDOVA
Sep 2010 - Sep 2012
    Masters Student (Biology - Nanotechnology)
Research: AFM/MFM study of interaction of magnetic nanoparticles with lipid membrane
Currently: Medical Student at University of Limerick


DR. RAVI GAIKWAD
Jun 2010 - Jul 2012
    Postdoctoral Fellow (Physics)
Research: AFM and KPFM study of lipid monolayers and membranes
Currently: Postdoctoral Fellow at University of Alberta


NANCY ELEWA
Sep 2011 - Aug 2012
    PhD Student (Physics)
Research: Interaction of antimicrobial peptides with lipid membrane
Currently: Lecturing assistant at Ain Shams University


TAMARA ROZINA
Sep 2011 - Apr 2012
    Masters Student (Physics)
Research: AFM and fluorescence study of lipid monolayers
Currently: MSc from University of Waterloo


OLZHAS TAZABEKOV
Sep 2011 - Apr 2012
    Masters Student (Physics - Grenoble INP)
Research: Development of novel multiprobe microchip-based AFM technology
Currently: PhD Student at University of Waterloo


VICTOR MALKOV
Sep 2011 - Apr 2012
    Undergraduate Volunteer (Mathematical Physics)
May 2011 - Aug 2011
    Undergraduate Research Assistant (Part-Time)
Jan 2011 - Apr 2011
    Undergraduate Co-op Student (Mathematical Physics)
Research: AFM breakthrough forces in lipid membranes
Currently: MSc Student at Carleton University


STEVEN CHEUNG
Sep 2011 - Apr 2012
    Undergraduate Honours Student (Biology)
May 2011 - Aug 2011
    Undergraduate Volunteer
Research: AFM study of lipid deposits on contact lenses
Currently: MSc Student at University of Waterloo


HEATHER WANG
Sep 2011 - Apr 2012
    Undergraduate Honours Student (Biology)
May 2011 - Aug 2011
    Undergraduate Volunteer
Research: Interactions of nanoparticles with plants
Currently: Dentistry Student at University of Western Ontario


JEFF BROCKHOUSE
Sep 2010 - Apr 2011
    Undergraduate Honours Student (Physics)
Sep 2009 - Aug 2010
    Undergraduate Volunteer
May 2009 - Aug 2009
    Undergraduate Co-op Student
Research: Application of QCM to study lipid membranes
Currently: Paramedic


GARY TRAN
Sep 2010 - Apr 2011
    Undergraduate Honours Student (Biology)
May 2010 - Aug 2010
    Undergraduate Volunteer
Research: Effect of DHA on amyloid fibril formation
Currently: Medical Student at University of Toronto


LAETITIA TAM
Sep 2010 - Apr 2011
    Undergraduate Honours Student (Biology)
Sep 2009 - Apr 2010
    Undergraduate Volunteer
Research: Nanofabrication of porous substrates for biosensing
Currently: Medical Student at University of Toronto


MIKE ROSSI
Sep 2010 - Apr 2011
    Undergraduate Honours Student (Physics)
Sep 2009 - Apr 2010
    Undergraduate Volunteer
Research: AFM and QCM study of lipid membranes
Currently: Co-Founder of Sweet Tooth


SARAH HAGEDORN
May 2011 - Aug 2011
    Undergraduate Volunteer (Biology)
Sep 2010 - Apr 2011
    Undergraduate Honours Student
May 2010 - Aug 2010
    Undergraduate Volunteer
Research: AFM study of lens deposits
Currently: PharmD (UofWaterloo), Optometrist


MAHMOUD YOUSSEF
May 2011 - Aug 2011
    NSERC Undergraduate Student (Biology)
Research: AFM study of model monolayers
Currently: Medical Student at Deakin University


HEATHER RUSSELL
2011 - 2011
    Masters Student (Physics) (Perimeter Institute International Student)
Research: Theoretical study to understand the breakthrough forces measured in lipid membranes
Currently: PhD Student at Washington University


ERIN FAUGHT
Sep 2009 - Apr 2010
    Undergraduate Honours Student (Biology)
Jan 2009 - Aug 2009
    Undergraduate Co-op Student
Sep 2007 - Apr 2008
    Undergraduate Volunteer
Research: Effect of cortisol on lipid membrane structure
Currently: PhD Student at University of Calgary


BRADLEY MOORES
Sep 2008 - Apr 2010
    Masters Student (Physics)
Sep 2007 - Apr 2008
    Undergraduate Honours Student (Physics)
Research: Development of novel KPFM technique for biological applications
Currently: PhD Student at MIT


HOLGER PETERS
May 2010 - Aug 2011
    Visiting Masters Student (Physics) from Karlsruher University (Germany)
Research: AFM and fluorescence study of effect of cholesterol on lipid membranes
Currently: Software Engineer


RYAN SPELLER
May 2010 - Aug 2010
    Undergraduate Research Assistant (Physics)
Sep 2009 - Apr 2010
    Undergraduate Honours Student
Research: Application of SPR to study amyloid-lipid intereactions
Currently: Trading Products Associate at BMO Capital Markets


MEHWISH IDREES
May 2010 - Aug 2010
    NSERC Undergraduate Student (Health Studies)
Research: Effect of SDS on amyloid fibril formation
Currently: Health professional


JANET SIMONS
May 2008 - Aug 2008
    NSERC Undergraduate Student (Biology)
Research: Amyloid fibrillization on modified substrates
Currently: Medical Biochemistry Resident at McMaster