Professor Unger, Professor Ioannidis and in collaboration with Robert Enouy have research interests in developing unstructured mesh models of human organs to replicate details of their spatial geometry and internal structure. This will permit detailed resolution of the mass transport of components between the various interstitial fluids in within the pore structure, and in contact with the exterior of these organs. A specific organ of interest is the kidney. A key attribute of the model is to simulate the reactive transport of components on the tissue surfaces. An outcome of our approach is to mechanistically assess pharmaceutical dosing as a strategy to effect an improvement in patients’ health.