Solid
phase
microextraction
(SPME)
is
a
rapid
growing
sample
preparation
technique
used
for
analytical
applications.
We
have
developed
a
mechanistic
mathematical
model
for
the
processes
occurring
in
SPME
extraction
of
analyte
from
a
sample.
The
parameters
that
contribute
to
the
uptake
kinetics
of
the
SPME
has
been
computationally
simulated
with
Comsol
MultiphysicsTM.
We
are
currently
developing
mathematical
models
which
will
provide
a
clearer
understanding
of
the
SPME
processes
and
optimum
experimental
parameters
without
the
need
to
perform
a
large
number
of
experiments
in
the
laboratory.
This
research
project
is
in
collaboration
with
Professor
Janus
Pawliszyn
of
Department
of
Chemistry,
University
of
Waterloo. The
respective
publications
of
this
project
is
available
in here.
Thesis: Numerical
Modeling
of
Solid-Phase
Microextraction:
Binding
Matrix
Effect
on
EquilibriumTime