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Welcome to the Applied Virus and Complex Biologics Bioprocessing Lab
The Applied Virus and Complex Biologics Bioprocessing Lab (Aucoin Lab) is part of the BioWorks Team in the Department of Chemical Engineering at the University of Waterloo, situated on the traditional territory of the Attawandaron, Anishinaabeg, and Haudenosaunee peoples.
Our research combines biology, engineering, and process science to better understand and control biological systems. We develop technologies for the production of viruses, virus-like particles, vaccines, gene therapy vectors, and other complex biologics, with the goal of addressing important challenges in human health and biomanufacturing.
A Collaborative and Supportive Team
Students and trainees are the foundation of our lab. We strive to create an environment where people support one another, develop professionally, and pursue their own goals. Lab members regularly collaborate with academic, industrial, and international partners, and our alumni have gone on to careers in academia, biotechnology start-ups, and global pharmaceutical companies.
Diversity, Inclusion, and Opportunity
We welcome applications from talented individuals of all backgrounds and experiences. We are committed to fostering an inclusive, respectful, and collaborative research environment where everyone can thrive.
We particularly encourage applications from Indigenous (First Nations, Inuit, and Métis) and Black scholars and support opportunities such as the IBET Momentum Fellowship through the Indigenous Black Engineering and Technology PhD Project. We also recognize that career interruptions, including parental and medical leaves, are a normal part of life and should not be barriers to pursuing graduate studies or research careers.
Join Our Team
We are always interested in hearing from prospective students and trainees. Funding may be available through research grants, scholarships, fellowships, and external funding programs. If you are excited by interdisciplinary research at the interface of biology and engineering, we encourage you to contact us and apply.
The Aucoin Lab works closely with many outstanding research groups at Waterloo, including the Ward, Slavcev, Ingalls, Budman, Abukhdeir, Euler, and Liu laboratories. We are a proud member of the BioWorks Team.
Research Translation and Start-Up Engagement
The Aucoin Laboratory supports the translation of scientific and engineering ideas into biotechnology and health-related ventures. Our contributions have included technical advising, experimental design, research and development planning, graduate research supervision, bioprocess expertise, and guidance through research-ethics requirements.
Current engagements
CELLECT Laboratories Inc.
CELLECT is developing a non-invasive menstrual-sample collection technology for HPV and cervical-cancer screening. The technology originated through a student design capstone project at the University of Waterloo co-supervised by Marc Aucoin and is being advanced through graduate research supervised by Marc Aucoin.
HeadFirst Inc.
HeadFirst is developing a rapid, saliva-based test for concussion screening. The technology originated through a student design capstone project at the University of Waterloo co-supervised by Marc Aucoin. Marc Aucoin serves as a technical advisor, supporting research and development and helping the company navigate the research-ethics requirements associated with device testing.
Previously supported ventures
Membio Inc.
Membio developed scalable, single-use bioreactor technology for cell manufacturing. Its bioreactor technology was acquired by ABEC in 2024. Megan Logan and Mark Bruder were part of this venture while doing their PhD their work in the Aucoin lab.
ExVivo Labs—later Kenota Health
ExVivo Labs was co-founded by former Aucoin Laboratory PhD student Eric Blondeel to develop faster and less invasive diagnostic testing. The company subsequently became Kenota Health and continued developing point-of-care diagnostic technologies.
News
Congratulations Nicholas!
Congratulations to Nicholas Cheng for successfully defending his Master's of Science in Biology: Characterization of virus-like particles from the BEVS platform with a special focus on gradient ultracentrifugation
Most Ambitious
BetaKit has highlighted our work (Brian Ingalls, Sara Sadr and Bahram Zargar) on their most ambitious list for our work on engineering Clostridium sporogenes to improve its utility as a cancer therapeutic. https://mostambitious.betakit.com/
Dean of Science Award for Spring 2026
Congratulations to Mehraveh Hosseinali on completing her Master's degree in Pharmacy and earning the Dean of Science Award for Spring 2026, which recognizes the exceptional creativity and excellence demonstrated in her thesis research. We are very proud of her!