WIN Thematic Seminar: Professor Evelyn Yim & Yuan Yao
Cells interact with biochemical signals and biophysical signals, such as rigidity and topography, in their extracellular matrix microenvironment. An ideal scaffold for tissue engineering application should mimic the microenvironment and present the appropriate biochemical and biophysical cues such as topographies to regulate cellular responses. Our research group is interested in studying the interfacial interactions of cells with the extracellular substrate and how to apply this knowledge to stem cell differentiation and tissue engineering applications. In this presentation, strategies on engineering cell-materials interface, such as incorporating topographies on biomaterials for different application for vascular and corneal repair will be discussed.