We have shown that the fine structure of the gradient of refractive index in the crystalline lens can be influenced by visual experience. Work is continuing to elucidate the feedback between optical image quality on the retina, and structural changes in the eye. This work was recognized by the Rank Prize in Optoelectronics.
If a lens is placed on an animal eye, the rate of eye growth will change to maintain a focused image on the retina. We have shown for the first time that the optical structure of the eye also changes in a way that worsens the quality of the image on the retina. Optical modeling and experiments are continuing.