Publications

2021

Damian, F., M. Harati, J. Schwartzenhauer, O. van Cauwenberghe, and SD. Wettig, "Challenges of Dissolution Methods Development for Soft Gelatin Capsules", Pharmaceutics, vol. 13, issue 2, 02/2021.

Callender, S.P., and S.D. Wettig, "Phase Behavior of Non‐Ionic Surfactant‐Medium Chain Triglyceride‐Water Microemulsion Systems", Journal of Surfactants and Detergents, vol. 24, issue 4, pp. 26, 05/2021.

Ye, F., D. Chang, A. Ayub, K. Ibrahim, A. Shahin, R. Karimi, S. Wettig, J. Sanderson, and K.P. Musselman, "Synthesis of Two-Dimensional Plasmonic Molybdenum Oxide Nanomaterials by Femtosecond Laser Irradiation", Chemistry of Materials, vol. 33, issue 12, pp. 11, 06/2021.

2020

Ahmed, N., B. Kermanshahi, S.M. Ghazani, K. Tait, M. Tcheng, A. Roma, S.P. Callender, R.W. Smith, W. Tam, S.D. Wettig, et al., "Avocado-derived polyols for use as novel co-surfactants in low energy self-emulsifying microemulsions", Scientific Reports, vol. 10, issue 1, pp. 14, 03/2020.

McLachlana, A., K. Singh, M. McAlduffab, G. D. Marangoni, S. Shortall, and S. D. Wettig, "m-s-m cationic gemini and zwitterionic surfactants – a thermodynamic analysis of their mixed micelle formation", RSC Advances, vol. 10, issue 6, pp. 12, 01/2020.

Shortall, S.M., G.D. Marangoni, and S.D. Wettig, "Mixing behaviour of Pluronics with gemini surfactant/plasmid DNA condensates: effect of Pluronic composition", Physical Chemistry Chemical Physics, vol. 22, issue 45, 2020.

2019

Aborig, M., P. R. V. Malik, S. Nambiar, P. Chelle, J. Darko, A. Mutsaers, A. N. Edginton, A. Fleck, E. Osei, and S. D. Wettig, "Biodistribution and Physiologically-Based Pharmacokinetic Modeling of Gold Nanoparticles in Mice with Interspecies Extrapolation.", Pharmaceutics, vol. 11, issue 4, April 2019.

Huang, J., P. X. Chen, and S. D. Wettig, "Fluorescence-based techniques to assess the miscibility and physical stability of a drug-lipid complex.", Canadian Journal of Chemistry, vol. 97, issue 6, pp. 8, April 2019.

Huang, J., P. X. Chen, M. A. Rogers, and S. D. Wettig, "Investigating the phospholipid effect on the bioaccessibility of rosmarinic acid-phospholipid complex through a dynamic gastrointestinal in vitro model.", Pharmaceutics, vol. 11, issue 4, 2019.

Madkhali, O., G. Mekhail, and S.D. Wettig, "Modified Gelatin Nanoparticles for gene delivery” ", International Journal of Pharmaceutics, vol. 554, pp. 11, 01/2019.

2018

Slavcev, R. A., S. Wettig, and Z. Zeng, "Nanomedicine: Gene Delivery, Imaging and Evaluation Systems", Experientia Supplementum, no. 110, Cham, Springer International Publishing, pp. 125, 2018.

Sum, C. H., S. M. Shortall, S. Wong, and S. D. Wettig, "Non-viral Gene Delivery", Nanomedicine. Experientia Supplementum, vol. 110, Cham, Springer International Publishing, pp. 66, 2018.

Sum, C. H., S. M. Shortall, J. A. Nicastro, and R. Slavcev, "Specific Systems for Imaging", Nanomedicine. Experientia Supplementum, vol. 110, Cham, Springer International Publishing, pp. 29, 2018.

Shortall, S.M., and S.D. Wettig, "Cationic Gemini Surfactant-Plasmid Deoxyribonucleic Acid Condensates as a Single Amphiphilic Entity", The Journal of Physical Chemistry B, vol. 122, issue 1, pp. 5, 11/2017, 2018.

Xu, L., A.R. Tetreault, H.H. Khaligh, I.A. Goldthorpe, S.D. Wettig, and M.A. Pope, "Continuous Langmuir-Blodgett Deposition and Transfer by Controlled Edge-to-Edge Assembly of Floating 2D Materials.", Langmuir, vol. 35, issue 1, pp. 9, 12/2018.

Nambiar, S., O. Ernest, F. Andre, J. Darko, A.J. Mutsaers, and S. Wettig, "Synthesis of curcumin functionalized gold nanoparticles and cytotoxicity studies in human prostate-cancer cell line", Applied Nanoscience, vol. 8, issue 3, pp. 11, 03/2018.

2017

Moghadama, T.F., S. Azizian, and S.D. Wettig, "Effect of Spacer Length on the Interfacial Behavior of N,N΄-Bis(dimethylalkyl)-alpha,omega-Alkanediammonium Dibromide Gemini Surfactants in the Absence and Presence of ZnO Nanoparticles", Journal of Colloid and Interface Science, vol. 486, pp. 7, 01/2017.

Callender, S.P., J.A. Mathews, K. Kobernyk, and S.D. Wettig, "Microemulsion utility in pharmaceuticals: Implications for multi-drug delivery", International Journal of Pharmaceutics, vol. 526, issue 1-2, pp. 18, 06/2017.

Islam, M.S., S.M. Shortall, G.M. Mekhail, S.P. Callender, O. Madkhali, Z. Bharwani, D. Ayyash, K. Kobernyk, and S.D. Wettig, "Self-assembly, Aggregation, Micellization studies of Cationic Gemini Surfactants associated with Various Counterions", Physical Chemistry Chemical Physics, vol. 17, pp. 10, 05/2017.

A. Muslim, A., D. Ayyash, S.S. Gujrala, P.P.N. Rao, and S.D. Wettig, "Synthesis and Characterization of Asymmetrical Gemini Surfactants", Physical Chemistry Chemical Physics, vol. 19, pp. 10, 2017.

2016

Damian, F., M. Harati, V. Pathak, J. Schwartzenhauer, D. Durham, V. Quiquero, O. van Cauwenberghe, and SD. Wettig, "Development of a Discriminating Dissolution Method for Immediate-Release Soft Gelatin Capsules Containing a BCS Class II Compound", Dissolution Technologies, vol. 23, issue 4, pp. 8, 11/2016.

Ahmed, T., AO. Kamel, and SD. Wettig, "Interactions between DNA and Gemini surfactant: impact on gene therapy: part I", Nanomedicine (Lond.), vol. 11, pp. 306, 01/2016.

Ahmed, T., AO. Kamel, and SD. Wettig, "Interactions between DNA and gemini surfactant: impact on gene therapy: part II", Nanomedicine (Lond.), vol. 11, pp. 18, 2016.

A Muslim, al., D. Ayyash, SS. Gurjal, GM. Mekhail, PRP. Nekkar, and SD. Wettig, "Synthesis and Characterization of Asymmetrical Gemini Surfactants", Physical Chemistry Chemical Physics, 12/2016.

Mekhail, GM., AO. Kamel, GAS. Awad, ND. Mortada, RL. Rodrigo, PA. Spagnuolo, and SD. Wettig, "Synthesis and evaluation of alendronate modified gelatin biopolymer as a novel osteotropic nanocarrier for gene therapy", Nanomedicine (Lond.), vol. 11, pp. 2273, 08/2016.

2015

Sum, CH., N. Nafissi, RA. Slavcev, and SD. Wettig, "Physical Characterization of Gemini Surfactant-Based Synthetic Vectors for the Delivery of Linear Covalently Closed (LCC) DNA Ministrings", PLoS One, vol. 11, 2015.

Moghadama, TF., S. Azizian, and SD. Wettig, "Synergistic behaviour of ZnO nanoparticle and gemini surfactants on the dynamic and equilibrium oil/water interfacial tension", Physical Chemistry Chemical Physics, vol. 17, pp. 7129, 02/2015.

2014

Sum, CH., RA. Slavcev, and SD. Wettig, "Impact of DNA Vector Topology on Non-Viral Gene Therapeutic Safety and Efficacy", Current Gene Therapy, vol. 4, pp. 329, 2014.

Nafissi, N., CH. Sum, SD. Wettig, and RA. Slavcev, "Optimization of a One-Step Heat-Inducible in vivo Mini DNA Vector Production System", PLoS One, vol. 9, issue 2, 02/2014.

Sum, CH., J. Chong, SD. Wettig, and RA. Slavcev, "Separation and Purification of Linear Covalently Closed (LCC) DNA by Q-Anion Exchange Membrane Chromatography", Journal of Chromatography A, vol. 1339, pp. 218, 04/2014.

2013

Moghadam, S., E. Saliaj, SD. Wettig, C. Dong, M. Ivanova, JT. Huzil, and M. Foldvari, "Effect of Chemical Permeation Enhancers on Stratum Corneum Barrier Lipid Organizational Structure and Interferon Alpha Permeability", Molecular Pharmaceutics, vol. 10, pp. 2260, 04/2013.

Wang, H., T. Kaur, N. Tavakoli, J. Joseph, and SD. Wettig, "Transfection and structural properties of phytanyl substituted gemini surfactant-based vectors for gene delivery", Physical Chemistry Chemical Physics, vol. 15, pp. 20516, 2013.

2012

Donkuru, M., SD. Wettig, RE. Verrall, I. Badea, and M. Foldvari, "Designing pH-sensitive gemini nanoparticles for non-viral gene delivery into keratinocytes", Journal of Materials Chemistry, vol. 22, pp. 6244, 02/2012.

Kaur, T., N. Nafissi, K. Sheldon, SD. Wettig, and RA. Slavcev, "Immunocompatibility of Bacteriophages as Nanomedicines", Journal of Nanotechnology, vol. 5, pp. 13, 01/2012.

Akbar, J., N. Tavakoli, G. Marangoni, and SD. Wettig, "Mixed aggregate formation in gemini surfactant/1,2-dialkyl-sn-glycero-3-phosphoethanolamine systems", Journal of Colloid and Interface Science, vol. 377, pp. 243, 04/2012.

2011

Kaur, T., N. Tavakoli, R. Slavcev, and S. Wettig, "Calorimetric investigations of non-viral DNA transfection systems", Thermodynamics - Kinetics of Dynamic Systems, vol. 2, Rijeka, Croatia, InTech Open Access Publisher, 2011.

Slavcev, R. A., S. Wettig, and T. Kaur, "Nanomedicine Based Approaches to Cancer Diagonsis and Therapy, Non-Viral Gene Therapy, Prof. Xubo Yuan (Ed.)", Non-Viral Gene Therapy, Rijeka, Croatia, InTech Open Access Publisher, pp. 34, 2011.

Pillai, R., P. Huypens, M. Huang, S. Schaefer, T. Sheinin, S.D. Wettig, and J.W. Joseph, "Aryl Hydrocarbon Receptor Nuclear Translocator/Hypoxia-inducible Factor-1β Plays a Critical Role in Maintaining Glucose-stimulated Anaplerosis and Insulin Release from Pancreatic β-Cells", Journal of Biological Chemistry, 286, 1014-1024 (2011)., vol. 286, issue 2, pp. 11, 01/2011.

Foldvari, M., I. Badea, P. Kumar, S. Wettig, R. Batta, M. King, Z. He, E. Yeboah, K. Gaspar, P. Hull, et al., "Biphasic Vesicles for Topical Delivery of Interferon Alpha in Human Volunteers and Treatment of Patients with Human Papillomavirus Infections", Current Drug Delivery, vol. 8, pp. 319, 05/2011.

Keyes-Baig, C., J. Duhamel, and SD. Wettig, "Characterization of the Behavior of a Pyrene Substituted Gemini Surfactant in Water by Fluorescence", Langmuir, vol. 27, pp. 3371, 02/2011.

Kaur, T., A. Q Adallah, N. Nafissi, SD. Wettig, B. Funnell, and RA. Slavcev, "ParAB-mediated intermolecular association of plasmid P1 parS Sites", Virology, vol. 421, pp. 201, 10/2011.

Wang, H., and S.D. Wettig, "Synthesis and aggregation properties of dissymmetric phytanyl-gemini surfactants for use as improved DNA transfection vectors", Phys Chem Chem Phys., vol. 13, issue 2, pp. 6, 2011.

Huypens, P., R. Pillai, T. Sheini, S. Schaefer, M. Huang, M.L. Odegaard, S.M. Ronnebaum, S.D. Wettig, and J.W. Joseph, "The dicarboxylate carrier plays a role in mitochondrial malate transport and in the regulation of glucose-stimulated insulin release from pancreatic β-cells", Diabetologia, vol. 54, issue 1, pp. 11, 11/2011.

2010

Donkuru, M., I. Badea, S. Wettig, M. Elsabahy, and M. Foldvari, "Advancing non-viral gene delivery: Lipid- and surfactant-based nanoparticle design strategies", Nanomedicine, vol. 5, issue 7, pp. 24, 09/2010.

Yang, P., J. Singh, S. Wettig, M. Foldvari, R.E. Verrall, and I. Badea, "Enhanced gene expression in epithelial cells transfected with amino acid-substituted gemini nanoparticles", Eur J Pharm Biopharm, vol. 75, issue 3, pp. 10, 2010.

Akbar, J.R., R. Deubry, G.D. Marangoni, and S.D. Wettig, "Interactions between gemini and nonionic pharmaceutical surfactants", Canadian Journal of Chemistry, vol. 88, issue 12, pp. 9, 12/2010.

Oguocha, I.N.A., R. Taheri, S. Yannacopoulos, W.A. Uju, R. Sammynaiken, S. Wettig, and Y.-F. Hu, "Temperature effects on the chemical composition of nickel–phosphorus alloy thin films", Thin Solid Films , vol. 518, issue 8, pp. 5, 02/2010.

Wettig, S.D., R. Deubry, J. Akbar, T. Kaur, H. Wang, T. Sheinin, J.W. Joseph, and R.A. Slavcev, "Thermodynamic Investigation of the Binding of Dissymmetric Pyrenyl-Gemini Surfactants to DNA", Physical Chemistry Chemical Physics, vol. 12, pp. 6, 05/2010.

Foldvari, M., I. Badea, S. Wettig, D. Baboolal, P. Kumar, A.L. Creagh, and C.A. Haynes, "Topical Delivery of Interferon Alpha by Biphasic Vesicles: Evidence for a Novel Nanopathway across the Stratum Corneu", Molecular Pharmaceutics, vol. 7, issue 3, pp. 12, 06/2010.

2009

Kaur, T., R.A. Slavcev, and S.D. Wettig, "Addressing the Challenge: Ovarian Cancer Gene Therapy", Current Gene Therapy, vol. 9, issue 6, pp. 25, 12/2009.

2008

Wettig, S.D., R.E. Verrall, and M. Foldvari, "Gemini surfactants: a new family of building blocks for non-viral gene delivery systems", Current Gene Therapy, vol. 8, issue 1, pp. 15, 02/2008.

2007

Wang, C., S.D. Wettig, I. Badea, M. Foldvari, and R.E. Verrall, "Investigation of Complexes Formed by Interaction of Cationic Gemini Surfactants with Deoxyribonucleic Acid", Physical Chemistry Chemical Physics, vol. 9, issue 13, pp. 13, 02/2007.

Wettig, S.D., I. Badea, R.E. Verrall, and M. Foldvari, "Structural and transfection properties of amine-substituted gemini surfactant-based nanoparticles", Journal of Gene Medicine, vol. 9, issue 8, pp. 9, 07/2007.

Wang, C., S.D. Wettig, M. Foldvari, and R.E. Verrall, "Synthesis, Characterization, and Use of Asymmetric Pyrenyl-Gemini Surfactants as Emissive Components in DNA-Lipoplex Systems", Langmuir, vol. 23, issue 17, pp. 6, 07/2007.

Wettig, S.D., C. Wang, R.E. Verrall, and M. Foldvari, "Thermodynamic and aggregation properties of aza- and imino-substituted gemini surfactants designed for gene delivery", Physical Chemistry Chemical Physics, vol. 9, issue 7, pp. 6, 12/2006, 2007.

Badea, I., S.D. Wettig, R.E. Verrall, and M. Foldvari, "Topical non-invasive gene delivery using gemini nanoparticles in interferon-γ deficient mice", European Journal of Pharmaceutics and Biopharmaceutics, vol. 65, issue 3, pp. 8, 2007.

2006

MacNaughton, J.B., A. Moewes, J.S. Lee, S.D. Wettig, H.-B. Kraatz, L.Z. Ouyang, W.Y. Ching, and E.Z. Kurmaev, "Dependence of DNA Electronic Structure on Environmental and Structural Variations", Journal of Physical Chemistry B , vol. 110, issue 32, pp. 7, 08/2006.

MacNaughton, J.B., E.Z. Kurmaev, L.D. Finkelstein, J.S. Lee, S.D. Wettig, and A. Moewes, "Electronic structure and charge carriers of metallic DNA investigated with soft x-ray spectroscopy", Physical Reviews B, vol. 73, issue 20, pp. 7, 2006.

MacNaughton, J.B., M.V. Yablonskikh, A.H. Hunt, E.Z. Kurmaev, J.S. Lee, S.D. Wettig, and Moewes, "Solid versus solution: Examining the electronic structure of metallic DNA with soft x-ray spectroscopy", Physical Reviews B, 73, 125101-1 – 5 (2006)., vol. 74, issue 12, pp. 5, 09/2006.

Foldvari, M., I. Badea, S. Wettig, R. Verrall, and M. Bagonluri, "Structural Characterization of Novel Micro- And Nano-Scale Non-Viral DNA Delivery Systems for Cutaneous Gene Therapy", Journal of Experimental Nanoscience, vol. 1, issue 2, pp. 12, 06/2006.

2005

Li, X., S.D. Wettig, and R.E. Verrall, "Isothermal Titration Calorimetry and Dynamic Light Scattering Studies of Interactions between Gemini Surfactants of Different Structure and Pluronic Block Copolymers", Journal of Colloid and Interface Science, vol. 282, issue 2, pp. 12, 02/2005.

Skinner, R., J. Lee, Y-F. Hu, D-T. Jiang, P. Aich, S. Wettig, J. Maley, and R. Sammynaiken, "Local Structure of M-DNA at the Nitrogen K-edge: Evidence towards a metal ion induced conduction band", Journal of Nanoscience and Nanotechnology, vol. 5, issue 9, pp. 4, 09/2005.

Wettig, S.D., D.O. Wood, P. Aich, R.J.S. Skinner, and J.S. Lee, "M-DNA: A novel metal ion complex of DNA studied by fluorescence techniques", Journal of Inorganic Biochemistry, vol. 99, issue 11, pp. 9, 11/2005.

Li, X., S.D. Wettig, M. Foldvari, and R.E. Verrall, "Synthesis and Solution Properties of Gemini Surfactants Containing Oleyl Chains", Physical Chemistry Chemical Physics, vol. 7, issue 17, pp. 7, 07/2005.

2004

Li, X., S.D. Wettig, and R.E. Verrall, "Interactions between 12-EOx-12 Gemini Surfactants and Pluronic ABA Block Copolymers (F108 and P103) Studied by Isothermal Titration Calorimetry", Langmuir , vol. 20, issue 3, pp. 8, 12/2003, 2004.

Moewes, A., J. MacNaughton, R. Wilks, J.S. Lee, S.D. Wettig, H.-B. Kraatz, and E.Z. Kurmaev, "Soft X-Ray Spectroscopy of Nucleobases, B-DNA and Ferrocene-proline conjugates", Journal of Electron Spectroscopy and Related Phenomena, vol. 137-149, pp. 6, 03/2004.

2003

Wettig, S.D., C. Li, Y. Long, and J.S. Lee H. B. Kraatz, "M-DNA: a self-assembling molecular wire for nanoelectronics and biosensing", Analytical Sciences, vol. 19, issue 1, pp. 4, 01/2003.

Wettig, S.D., G.A. Bare, R.J.S. Skinner, and J.S. Lee, "Signal Transduction Through Dye-labeled M-DNA Y-branched Junctions: Switching Modulated by Chemical Reduction of Anthraquinone", Nanoletters, vol. 3, issue 5, pp. 6, 04/2003.

Wettig, S.D., X. Li, and R.E. Verrall, "Thermodynamic and Aggregation Properties of Gemini Surfactants with Ethoxylated Spacers in Aqueous Solution", Langmuir , vol. 19, issue 9, pp. 5, 03/2003.

Wettig, S.D., D.O. Wood, and J.S. Lee, "Thermodynamic Investigation of M-DNA; A Novel Metal Ion – DNA Complex", Journal of Inorganic Biochemistry, vol. 94, issue 1-2, pp. 6, 02/2003.

2002

Aich, P., R.J.S. Skinner, S.D. Wettig, R.P. Steer, and J.S. Lee, "Long Range Molecular Wire Behaviour in a Metal Complex of DNA", Journal of Biomolecular Structure and Dynamics, vol. 20, issue 1, pp. 6, 08/2002.

Jenkins, K. M., S.D. Wettig, and R.E. Verrall, "Studies of the Aggregation Behavior of Cyclic Gemini Surfactants", Journal of Colloid and Interface Science, vol. 247, issue 2, pp. 7, 2002.

Wettig, S.D., P. Nowak, and R.E. Verrall, "Thermodynamic and Aggregation Properties of Gemini Surfactants with Hydroxyl Substituted Spacers in Aqueous Solution", Langmuir , vol. 18, issue 14, 06/2002.

2001

Wettig, S.D., and R.E. Verrall, "Studies of the Interaction of Gemini Surfactants with Polymers and Triblock Copolymers in Aqueous Solution", Journal of Colloid and Interface Science, vol. 244, issue 2, pp. 9, 12/2001.

Wettig, S.D., and R.E. Verrall, "Thermodynamic Studies of Aqueous m-s-m Gemini Surfactants", Journal of Colloid and Interface Science, vol. 235, issue 2, pp. 7, 03/2001.